> Markdown version of [/jobs/ext/1993537-director-oncology-data-science](https://www.wearedevelopers.com/jobs/ext/1993537-director-oncology-data-science). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Director, Oncology Data Science - **Company:** CareerCircle - **Location:** San Francisco, CA, United States - **Salary:** $194,100.0 - $305,600.0 - **Contract:** Permanent contract - **Skills:** Artificial Intelligence, Algorithm Design, Amazon Web Services, Data Analysis, Bioinformatics, Cloud Computing, Computational Biology, Computer Simulation, Image Analysis, Directed Acyclic Graph (Directed Graphs), Information Engineering, Data Infrastructure, Data Mining, Data Visualization, Data Warehousing, Linux, R (Programming Language), Statistical Hypothesis Testing, Python (Programming Language), Machine Learning, Scientific Computating, Software Engineering, Transfer Learning, Deep Learning, Electronic Medical Records, Git, Information Technology, Data Analytics, Software Version Control - **Published:** August 8, 2026 - **Apply:** https://www.careercircle.com/jobs/all/all/usa/ma/boston/47ac7dd9-757f-414c-a64d-19155cf8f56e ## About the Role Research Biopsies Innovation Algorithms Biomarkers Statistics Compassion Proteomics Data Mining Data Science Communication Data Analysis Presentations Biotechnology Cancer Biology Bioinformatics Pharmaceuticals Detail Oriented Clinical Trials Medical Records Cloud Computing Cancer Genomics Drug Development Machine Learning Telephone Skills Digital Pathology Influencing Skills Biochemical Assays Applied Mathematics, * Master's (with 12+ years) or Ph.D. (with 8+ years) in Engineering, Applied Mathematics, Bioinformatics, Computational Biology or related field with a significant computational and statistical expertise and relevant experience in a pharma, biotech or academic setting., * Extensive experience applying computational methods in cancer biology. * Extensive experience and demonstrated expertise with scientific cloud-based computation environments (R/Python highly preferred). * AI/ML exposure and experience including supervised and unsupervised machine learning, foundation models, and modern coding. * Experience with genomic datasets across cancer types and therapeutic modalities with proven expertise in drug development pipeline impact. * Hands-on analysis experience with algorithms for large genetic, genomic, immunogenomic and clinical datasets (e.g. TCGA, GTEx, DepMap, CPTAC) as well as RWD genomic, imaging and EHR datasets. * Experience with leading a team of highly performing computational scientists. * Strong communication and presentation skills; ability to guide and influence decisions through use of data-driven hypotheses; attention to detail; * Independent, flexible and collaborative mindset. Preferred Experience and Skills: * Proven experience with analysis of genomic data originating from clinical trials. * Exposure and experience with companion diagnostic development, preferably for NGS. * Understanding of the major concepts of cancer biology as represented in molecular data. * Expert knowledge of methods of statistical learning and data mining and application to biological problems. * Experience with a matrix environment and ability to effectively collaborate with colleagues from a wide range of disciplines. * Record of publishing in high profile scientific journals. #EligibleforERP, Artificial Intelligence (AI), Cancer Genomics, Cancer Research, Cloud Computing, Computational Methods, Data Science, Genomic Data Analysis, Machine Learning (ML), Multimodal, Multimodal Analysis, Oncology, Cambridge, MA*On-Site Linux Triage Tooling Biology Research Genetics Genomics Pipelines Mentorship Innovation Immunology Statistics Compassion Proteomics Mathematics Scalability Phenotyping Data Science Communication Biostatistics Data Modeling Deep Learning Cell Cultures Prioritization Drug Discovery Bioinformatics Image Analysis Version Control Cloud Computing Small Molecules Disease Biology Computer Science Algorithm Design Machine Learning Telephone Skills Data Engineering, Data Warehousing Influencing Skills Predictive Modeling Contingent Workforce Scientific Computing Computational Biology Artificial Intelligence Pre-Clinical Development Machine Learning Algorithms Ribonucleic Acid Sequencing Statistical Learning Theory Influencing Without Authority ## Description Molecular Diagnostics, Computational Biology Therapeutic Modalities Artificial Intelligence Pre-Clinical Development R (Programming Language) Ribonucleic Acid Sequencing Statistical Learning Theory Python (Programming Language) Influencing Without Authority, The Translational Genome Analytics group within the Data, AI & Genome Sciences Department is recruiting a Director of Oncology Biomarker Discovery to join an oncology data science team dedicated to advancing our company's vast and expanding oncology pipeline, with a focus on multimodal biomarker discovery, validation, and implementation. The successful candidate will: * Investigate proprietary and public real-world molecular datasets and clinical trials in conjunction with tissue and periphery assays with a goal of identifying robust multimodal biomarkers of response and resistance to an array of cancer therapies across indications and lines of therapy, with line of sight to diagnostic development. * Leverage advanced AI/ML approaches to integrate multi-modal data including RNAseq, WES, ctDNA, digital pathology, proteomics, immune activation assays, and liquid biopsies to discover biomarkers and molecularly defined groups of patients as well as molecular mechanisms of modulation of therapeutic response reflected in longitudinal analytes. * Effectively present data analyses to inform and interact with stakeholders representing a wide span of internal organizations, including Translational Oncology, Molecular Diagnostics, Clinical Development, Statistics, Therapeutic Area Biology, and Commercial Development., Oncology Research Biopsies Innovation Algorithms Biomarkers Statistics Compassion Proteomics Data Mining Data Science Communication Data Analysis Presentations Biotechnology Cancer Biology Bioinformatics Pharmaceuticals Detail Oriented Clinical Trials Medical Records Cloud Computing Cancer Genomics Drug Development Machine Learning Telephone Skills Digital Pathology Influencing Skills Biochemical Assays Applied Mathematics Contingent Workforce Molecular Diagnostics Computational Biology Therapeutic Modalities Artificial Intelligence Pre-Clinical Development R (Programming Language) Ribonucleic Acid Sequencing Statistical Learning Theory Python (Programming Language) Influencing Without Authority +0 Associate Director, Functional Genomics, Data Science Merck & Co., Inc, Transfer Learning Edge Intelligence Biopharmaceuticals Data Visualization Workflow Management Amazon Web Services Data Infrastructure Experimental Design Functional Genomics Software Engineering Software Development Contingent Workforce Computational Biology Artificial Intelligence Statistical Programming Relationship Management Research And Development R (Programming Language) Applied Machine Learning Ribonucleic Acid Sequencing Git (Version Control System) Python (Programming Language) Statistical Hypothesis Testing Directed Acyclic Graph (Directed Graphs) +0 Google IT Automation with Python ## Related Videos - [Data Science on Software Data](https://www.wearedevelopers.com/videos/162-data-science-on-software-data) - [How a Small Team Shrank a Microsoft Monorepo by 94%](https://www.wearedevelopers.com/videos/1236-how-a-small-team-shrank-a-microsoft-monorepo-by-94) - [Docker network without Docker](https://www.wearedevelopers.com/videos/1418-docker-network-without-docker) - [Geometric deep learning for drug discovery](https://www.wearedevelopers.com/videos/264-geometric-deep-learning-for-drug-discovery) - [Blueprints for Success: Steering a Global Data & AI Architecture](https://www.wearedevelopers.com/videos/1577-blueprints-for-success-steering-a-global-data-ai-architecture) - [Git for Code Reviews](https://www.wearedevelopers.com/videos/429-git-for-code-reviews) ## Related Articles - [Coffee with Developers - Maria Apazoglou - Making AI understandable for all in production](https://www.wearedevelopers.com/magazine/475-coffee-with-developers-maria-apazoglou-making-ai-understandable-for-all-in-production) - [The Fastest-Growing Tech Sectors to Look Out for in 2025](https://www.wearedevelopers.com/magazine/373-the-fastest-growing-tech-sectors-to-look-out-for-in-2025) - [How to Become an AI Engineer](https://www.wearedevelopers.com/magazine/331-how-to-become-an-ai-engineer) - [Résumé-Driven Development: How IT trends affect the job market for software developers](https://www.wearedevelopers.com/magazine/59-resume-driven-development-how-it-trends-affect-the-job-market-for-software-developers) - [Navigating the AI Shift](https://www.wearedevelopers.com/magazine/629-navigating-the-ai-shift) - [Graph and AI Trends 2026: Why Is AI Running but Not Yet Delivering?](https://www.wearedevelopers.com/magazine/680-graph-and-ai-trends-2026-why-is-ai-running-but-not-yet-delivering)