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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Senior Manufacturing Systems Engineer DeltaV - **Company:** Amgen - **Location:** Holly Springs, NC, United States - **Experience:** Expert - **Contract:** Permanent contract - **Skills:** Fieldbus, Network Planning and Design, Profibus, Systems Integration, VMware Infrastructure, Iq/oq/pq, Information Technology, Process Control Systems - **Published:** August 26, 2026 - **Apply:** https://www.biospace.com/logon?PipelinedPage=%2Fjob%2F3070574%2Fsenior-manufacturing-systems-engineer-deltav%3FAction%3DContinueJobApplication%23application-form ## About the Role * High School Diploma / GED and 10 years of Engineering experience OR * Associates Degree and 8 years of Engineering experience OR * Bachelors Degree and 4 years of Engineering experience OR * Masters Degree and 2 years of Engineering experience OR * Doctorate Degree Preferred Qualifications: * Degree in Electrical Engineering or Computer Science, ChemicalEngineeringorBiotech Engineering. * Extensive experience with EmersonDeltaV, Process Control Network design including network segregation, Process Control Systems: Virtual Infrastructure design and implementation, System Integration using OPC, Foundation Fieldbus, and Profibus. * Direct knowledge of integrating various OEM automation software and field instrumentation technologies. * Direct knowledge of Automation System design, experience in Process control engineering and troubleshooting with GMP biopharmaceutical production facility equipment/systems automation. * Experiencewith upstream/downstream/solution prepunit operations such as media, harvest, mixers, bioreactors, chromatography, viral filtration and ultrafiltration/diafiltrationamong others. * Extensive understanding and background in programming, design, installation and lifecycle management of manufacturing process controls,automationand field instrumentation technologies. * In-depth knowledge of industry standards such as 21 CFR Part 11, ASTM 2500, S88, S95, GAMP, GDP, and GMP. * Experience in Capital Project Lifecycle Management including conceptual design, basis of design, detailed design, implementation, and validation. * The ideal individual must be a self-directed team player ready to mentor and develop engineering staff and embrace a team-based culture that relies on collaboration for effective decision-making. * Strong leadership, technical writing, and communication/presentation skills. ## Description In this vital role as a member of the Facilities & Engineering (F&E) group, you will lead technical projects, and drive innovation and support manufacturings upstream, downstream, and solution preparation automation needs.You will solve complex engineering problems and ensure the company's engineering efforts align with strategicobjectives. You will also provide leadership and guidance to the Automation Engineering team supporting 24/7 manufacturing and facility operations. You will partner closely with the capital project team to design, build, commission, andqualifynew equipment and systems needed for drug substance production. This role will develop domainexpertiseto support operations upon start-up, focusing on manufacturing automation. Job responsibilities include: * Site design, construction, start-up, and operational readiness: * Provide support to the capital project team with a strong focus on safety and on-time facility start-up. * Collaborate with the site process engineering team to understand key process requirements and develop process control automation solutions primarilyutilizingEmersonDeltaVDistributed Control System (DCS) forupstream, downstream, and/or solution prepoperations. * Support commissioning and qualification efforts including Automation Installation Verification/Automation Check Out (IV/ACO). * Partner with various organizational units to support tasksincluding operational readiness, document reviews, deviationinvestigationand change controls. * Develop andmaintaindetailed specifications,SOPsand operating standards thatimpactmultiple organizational units. * Provide mentoring to develop and accelerate site technical automation capabilities. * Site Operations: * Act as system owner forUpstream,Downstream, and/or Solution prepAutomation processes. * Manage Day-to-day Operational Support including:24 x 7 Onsite/On Call Operational Support, Troubleshooting Support to Plant and Mfg. Operations, Process and Utility Automaton systems, andAutomation Systemspare parts management * Lead and support functional area projects focused on improving processequipment/utilities/facilitiesas well as capital projects to integrate new drug substance manufacturing technologies into the facility. * Lead and support technical root cause analysis, incident investigations, andtroubleshooting onprocess control issues related to plant operations. * Lead and support new product introductions (NPI) ornew technologyintroductions by performingautomationengineering assessments, implementingautomationsystem configurationchangesand supporting engineering and process qualification runs as applicable. * Prepare and review Standard Operating Procedures (SOP) and cGMP documents., In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards. ## Related Videos - [Remote Driving on Plant Grounds with State-of-the-Art Cloud Technologies](https://www.wearedevelopers.com/videos/251-remote-driving-on-plant-grounds-with-state-of-the-art-cloud-technologies) - [More efficient software for more efficient microchips](https://www.wearedevelopers.com/videos/1164-more-efficient-software-for-more-efficient-microchips) - [How to Domain Model – An example from manufacturing](https://www.wearedevelopers.com/videos/742-how-to-domain-model-an-example-from-manufacturing) ## Related Articles - [How We Built a Worry-Free System That Runs for 10+ Years – And What We’d Do Again](https://www.wearedevelopers.com/magazine/751-how-we-built-a-worry-free-system-that-runs-for-10-years-and-what-we-d-do-again) - [Now is the time for industrialized software development](https://www.wearedevelopers.com/magazine/601-now-is-the-time-for-industrialized-software-development) - [Highest Paying Tech Companies for Developers](https://www.wearedevelopers.com/magazine/220-highest-paying-tech-companies-for-developers) - [Where To Find Software Engineering Jobs](https://www.wearedevelopers.com/magazine/396-where-to-find-software-engineering-jobs) - [Where to Find Entry-Level Software Engineering Jobs](https://www.wearedevelopers.com/magazine/397-where-to-find-entry-level-software-engineering-jobs) - [How to Write a CV and Interview if You Don't Fully Qualify For The Job](https://www.wearedevelopers.com/magazine/183-how-to-write-a-cv-and-interview-if-you-don-t-fully-qualify-for-the-job)