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# Sr. Principal Scientist - MES Data and Integration Lead

- **Company:** The Lilly Company
- **Location:** Lebanon, IN, United States
- **Experience:** Expert
- **Salary:** $66,000.0 - $171,600.0
- **Contract:** Permanent contract
- **Skills:** Data Analysis, System Configuration, Data Governance, Data Integration, Digital Technology, SAP (Applications), Data Processing
- **Published:** June 2, 2026
- **Apply:** https://dejobs.org/x/x/125E418F6C9A4683B94830F57044CD35/job/

## About the Role

* Bachelor's degree in Science, Engineering, or related field.
 * Minimum 5 years experience including 2 years within a GMP manufacturing environment or equivalent regulated manufacturing environment.
 * Demonstrated history of working across multi-disciplinary teams in the Automation/MES space.
 * Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.

Preferences:

 * Prior experience implementing electronic batch records preferred but not required
 * Proficiency in data analysis, ability to prioritize, attention to detail, critical decision-making skills, complex problem-solving abilities.
 * Proven ability to work independently and collaboratively within cross-functional teams. Ability to respond quickly and proactively to changing priorities within a limited timeline.
 * Oral and written communication skills that demonstrate an ability to effectively (clearly, succinctly) communicate with all levels of the organization.

Additional Information

 * Language Requirements: Fluent in English
 * This is a fully on-site position located in Lebanon, IN. Standard 8-hour shift, 5 days/week; occasional night and weekend work may be required.
 * Travel to other Lilly domestic and international locations generally not exceeding 10%

If you are passionate about process development and automation and are looking for a challenging and rewarding role, we would love to hear from you!

## Description

The Sr Principal Scientist, MES Data and Integration Lead is a critical role supporting design, deployment, and sustained operation of the Manufacturing Execution System (MES)/Electronic Batch Record (EBR) within Lilly's Lebanon API Manufacturing site. MES is foundational to enabling compliant, efficient, and digital-first GMP operations and the successful candidate will play a key role in translating manufacturing requirements into executable MES solutions, supporting system ownership responsibilities, and ensuring MES-enabled processes are robust, scalable, and inspection-ready.

This position requires comprehensive knowledge of the pharmaceutical industry, regulatory requirements, and the essential role scientists and engineers play in making medicine and creating real-world solutions. The successful candidate will represent TS/MS (Technical Services) as a business SME and act as a liaison between process scientists and automation designers. This role will focus on ensuring MES readiness through strong data governance and technical alignment of enterprise system integrations.

You'll work at the boundary of process data and manufacturing execution - with opportunities to leverage MES-generated data for continuous improvement and performance analytics.

Key Objectives/Deliverables

 * Serve as MES/EBR SME for assigned API manufacturing areas, supporting process design, system configuration, and operational readiness
 * Working with process SMEs to review and approve Product Lifecycle Management (PLM) parameters required for MES configuration
 * Ensuring complete and accurate migration of product and process data into production MES environments
 * Supporting MES system ownership activities and providing backup coverage
 * Partnering with DeltaV, SAP, and Digital Technology teams to support integration readiness, reporting, and operational dashboards following go-live
 * Partner with Operations, QA, Engineering, Automation, and Validation to ensure integrated execution and issue resolution
 * Drive standardization, harmonization, and best practices across manufacturing areas where appropriate
 * Leading MES training for operational readiness, including review and approval of training materials and coordination of rollout


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