> Markdown version of [/jobs/ext/1935837-senior-mes-system-engineer-pharma-hybrid](https://www.wearedevelopers.com/jobs/ext/1935837-senior-mes-system-engineer-pharma-hybrid). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Senior Mes System Engineer | Pharma (Hybrid) - **Company:** Ambit Iberia - **Location:** Madrid, Spain - **Contract:** Permanent contract - **Skills:** Microsoft Windows, Software Documentation, Databases, Linux, Disaster Recovery, Identity and Access Management, PostgreSQL, Citrix Systems, OpenShift, Oracle Databases, Oracle (Applications), System Availability, Containerization, Kubernetes, Information Technology, Operational Systems, GXP, Docker - **Published:** August 5, 2026 - **Apply:** https://www.buscojobs.com.es/senior-mes-system-engineer-pharma-hybrid-en-madrid-ID-365563825 ## About the Role Strong knowledge of IT infrastructure technologies (Windows, Linux, Citrix). Experience with database systems (Oracle, PostgreSQL). Understanding of Operational Technology (OT) environments in pharmaceutical manufacturing. Solid experience working in structured and regulated environments (GxP). Strong analytical and problem-solving skills. Proactive and solution-oriented mindset. Ability to work effectively in international and cross-functional teams. Advanced or fluent English communication skills. Nice to Have Experience with Manufacturing Execution Systems (MES) (preferably Körber PAS-X 3.2 or newer). Knowledge of MBR design and lifecycle management within MES platforms. Experience with containerization technologies (Docker, Kubernetes, OpenShift). Hands?on experience with Docker?based deployments. Experience with Oracle database administration or integration in manufacturing IT systems. 3-5 years of professional experience in production IT systems or engineering environments. ## Description We are looking for anMES Senior Systems Engineerto support and enhance Manufacturing Execution Systems (MES) within a global pharmaceutical environment.In this role, you will ensure the stable operation, continuous improvement, and compliance of MES applications and their technical environments.You will work closely with IT, business stakeholders, and SMEs to maintain high system availability, support change processes, and ensure alignment with GxP standards.Tasks & ResponsibilitiesEnsure day-to-day operations and stability of MES applications and platforms.Execute service requests from IT teams, business users, and stakeholders.Drive continuous improvement initiatives to enhance MES processes and support quality.Test, document, implement, and communicate change requests related to MES applications and environments.Maintain and update application and system documentation.Coordinate and execute testing activities, ensuring proper documentation and evidence.Ensure GxP compliance across operations, access management, and system processes.Manage and coordinate application and infrastructure changes.Analyze system performance, capacity, and scalability, proposing improvements where needed.Perform security and access reviews (Confidentiality, Integrity, Availability).Manage configuration items and periodic system reviews.Oversee user access, license usage, and security controls.Ensure proper execution of technical operations (backup checks, restore tests, disaster recovery, patching, upgrades).Coordinate new demands and requirements with IT stakeholders and SMEs.Provide support during audits, including on-site presence when required.Ensure all training and compliance requirements are fulfilled.Support business hours operations, with occasional planned work outside standard hours.SkillsStrong knowledge of IT infrastructure technologies (Windows, Linux, Citrix).Experience with database systems (Oracle, PostgreSQL).Understanding of Operational Technology (OT) environments in pharmaceutical manufacturing.Solid experience working in structured and regulated environments (GxP).Strong analytical and problem-solving skills.Proactive and solution-oriented mindset.Ability to work effectively in international and cross-functional teams.Advanced or fluent English communication skills.Nice to HaveExperience with Manufacturing Execution Systems (MES) (preferably Körber PAS-X 3.2 or newer).Knowledge of MBR design and lifecycle management within MES platforms.Experience with containerization technologies (Docker, Kubernetes, OpenShift).Hands?on experience with Docker?based deployments.Experience with Oracle database administration or integration in manufacturing IT systems.3-5 years of professional experience in production IT systems or engineering environments.Schedule*****h -*****h from Monday to Friday (flexible)1 day a month on-siteConditionsSalary package based on your profile.We will discuss it on our first call.Permanent ContractTicket restaurant included in-office hoursFlexible Retribution Program (Urban Sports Club)Learning & DevelopmentFriend Referral Program#J-*****-Ljbffr ## Related Videos - [Blueprints for Success: Steering a Global Data & AI Architecture](https://www.wearedevelopers.com/videos/1577-blueprints-for-success-steering-a-global-data-ai-architecture) - [Docker network without Docker](https://www.wearedevelopers.com/videos/1418-docker-network-without-docker) - [ZEISS & Microsoft - Building the Next Generation Medical Ecosystem in the Cloud](https://www.wearedevelopers.com/videos/424-zeiss-microsoft-building-the-next-generation-medical-ecosystem-in-the-cloud) - [Docker Compose: Rediscovered](https://www.wearedevelopers.com/videos/1978-docker-compose-rediscovered) - [Docker exec without Docker](https://www.wearedevelopers.com/videos/1094-docker-exec-without-docker) - [Docker build without Docker](https://www.wearedevelopers.com/videos/100114-docker-build-without-docker) ## Related Articles - [Top-Paying Tech Jobs (with Salaries)](https://www.wearedevelopers.com/magazine/372-top-paying-tech-jobs-with-salaries) - [Spanish Business Culture and Etiquette](https://www.wearedevelopers.com/magazine/353-spanish-business-culture-and-etiquette) - [The Most Popular IT Jobs on the Market](https://www.wearedevelopers.com/magazine/376-the-most-popular-it-jobs-on-the-market) - [The Biggest German Tech Companies](https://www.wearedevelopers.com/magazine/424-the-biggest-german-tech-companies) - [Fully Remote Software Engineer Jobs](https://www.wearedevelopers.com/magazine/447-fully-remote-software-engineer-jobs) - [Finding Jobs in Germany](https://www.wearedevelopers.com/magazine/375-finding-jobs-in-germany)