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# Sr. Manager, Manufacturing Execution Systems (MES)

- **Company:** Novartis Group
- **Location:** Durham, NC, United States
- **Experience:** Expert
- **Salary:** $108,500.0 - $201,500.0
- **Contract:** Permanent contract
- **Skills:** Information Systems, Data Integrity, Technical Data Management Systems
- **Published:** August 2, 2026
- **Apply:** https://diversityjobs.com/main/sendform/8/8/28176/1/17789999?backUrl=%2Fcareer%2F17789999%2FSr-Manager-Manufacturing-Execution-Systems-Mes-North-Carolina-Durham

## About the Role

* Bachelor's degree in Biological Sciences, Engineering, Information Systems, Automation, or a related technical field.
 * Minimum eight years of experience in manufacturing systems, MES, automation, or regulated manufacturing environments.
 * Experience within the pharmaceutical or biopharmaceutical industry.
 * Strong knowledge of GMP, FDA regulations, electronic manufacturing systems, and data integrity principles.
 * Demonstrated success leading and developing technical or manufacturing-focused teams.
 * Proven ability to lead complex cross-functional projects within a matrix organization.
 * Excellent verbal and written communication skills with the ability to influence diverse stakeholders.
 * Strong collaboration and relationship-building skills across Manufacturing, Quality, MS&T, Engineering, IT, and Finance.

Desirable Requirements

 * Experience with MES roadmaps, manufacturing data analytics, KPIs, and digital manufacturing transformation initiatives.
 * Experience supporting validation, change control, CAPAs, audit readiness, and regulatory inspections for GMP computerized systems.

## Description

* Lead strategy, governance, and operational oversight for MES across the site.
 * Align MES priorities with manufacturing goals, project commitments, and production readiness requirements.
 * Oversee MES lifecycle management, including support, enhancements, upgrades, and system compliance.
 * Ensure manufacturing systems meet GMP, FDA, data integrity, and quality requirements.
 * Partner across Manufacturing, Quality, Engineering, and IT to resolve complex system challenges.
 * Drive continuous improvement using performance metrics, operational trends, and KPIs.
 * Support 24/7 manufacturing operations through effective MES troubleshooting and issue resolution.
 * Lead cross-functional projects, balancing resources and priorities to deliver business-critical initiatives.
 * Maintain audit-ready systems, documentation, procedures, and compliance practices.
 * Develop high-performing teams through coaching, talent development, and a culture of accountability.


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