> Markdown version of [/jobs/ext/1273902-principal-statistical-programmer](https://www.wearedevelopers.com/jobs/ext/1273902-principal-statistical-programmer). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Principal Statistical Programmer - **Company:** Vertex Pharmaceuticals Incorporated - **Location:** Boston, MA, United States (Remote available) - **Experience:** Expert - **Salary:** $149,200.0 - $223,800.0 - **Contract:** Permanent contract - **Skills:** Data Analysis, Software Applications, SAS (Software), SAS/STAT, System Testing, Data Management - **Published:** July 15, 2026 - **Apply:** https://diversityjobs.com/main/sendform/8/8/28176/1/17573543?backUrl=%2Fcareer%2F17573543%2FPrincipal-Statistical-Programmer-Massachusetts-Boston ## About the Role * Proficiency in all SAS language, procedures, and functions commonly used in clinical trial reporting including the Macro language, BASE SAS, SAS/STAT and SAS/GRAPH * Intermediate knowledge of CDISC Standards * Intermediate knowledge of clinical trials * Regulatory submission experiences * Effective communication (written and verbal) skills to explain difficult information Education and Experience: * Bachelors degree in a Scientific Discipline * Typically requires 5+ for M.S. or above and 8+ years for B.S. years of work experience in Biotech, Pharmaceuticals or Clinical Research Organization ## Description The Principal Statistical Programmer works with management to delegate tasks appropriately, track progress, and provide expert technical support to team members. In addition, the Principal Statistical Programmer is a designated member of clinical sub-team(s) in the role of project lead Statistical Programmer., * Works regularly with advanced features of SAS (including interfacing ability with other software applications and operating system tools) * Performs quality control checks of SAS code and output produced by other Statistical Programmers to ensure accuracy and consistency within group * Demonstrates in-depth knowledge of clinical development and medical data * Solves complex clinical trial reporting problems and demonstrates technical proficiency and exercises judgment in supporting daily operations and ensuring that study tasks are completed accurately and in a timely manner * Engages with a variety of other functions, including Statistical Programmers, Biostatisticians, Data Management, and other departments engaged in providing data and submission-related activities, often at Senior Management levels * Creates all files, documents, and analyses necessary to support an electronic submission in eCTD format, including ISS/ISE * Provides leadership to ensure compliance with Vertex SOP'S and FDA/ICH/GCP regulations * Provides technical and project management skills to create, review, and approve documentation required to support data analysis, reporting, and CDlSC data submission * Participates in project management cross-functional teams that work on standard operating procedures, guidelines, process improvements, system validation and acquisition, customization, and integration of new tools and technologies, In this Remote-Eligible role, you can choose to be designated as: 1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select 2. Hybrid: work remotely up to two days per week; or select 3. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. ## Related Videos - [Data Science on Software Data](https://www.wearedevelopers.com/videos/162-data-science-on-software-data) - [Geometric deep learning for drug discovery](https://www.wearedevelopers.com/videos/264-geometric-deep-learning-for-drug-discovery) - [Data Science in Retail](https://www.wearedevelopers.com/videos/586-data-science-in-retail) - [Times of (climate) crisis - How and why sustainable software is a must!](https://www.wearedevelopers.com/videos/988-times-of-climate-crisis-how-and-why-sustainable-software-is-a-must) - [From Bedside Beeps to Interoperable Bytes – Getting your medical devices ready to talk the IEEE 11073 language](https://www.wearedevelopers.com/videos/771-from-bedside-beeps-to-interoperable-bytes-getting-your-medical-devices-ready-to-talk-the-ieee-11073-language) - [Kettle and Pot or Peas in a Pod? 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