> Markdown version of [/jobs/ext/1792575-principal-statistical-programmer-pkpd](https://www.wearedevelopers.com/jobs/ext/1792575-principal-statistical-programmer-pkpd). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md).

---

# Principal Statistical Programmer, PKPD

- **Company:** IQVIA
- **Location:** Durham, NC, United States
- **Experience:** Expert
- **Salary:** $98,200.0 - $273,200.0
- **Contract:** Permanent contract
- **Skills:** CrossOver (Software), SAS (Software)
- **Published:** July 7, 2026
- **Apply:** https://iqvia.wd1.myworkdayjobs.com/IQVIA/job/Durham-North-Carolina-United-States-of-America/Principal-Statistical-Programmer--PKPD_R1554788

## About the Role

Technical Skills

 * Expert-level SAS programming skills.
 * Strong, hands-on experience with CDISC SDTM, ADaM and TLFs.
 * Proven experience developing safety, PK, and PK/PD ADaM datasets.
 * Experience supporting POPPK/popPD/Exposure Response(ER) dataset creation workflows.
 * Solid understanding of early-phase clinical trial designs, including:
 + Phase I / First-in-Human
 + Crossover studies
 + Exposure-response analysis
 + PK parameter pooling

Experience

 * 8+ years of statistical programming experience in the pharmaceutical or CRO environment.
 * Demonstrated experience as a Lead Programmer or technical lead.
 * Prior experience working in an FSP engagement model preferred.
 * Experience supporting regulatory submissions is required.

Soft Skills

 * Strong communication and stakeholder management skills.
 * Ability to work independently while managing multiple priorities.
 * Detail-oriented with a strong commitment to quality and timelines.

Preferred Qualifications

 * Experience supporting Translational Medicine or Clinical Pharmacology groups.
 * Familiarity with internal exploratory analysis and early-phase decision-making needs.
 * Exposure to integrated summaries or pooled PK analyses across studies.



## Related Videos

- [Times of (climate) crisis - How and why sustainable software is a must!](https://www.wearedevelopers.com/videos/988-times-of-climate-crisis-how-and-why-sustainable-software-is-a-must)
- [Geometric deep learning for drug discovery](https://www.wearedevelopers.com/videos/264-geometric-deep-learning-for-drug-discovery)
- [Kettle and Pot or Peas in a Pod? A Debate on Open-Source and Proprietary Software](https://www.wearedevelopers.com/videos/1585-kettle-and-pot-or-peas-in-a-pod-a-debate-on-open-source-and-proprietary-software)
- [Reporting Active Exploits in 24 Hours: Are You Ready for the CRA?](https://www.wearedevelopers.com/videos/100248-reporting-active-exploits-in-24-hours-are-you-ready-for-the-cra)
- [Quantum DevOps - Enabling Industrial Engineering](https://www.wearedevelopers.com/videos/100282-quantum-devops-enabling-industrial-engineering)
- [How I saved 200K/yr in direct costs writing 0 code lines in K8s](https://www.wearedevelopers.com/videos/1055-how-i-saved-200k-yr-in-direct-costs-writing-0-code-lines-in-k8s)

## Related Articles

- [Résumé-Driven Development: How IT trends affect the job market for software developers](https://www.wearedevelopers.com/magazine/59-resume-driven-development-how-it-trends-affect-the-job-market-for-software-developers)
- [Data Analyst Salary in the UK](https://www.wearedevelopers.com/magazine/278-data-analyst-salary-in-the-uk)
- [Highest Paying Tech Companies for Developers](https://www.wearedevelopers.com/magazine/220-highest-paying-tech-companies-for-developers)
- [Coffee with Developers - Maria Apazoglou - Making AI understandable for all in production](https://www.wearedevelopers.com/magazine/475-coffee-with-developers-maria-apazoglou-making-ai-understandable-for-all-in-production)
- [Quick guide: How to write a Software Developer CV](https://www.wearedevelopers.com/magazine/37-quick-guide-how-to-write-a-software-developer-cv)
- [Should senior developers refuse interview coding challenges?](https://www.wearedevelopers.com/magazine/29-should-senior-developers-refuse-interview-coding-challenges)