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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Senior Director, Core Technology Architect - **Company:** Vertex Pharmaceuticals Incorporated - **Location:** Boston, MA, United States (Remote available) - **Experience:** Expert - **Salary:** $228,000.0 - $342,000.0 - **Contract:** Permanent contract - **Skills:** Microsoft Windows, Artificial Intelligence, Microsoft Azure, Microsoft Online Services, Cloud Computing, Cloud Computing Security, Collaborative Software, Cyber Security, Computer Networks, Data as a Services, Data Centers, Integrated Architecture Framework, Information Systems Security Architecture Professional, Network Security, Cloud Services, Zero Trust Network Access, SAP Sales and Distribution, Microsoft SharePoint, User Environment Management, Wide Area Networks, Microsoft Power Automate, IT Architecture, Information Technology, Enterprise Integration, GXP, Cisco, Servicenow - **Published:** August 8, 2026 - **Apply:** https://jobs.localjobnetwork.com/apply/add/87982630/1 ## About the Role * Azurearchitecture and cloud services- AWScloud environments - Microsoft 365ecosystem -Microsoft Teams - Exchange -SharePoint- Microsoft Copilot- Azure AI -Enterprise networking and infrastructure -SD-WAN * Securityarchitecture alignment and experience co-architecting cybersecurity technologies including identity, endpoint protection, network security, zero-trust, and cloud security solutions. * Data center and hybrid hosting * End-user computing acrossWindows,Mac, and mobility platforms * Collaboration technologies includingZoomandTeams Rooms * ServiceNowand ITSM platforms * Architecture governance and standards development * Reference architecture and integration pattern design * Technology lifecycle management and rationalization Preferred Skills * Experience enabling enterprise AI solutions in a regulated environment * Familiarity with digital workplace transformation initiatives * Background in hybrid infrastructure and global collaboration ecosystems * Knowledge of service delivery operating models and managed services integration * Experience improving interoperability across infrastructure, workplace, and support platforms * Strong understanding of compliance, governance, and secure-by-design architecture principles Education and Experience: * 12-15+ years of experience in IT infrastructure and workplace technologies * Proven experience in solution architecture or enterprise architecture leadership roles * Experience operating in complex, global enterprise environments * Demonstrated success working across multiple infrastructure domains simultaneously * Experience inGxP-regulatedenvironments such as biotechnology, pharmaceuticals, or healthcare strongly preferred * Demonstrated ability to lead through influence in a federated organization * Strong executive presence with excellent communication and stakeholder management skills * Ability to translate complex technical concepts into clear business-aligned recommendations * Proven ability to balance strategic architecture with pragmatic execution * Experience collaborating with global vendors, strategic partners, and managed service providers, Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Human Resources at ApplicationAssistance@vrtx.com. ## Description Vertex is seeking aSeniorDirector, Solution Architect - Core Technologyto serve as a senior individual contributor responsible for defining and driving an integrated architecture strategy across infrastructure and collaboration platforms in a global, GxP-regulated biopharma environment. This leader will establish the foundational architecture function within Core Technology and partner closely with domain leaders across cloud, network, collaboration, end-user computing, workplace technology, and service management.Thisrole will ensure that enterprise technologies are cohesive, scalable, secure, and compliant, while helping shape a unified AI and digital workplace strategy across Microsoft 365, cloud platforms, and end-user environments. This role will partner closely with Information Security to co-architect cybersecurity capabilities across the Core Technology ecosystem and drive alignment between infrastructure, collaboration, and security architecture strategies to ensure secure, scalable, and compliant technology solutions. Key Duties and Responsibilities: Enterprise Integration & Architecture Strategy * Define and drive end-to-end solution architecture across Core Technology domains, including: * Cloud platforms, with anAzure-firststrategy and existingAWSfootprint * Microsoft 365 ecosystem, includingTeams, Exchange, SharePoint, and Copilot enablement * Enterprise network services, including connectivity,SD-WAN, and global infrastructure * Data center and hybrid hosting environments * End-user computing acrossWindows, Mac, and mobility * Conference room and workplace collaboration technologies, includingZoomandTeams Rooms * ITSM and service experience platforms, includingServiceNow * Partner with Information Security to co-architect and integrate cybersecurity platforms and controls across cloud, network, workplace, collaboration, and end-user computingdomains, ensuring alignment with Core Technology referencearchitecture, operational models, and enterprise risk requirements. * Partner with Information Security to establish shared architecture principles, technology standards, integration patterns, and governance processes that align infrastructure, collaboration, and securityarchitectureacross the enterprise * Create reference architectures, design standards, and integration patterns across technology domains * Eliminate silos and ensure interoperability across Core Technology services * Drive scalable and sustainable architectural approaches that support global business needs AI & Digital Workplace Enablement * Lead Core Technology architecture strategy to enable enterprise AI capabilities * Support AI enablement within: * The Microsoft ecosystem, includingCopilot, Microsoft 365, and Azure AI * End-user productivity and collaboration platforms * Ensure AI-related solutions are securely integrated across infrastructure layers * Partner with Security and Data teams to align AI architecture with governance, privacy, and regulatory expectations * Help shape a seamless and secure digital workplace experience for employees globally Architecture Governance & Standards * Partner with Information Security to establish shared architecture principles, technology standards, integration patterns, and governance processes that align infrastructure, collaboration, and security architectures across the enterprise * Establish architecture governance processes, including: * Design reviews * Technology standards * Exception management * Serve as the central point of accountability for cross-domain architectural decisions * Ensure alignment withGxP, regulatory, compliance, and security requirements * Drive lifecycle management, rationalization, and modernization of Core Technology platforms Cross-Functional Leadership & Influence * Operate as a peer to Directors across Network, Cloud, EUC, Collaboration, and related domains. * Serve as the primary Core Technology architecture partner to Information Security, driving joint architecture reviews, technology evaluations, integration decisions, and long-term platform strategy. * Influence technical direction across a federated organization without direct authority * Partner closely with Information Security, Data Services, and Application teams to define and maintain a unified infrastructure, collaboration, and security architecture strategy and roadmap. * Act as a trusted advisor to senior DTE leadership on technology strategy, investments, and roadmap decisions * Balance strategic vision with practical execution to accelerate business value Vendor & Partner Alignment * Shape architecture strategy in partnership with key vendors and service providers, including: * Microsoft(Azure, M365) * Cisco, Palo Alto, Verizon, AT&T(network and security) * Zoom(collaboration) * ServiceNow(ITSM) * Accenture(managed services and operations) * Lenovo, Dell, Apple(end-user computing) * Ensure third-party solutions align with enterprise architecture standards and long-term technology strategy * Support effective vendor collaboration to deliver secure, compliant, and high-performing services Operational Alignment * Ensure solutions are designed for operability in partnership with outsourced operations teams * Drive consistency between architecture and service delivery models, including Service Desk and Deskside Support * Improve end-user experience, supportability, and reliability through cohesive technical design, In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. ## Related Videos - [Blueprints for Success: Steering a Global Data & AI Architecture](https://www.wearedevelopers.com/videos/1577-blueprints-for-success-steering-a-global-data-ai-architecture) - [Applying Agile Principles to Incident Management ](https://www.wearedevelopers.com/videos/101-applying-agile-principles-to-incident-management) - [How Cisco embraced a DevOps culture within its network engineering team](https://www.wearedevelopers.com/videos/99-how-cisco-embraced-a-devops-culture-within-its-network-engineering-team) - [ZEISS & Microsoft - Building the Next Generation Medical Ecosystem in the Cloud](https://www.wearedevelopers.com/videos/424-zeiss-microsoft-building-the-next-generation-medical-ecosystem-in-the-cloud) - [AI in Production: applied AI & enterprise use cases](https://www.wearedevelopers.com/videos/100130-ai-in-production-applied-ai-enterprise-use-cases) - [Computer Vision from the Edge to the Cloud done easy](https://www.wearedevelopers.com/videos/263-computer-vision-from-the-edge-to-the-cloud-done-easy) ## Related Articles - [What Are The Top Skills Required For Azure Developers?](https://www.wearedevelopers.com/magazine/77-what-are-the-top-skills-required-for-azure-developers) - [Fully Remote Software Engineer Jobs](https://www.wearedevelopers.com/magazine/447-fully-remote-software-engineer-jobs) - [6 Emerging Technologies We’ll Learn About in 2025](https://www.wearedevelopers.com/magazine/381-6-emerging-technologies-we-ll-learn-about-in-2025) - [Résumé-Driven Development: How IT trends affect the job market for software developers](https://www.wearedevelopers.com/magazine/59-resume-driven-development-how-it-trends-affect-the-job-market-for-software-developers) - [Dev Digest 121 - AI goes offline](https://www.wearedevelopers.com/magazine/456-dev-digest-121-ai-goes-offline) - [Navigating the AI Shift](https://www.wearedevelopers.com/magazine/629-navigating-the-ai-shift)