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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Manager, IT Infrastructure & Operations - **Company:** Amylyx Pharmaceuticals - **Location:** Cambridge, MA, United States (Remote available) - **Experience:** Experienced - **Salary:** $129,000.0 - $145,000.0 - **Contract:** Permanent contract - **Skills:** Microsoft Windows, Apple IOS, Apple Mac Systems, Microsoft Azure, Cloud Computing, Cloud Engineering, Identity and Access Management, Microsoft Office, Microsoft SharePoint, Information Technology - **Published:** July 27, 2026 - **Apply:** https://www.indeed.com/viewjob?jk=c291fc0493820e13 ## About the Role * Bachelor's degree with 5+ years of experience, or 8+ years of experience in customer-facing technical support or a similar role. * 3+ years of experience in a pharmaceutical, biotech, or clinical research environment supporting clinical trials. * Demonstrated knowledge of Azure/Entra ID and Office 365. * Experience managing cloud infrastructure for a distributed workforce. * Knowledge of office and laboratory applications, hardware, and equipment. * Strong technical background supporting Windows, macOS, iOS, iPadOS, and cloud applications. * Experience supporting telephony and mobile technologies, including Android and iOS. * Exceptional organizational skills with the ability to manage multiple priorities and maintain strong attention to detail. * Collaborative team player with strong communication and problem-solving skills. * Highly motivated and adaptable, with strong interpersonal and leadership skills. * Willing and able to provide global on-call support for employees. * Ability to work onsite in Cambridge, MA ## Description Amylyx is seeking an experienced IT professional to support our growing organization. This role requires strong technical expertise, a customer-focused mindset, and the ability to serve as the primary point of contact for IT escalations and resolutions. As a key representative of the IT team, this individual will provide responsive, high-quality support to employees across the organization., * Provide responsive IT support to all users and resolve escalated issues. * Deliver first- and second-level support through in-person, phone, and remote channels; document issues, resolutions, and service requests in the Service Management system. * Serve as the escalation point for external support partners on technical issues. * Coordinate scheduled and ad hoc software, system, and infrastructure deployments during business and non-standard hours. * Manage and optimize core ITIL service operations, including incident, event, request, problem, and access management. * Partner with Amylyx departments to deliver a consistent, high-quality user experience. * Support desktop imaging, applications, system administration, configuration, and supplier management, including hosted solutions. * Train employees and contractors on IT policies, procedures, and support practices. * Develop and maintain clear documentation for IT operational processes. * Configure, validate, and implement IT systems and services. * Administer SharePoint Online sites, permissions, libraries, governance standards, and user support to enable secure and effective collaboration. * Serve as the primary onsite, in-office IT support resource for local technology needs, including conference room systems and equipment. ## Related Videos - [Xcode development redefAIned](https://www.wearedevelopers.com/videos/100195-xcode-development-redefained) - [Developer Tools for Microsoft Azure](https://www.wearedevelopers.com/videos/450-developer-tools-for-microsoft-azure) - [Green Cloud Computing](https://www.wearedevelopers.com/videos/592-green-cloud-computing) - [Coffee with Developers - Maria Apazoglou](https://www.wearedevelopers.com/videos/1209-coffee-with-developers-maria-apazoglou) - [Develop enterprise-ready applications for Microsoft Teams with Azure resources on modern web technologies](https://www.wearedevelopers.com/videos/187-develop-enterprise-ready-applications-for-microsoft-teams-with-azure-resources-on-modern-web-technologies) - [Harnessing Apple Intelligence: Live Coding with Swift for iOS](https://www.wearedevelopers.com/videos/1515-harnessing-apple-intelligence-live-coding-with-swift-for-ios) ## Related Articles - [The Most Popular IT Jobs on the Market](https://www.wearedevelopers.com/magazine/376-the-most-popular-it-jobs-on-the-market) - [Fully Remote Software Engineer Jobs](https://www.wearedevelopers.com/magazine/447-fully-remote-software-engineer-jobs) - [How We Built a Worry-Free System That Runs for 10+ Years – And What We’d Do Again](https://www.wearedevelopers.com/magazine/751-how-we-built-a-worry-free-system-that-runs-for-10-years-and-what-we-d-do-again) - [What Are The Top Skills Required For Azure Developers?](https://www.wearedevelopers.com/magazine/77-what-are-the-top-skills-required-for-azure-developers) - [Coffee with Developers - Maria Apazoglou - Making AI understandable for all in production](https://www.wearedevelopers.com/magazine/475-coffee-with-developers-maria-apazoglou-making-ai-understandable-for-all-in-production) - [Everything a Developer Needs to Know About MCP with Neo4j](https://www.wearedevelopers.com/magazine/604-everything-a-developer-needs-to-know-about-mcp-with-neo4j)