> Markdown version of [/jobs/ext/1891205-principal-engineer-vaida-user-experience](https://www.wearedevelopers.com/jobs/ext/1891205-principal-engineer-vaida-user-experience). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Principal Engineer, VaiDA User Experience - **Company:** Vertex Pharmaceuticals Incorporated - **Location:** Boston, MA, United States (Remote available) - **Salary:** $166,640.0 - $250,000.0 - **Contract:** Permanent contract - **Skills:** HTML, JavaScript (Programming Language), Artificial Intelligence, Component-Based Software Engineering, Cascading Style Sheets (CSS), Design of User Interfaces, Human-Computer Interaction, Interaction Design, Modular Design, Performance Tuning, TypeScript, User-Centered Design, Web Engineering, Enterprise Software Applications, ReactJS, Multi-Agent Systems, Backend, Build Management, AngularJS, Information Technology, Figma, Front End Software Development - **Published:** August 2, 2026 - **Apply:** https://diversityjobs.com/main/sendform/8/8/28176/1/17791790?backUrl=%2Fcareer%2F17791790%2FPrincipal-Engineer-Vaida-User-Experience-Massachusetts-Boston ## About the Role * Bachelor's degree in Computer Science, Human-Computer Interaction, Design, Engineering, or a related field; or equivalent practical experience * Proven experience in frontend engineering, product design engineering, or UX engineering roles * Strong track record of designing and building polished, user-centered interfaces for complex applications * Experience translating technical or data-rich workflows into clear and intuitive user experiences * Demonstrated ability to own interaction design and prototyping from concept through implementation * Strong understanding of usability, accessibility, and responsive design principles * Experience collaborating cross-functionally with product managers, engineers, and stakeholders * Ability to balance user needs, technical constraints, and business goals in a fast-paced environment * Excellent communication, problem-solving, and presentation skills Technical Skills Required * Modern frontend development frameworks such as React, Angular, TypeScript, JavaScript, HTML, and CSS * Interaction design and frontend prototyping * Enterprise UI development and scalable design systems * Experience with design tools such as Figma or similar prototyping platforms * Workflow visualization and complex interface design * Usability and human-centered design practices * Frontend performance optimization * Component-based architecture and reusable UI patterns * Collaboration with backend and AI/agent-based systems * Accessibility standards and inclusive design implementation Preferred Skills * Experience designing for AI-powered products, conversational interfaces, or multi-agent systems * Experience leveraging AI-assisted tools to accelerate frontend prototyping, design exploration, or development workflows * Familiarity with enterprise software and internal platform experiences * Understanding of product strategy and user research methods * Experience building interfaces for data-heavy, workflow-oriented, or highly technical applications * Familiarity with design systems governance and frontend architecture at scale ## Description * Design and build high-quality frontend experiences for VaiDA and related AI-driven enterprise workflows * Lead UX engineering strategy and frontend architecture for VaiDA * Own interaction design and prototyping for a wide spectrum of user journeys and multi-agent experiences * Translate sophisticated technical capabilities into clear, intuitive, and scalable interfaces * Create workflow visualizations that improve usability, clarity, and user confidence * Partner closely with product, engineering, AI, and business stakeholders to define user-centered solutions * Develop and refine reusable UI patterns, components, and design standards for enterprise-scale applications * Prototype and validate concepts quickly to inform product direction and implementation * Advocate for usability best practices and help raise the bar for design quality across digital products * Contribute to the overall product vision for VaiDA as a trusted and engaging enterprise AI experience * Mentor engineers and influence UX engineering best practices across teams, In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. ## Related Videos - [The Resilience of the World Wide Web](https://www.wearedevelopers.com/videos/1281-the-resilience-of-the-world-wide-web) - [Boost Productivity with AI: Figma & Playwright MCP Workflows - Aris Markogiannakis](https://www.wearedevelopers.com/videos/1768-boost-productivity-with-ai-figma-playwright-mcp-workflows-aris-markogiannakis) - [Developing the Backend with Stefan Lingler, CTO at Shpock](https://www.wearedevelopers.com/videos/100360-developing-the-backend-with-stefan-lingler-cto-at-shpock) - [Design Patterns For AI Products in 2026](https://www.wearedevelopers.com/videos/100255-design-patterns-for-ai-products-in-2026) - [Designing the Future of Human<>Agent Collaboration](https://www.wearedevelopers.com/videos/1447-designing-the-future-of-human-agent-collaboration) - [NoLoJS - Avoiding JavaScript Cruft with HTML and CSS - Aaron T. 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