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# Principal Statistical Programmer

- **Company:** IQVIA
- **Location:** Durham, NC, United States
- **Experience:** Expert
- **Salary:** $98,200.0 - $273,200.0
- **Contract:** Permanent contract
- **Skills:** SAS (Software), Macros, Information Technology, Data Management
- **Published:** July 11, 2026
- **Apply:** https://dejobs.org/x/x/FFDA169243A4477C84E01450FE4DE1F0/job/

## About the Role

* Bachelor's or Master's degree in Statistics, Mathematics, Computer Science, Life Sciences, or related field
 * Extensive experience as a statistical programmer , with demonstrated Principal-level responsibilities
 * Strong hands-on experience with:
 * SDTM and ADaM dataset development
 * TLF programming
 * Regulatory submission deliverables
 * Expert proficiency in base SAS and Advanced SAS with good hands on SAS Macros
 * In-depth knowledge of CDISC standards , regulatory guidelines, and submission requirements
 * Proven ability to manage complex studies independently from start to finish

## Description

We are seeking a Principal Statistical Programmer to provide full end-to-end statistical programming support across clinical development programs. This role requires deep technical expertise, leadership, and hands-on delivery, covering SDTM, ADaM, TLF development, and regulatory submission support . The Principal Statistical Programmer will serve as a subject matter expert, ensure high-quality deliverables, and contribute to programming standards and best practices., * Provide end-to-end statistical programming support for clinical studies from study setup through submission

 * Lead and perform development and validation of:
 * SDTM datasets
 * ADaM datasets
 * Tables, Listings, and Figures (TLFs)
 * Ensure all deliverables are compliant with CDISC standards and regulatory requirements
 * Support regulatory submissions (e.g., FDA, EMA), including define.xml, submission-ready datasets, and reviewer's guides
 * Serve as a Principal-level programmer , providing technical leadership and guidance to other programmers as needed
 * Contribute to and help maintain programming standards, macros, and validation processes
 * Review and approve programming deliverables to ensure accuracy, consistency, and quality
 * Collaborate closely with Biostatistics, Data Management, Clinical Operations, and Regulatory teams
 * Proactively identify risks and propose efficient, compliant solutions within timelines


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