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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Senior Information Security Engineer - **Company:** Mayo Clinic - **Location:** Rochester, MN, United States - **Experience:** Expert - **Salary:** $134,347.0 - $194,750.0 - **Contract:** Permanent contract - **Skills:** Artificial Intelligence, Data Analysis, Cyber Security, Information Systems, System Configuration, Systems Development Life Cycle, Software Engineering, Information Technology - **Published:** July 2, 2026 - **Apply:** https://www.jobmonkeyjobs.com/career/27815703/Senior-Information-Security-Engineer-Minnesota-Rochester-7459 ## About the Role Master's degree with one (1) year experience or Bachelor's degree in Computer Science, Information Systems, Engineering or related major and a minimum two (2) years' experience in the information security field required.The Information Security Senior Engineer also requires the following skills/abilities. * Understands the use and efficacy of information security tools, server configurations and controls with the ability to install, configure, test and operate them. * Able to test, implement, deploy, maintain, review and administer the infrastructure hardware and software required to effectively secure the enterprise, protect data, identify and mitigate risks * Ability to collect, process, preserve, analyze and present computer related evidence in support of network vulnerability mitigation and/or criminal, fraud, counterintelligence or law enforcement investigations. * Provides advanced technical opinions/conclusions re. security tools, trends, and controls which are supported by documented evidence, based on multiple perspectives and leverage of a variety of resources * Demonstrates a deep and broad knowledge of standard operating procedures, workflows and supporting technology across numerous critical user areas and an in-depth knowledge of multiple computing technologies either being actively used or of significant interest to Mayo; understands how systems fit into larger picture of technology at Mayo. * Capacity to work independently and willingness to seek advice/assistance. Must have one of the following certifications (or equivalent) at time of hire. In lieu of certification at time of hire, candidate must pass the exam within two years and complete the certification process once years of service requirements of the certifying body have been met. * CISSP * GSEC * CISM * OSCP * HCISPP Exemption Status Exempt Compensation Detail $134,347.20 - $194,750.40 / year Benefits Eligible Yes Schedule Full Time Hours/Pay Period 80 Schedule Details Monday to Friday 10:00AM to 7:00PM On-call Float Weekend Schedule As needed for nights and weekends International Assignment No Site Description Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. ## Description Mayo Clinic's tech culture is rooted in passion for technology, embraces innovative thinking and strives for high performance. Our teams drive change in health care through comprehensive connected health and digital transformation strategies. Some examples of our major initiatives are: * Utilizing artificial intelligence and machine learning principles to develop next generation patient centric care systems * Transforming the practice by applying data science techniques to discover new approaches to health care delivery * Leveraging Enterprise Architecture to construct integration centricity, promote data liquidity, and provide innovation support This transformation creates, connects and applies integrated knowledge to deliver the best health care, health guidance and health information to patients, customers, partners, providers, employees anywhere and anytime so the needs of the patient come first., The Senior SOC Engineer is an integral part of the organization's cybersecurity operations ensuring that security incidents are detected and responded to promptly and effectively. Responsible for identifying and analyzing security threats and incidents. Utilizes various tools and techniques to detect malicious activities and respond to them swiftly to mitigate potential damage. Consists of gathering, analyzing, and interpreting threat intelligence data to anticipate and prevent security breaches. Keeps abreast of the latest cyber threat landscape and integrates intelligence into SOC operations. Accurate documentation and reporting of security incidents are essential for developing strategies to prevent future occurrences. Prepares detailed reports on incidents and the responses taken. Works closely with other departments, such as IT, compliance, and risk management, to ensure integrated security measures are in place. Provides training and mentorship to junior analysts, enhancing their skills and knowledge in cybersecurity. Stays current with emerging threats, attack techniques, and AI/ML advancements in cybersecurity. The Information Security Senior Engineer is results oriented, multi-disciplined, and comfortable in implementing system security solutions in multi-vendor environments and acts as an information security liaison to various business units and the information technology department to assist with the security design, consultation, and technology implementation for various Mayo Clinic projects and initiatives. The incumbent also assists system users relative to information systems security matters and undertakes complex projects requiring additional specialized technical knowledge. Specifically, the Information Security Senior Engineer is knowledgeable, proficient, and experienced in: * Working with business partners within the department to achieve organizational and OIS goals * Developing required competencies by mastering fundamental tasks * Independently analyzing technology security posture and appropriate use of security defenses * Matching technical solutions with business requirements and then designing and implementing them; * Self-directed software development, testing, support/problem solving, and overall technology administration; * Organizational procedures such as the system development life-cycle; * Use of defensive measures and information to identify, analyze and report security events; * Researching and understanding pertinent information technology laws, policies and procedures * Establishing timelines and delivery of requirements * Applying IT-related laws and policies, and providing IT-related guidance throughout the software acquisition lifecycle * Collecting and analyzing information to identify vulnerabilities and potential for exploitation * Managing and administering processes and tools that enable the organization to identify, document, and access intellectual capital and information content * Executing duties governing hardware, software, and information system acquisition programs and other program management policies with minimal support ## Related Videos - [What makes Cybersecurity different for critical infrastructure?](https://www.wearedevelopers.com/videos/571-what-makes-cybersecurity-different-for-critical-infrastructure) - [Thinking Differently - How to Make Money from Cyber Attacks & Cheats](https://www.wearedevelopers.com/videos/745-thinking-differently-how-to-make-money-from-cyber-attacks-cheats) - [Data Science in Retail](https://www.wearedevelopers.com/videos/586-data-science-in-retail) - [Microservices? 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