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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Principal Data Science Engineer - AI/ML & Algorithms - **Company:** Transmedics Inc - **Location:** Andover, MA, United States - **Experience:** Experienced - **Salary:** $151,500.0 - $215,700.0 - **Contract:** Permanent contract - **Skills:** Artificial Intelligence, Algorithm Design, Data Analysis, Software Applications, C++ (Programming Language), Information Engineering, Extract Transform Load (ETL), Data Transformation, Data Structures, Data Systems, Python (Programming Language), Machine Learning, NoSQL, NumPy, Software Architecture, Tensorflow, Standard Sql, Software Engineering, Data Processing, Pytorch, Pandas, Scikit Learn, Information Technology, Data Analytics, Machine Learning Operations - **Published:** May 14, 2026 - **Apply:** https://www.indeed.com/viewjob?jk=7fb6ba524cc3978e ## About the Role Do you have experience in Model deployment?, Do you have a Bachelor's degree?, * General Office Environment * Ability to lift up to 25 lbs. * May travel up to 10% domestically / 10% internationally, * BS/MS in Computer Science, Data Science, Engineering, Mathematics, or an equivalent combination of education and experience. * 3+ years of relevant professional experience building and deploying machine learning solutions, with specific experience in an ML engineering or data science role. * 8+ years of overall software development experience, * Proven experience designing, developing, and deploying AI/ML models in a professional setting, with specific experience in the healthcare or life sciences industry preferred. * Experience in applying AI/Machine Learning to practical uses. * Expertise in Python, including standard ML and data science libraries like scikit-learn, NumPy, and pandas. * Knowledge and hands-on experience with machine learning frameworks such as PyTorch. * Strong foundation in linear algebra, calculus, probability, and statistical modeling. * Proficiency in data manipulation, cleaning, and preprocessing techniques, as well as knowledge of SQL and NoSQL databases. * Experience with AWS data engineering services for ETL, data processing, and end-to-end development, deployment, and management of ML models. * Solid understanding of software development principles, including data structures, algorithms, and software architecture. * Excellent analytical and critical thinking skills to tackle complex, multi-layered data challenges. * Ability to clearly explain technical concepts to both technical and non-technical stakeholders. * Ability to work with the engineering and leadership teams on the functional design, process design, prototyping, testing, and training of AI/ML solutions. * Understanding of data privacy regulations like HIPAA, GDPR is a plus. * Knowledge of medical device software development with compliance to IEC-62304 and FDA guidelines is a plus. * Experience in C/C++ programming language is a plus * Must be team-oriented with outstanding interpersonal and communication skills (written and verbal). * Must be detail-oriented and highly organized. ## Description Please note that this position is not available for visa sponsorship, and we are unable to take over existing employment visa sponsorships, We are currently seeking a talented and driven Principal Data Science Engineer - AI/ML & Algorithms, to join our team. The Principal Data Science Engineer will have the opportunity to develop intelligent, data-driven solutions to improve patient outcomes and clinical workflows by contributing to the life cycle of embedded and digital clinical software applications that monitor, control and preserve donated hearts, lungs, livers, and other organs on the OCS., This position is responsible for, but not limited to, the following: * End-to-end lifecycle of data-driven software products from data exploration and model development to deployment and regulatory compliance * Data-driven model and algorithm development * Design, train, and validate machine learning and traditional algorithms for clinical decision support and automation * Ensure all data handling adheres to strict regulatory standards, including HIPAA and GDPR * Work collaboratively with clinical leads, software engineers, and product teams to translate clinical needs into technical specifications and data solutions * Implement data anonymization, pseudonymization, and secure access controls to protect sensitive patient information * Guide clinical algorithmic strategy, perform reviews, and set best practices for development and validation * Explain clinical algorithmic strategy and complex technical concepts to non-technical stakeholders * Perform other TransMedics tasks and duties as assigned/required. MANAGEMENT RESPONSIBILITIES This position manages the following positions on a daily basis. * This position will not have management responsibilities. ## Related Videos - [Vectorize all the things! 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