> Markdown version of [/jobs/ext/1206119-director-clinical-data-management](https://www.wearedevelopers.com/jobs/ext/1206119-director-clinical-data-management). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Director, Clinical Data Management - **Company:** Trex Bio, Inc. - **Location:** South San Francisco, CA, United States - **Experience:** Expert - **Salary:** $260,000.0 - $275,000.0 - **Contract:** Permanent contract - **Skills:** Data Analysis, Basic Linear Algebra Subprograms, Clinical Data Management, Databases, Data Integrity, Data Strategy, Data Management, Veeva - **Published:** July 8, 2026 - **Apply:** https://trex.bio/career/senior-director-clinical-data-management/ ## About the Role * Experience: 10-15+ years of clinical data management experience. * Education: Bachelor's or Master's degree in scientific or technical field. * Skills: In-depth knowledge of EDC systems (e.g., Medidata RAVE, Veeva, etc.), CDISC standards, and hands-on experience with Regulatory submissions (IND/NDA/MAA). * Adaptability: Ability to thrive in a rapidly growing environment with changing priorities. * Communication: Excellent verbal and written skills, able to influence at the executive level. * Problem-Solving: Proactive, analytical mindset with the ability to resolve complex data issues. * Hands-on vs. Oversight: While a "Senior Director," this person will often still be involved in writing DMPs (Data Management Plans) and reviewing data listing in the EDC. * Building Infrastructure: Expected to create SOPs from scratch or heavily modify existing ones, rather than just adhering to established processes. * CRO Management: High emphasis on holding external vendors accountable to strict timelines. Small Biotech Focus: This role is highly "hands-on," requiring the leader to be a "doer" while simultaneously establishing long-term data strategy and infrastructure. * Demonstrated ability to establish strong scientific partnership with internal and external key stakeholders * Demonstrated leadership and strong communication skills with a documented track record of delivering high quality projects/submissions/trials in a global/matrix environment in pharmaceutical or biotech industry or academia or clinical CRO required * Vendor Management: Extensive experience in CRO/vendor selection and oversight. * Regulatory Submissions: Strong track record in supporting NDAs/BLAs or Phase III studies. ## Description Reporting to the VP, Clinical Operations, the Senior Director, Clinical Data Management will be accountable for the design, implementation, and execution of a data management program(s) to support decision milestones and regulatory requirements. The qualified candidate needs a strong understanding of the compliance and technical framework for data management activities and has an innovative drive to help the organization succeed and bring new cures to life., * Strategic & Operational Leadership: Develop data management plans (DMPs), establish standards (CDISC/SDTM), and oversee EDC system builds, UAT, and database locks. * CRO/Vendor Oversight: Manage external vendors, ensuring quality deliverables, strict adherence to timelines, and budget compliance. * Data Integrity & Quality: Ensure compliance with ICH/GCP, regulatory guidelines, and internal SOPs; drive query resolution and SAE reconciliation. * Cross-functional Collaboration: Partner with Clinical Operations, Biostatistics, and Medical Directors, to support study design and data analysis. * Function Building: Create and refine Data Management SOPs, processes, and technology infrastructure within a start-up, high-growth setting. ## Related Videos - [Data Science in Retail](https://www.wearedevelopers.com/videos/586-data-science-in-retail) - [Blueprints for Success: Steering a Global Data & AI Architecture](https://www.wearedevelopers.com/videos/1577-blueprints-for-success-steering-a-global-data-ai-architecture) - [Kubernetes and Microservices with Multi-Model Databases](https://www.wearedevelopers.com/videos/382-kubernetes-and-microservices-with-multi-model-databases) - [Data Science on Software Data](https://www.wearedevelopers.com/videos/162-data-science-on-software-data) - [Geometric deep learning for drug discovery](https://www.wearedevelopers.com/videos/264-geometric-deep-learning-for-drug-discovery) - [Fault Tolerance and Consistency at Scale: Harnessing the Power of Distributed SQL Databases](https://www.wearedevelopers.com/videos/1146-fault-tolerance-and-consistency-at-scale-harnessing-the-power-of-distributed-sql-databases) ## Related Articles - [Résumé-Driven Development: How IT trends affect the job market for software developers](https://www.wearedevelopers.com/magazine/59-resume-driven-development-how-it-trends-affect-the-job-market-for-software-developers) - [What’s the Difference between a Junior, Mid, and Senior Developer?](https://www.wearedevelopers.com/magazine/238-what-s-the-difference-between-a-junior-mid-and-senior-developer) - [The Biggest German Tech Companies](https://www.wearedevelopers.com/magazine/424-the-biggest-german-tech-companies) - [Highest Paying Tech Companies for Developers](https://www.wearedevelopers.com/magazine/220-highest-paying-tech-companies-for-developers) - [Coffee with Developers - Maria Apazoglou - Making AI understandable for all in production](https://www.wearedevelopers.com/magazine/475-coffee-with-developers-maria-apazoglou-making-ai-understandable-for-all-in-production) - [Data Analyst Salary in the UK](https://www.wearedevelopers.com/magazine/278-data-analyst-salary-in-the-uk)