> Markdown version of [/jobs/ext/2249463-principal-enterprise-architect](https://www.wearedevelopers.com/jobs/ext/2249463-principal-enterprise-architect). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Principal Enterprise Architect - **Company:** AstraZeneca - **Location:** Madrid, Spain - **Contract:** Permanent contract - **Skills:** Artificial Intelligence, Cloud Computing, Machine Learning, Computer Networking Systems, Data Analytics, Virtual Agents - **Published:** August 26, 2026 - **Apply:** https://astrazeneca.eightfold.ai/careers/job/563877690540267?domain=astrazeneca.com ## About the Role Ready to make an impact in your career? If you're passionate, growth-orientated and a true team player, we'll help you succeed. Here are some of the skills and capabilities we look for., Seize ownership and excel with autonomy to enjoy the constant rush of ground-breaking discovery. Your ability to anticipate sudden shifts and adapt swiftly will prove critical as you make your mark in an environment that rewards initiative and resilience., Essential Skills/Experience:- Relevant technical degree or equivalent- Experience as an enterprise architect authoring and completing architecture roadmaps- Experience producing application strategies/roadmaps for a global enterprise- Experience with rationalisation, consolidation, and integration of technology across business domains- Experience with large justification phase work - product evaluation, case formulation- Experience developing and influencing business strategies with multi-functional team impact- Experience developing and leading innovative solutions- Proven experience of leading change and challenging approaches/ideas- Experience developing and managing relationships with third-party suppliers- Experience designing complex technology solutions aligned to enterprise roadmaps- Experience in designing AI/ML solutions- Strong networking skills with good internal/external links- Strong communication, facilitation, and relationship-building skills- Ability to interpret and communicate technical information into business language- Awareness of marketplace developments and their relevance to AZ- Ability to work well in diverse, multinational teams and influence others positively- Open mind to learning new skills and capabilities- Ability to follow agile and incremental architecture approaches- Strong analytical skills on architecture trade-offs Desirable Skills/Experience:- Demonstrate initiative, strong customer orientation, and cross-cultural working- People development experience- Budget management experience- Masters or equivalent experience and/or professional certification- Experience in sustainability initiatives in large organizations- Good understanding of industry technology trends regarding Agentic AI- Good eye for business- Understanding of the pharmaceutical/healthcare industry When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. AstraZeneca offers an environment where technical skills meet emotional intelligence. Join a team of highly qualified professionals who are persuasive communicators with empathy. We focus on the human impact of changes we drive, leading to complete solutions for the business. With the freedom to explore innovative technologies, there's never a dull moment as you create a significant footprint through continuous learning and growth. ## Description Here, the answers aren't always available. So, you'll need to bring a fearless, self-starter mindset to navigate uncharted territories. You'll harness your ceaseless energy to discover and make the necessary connections with colleagues to shape the future and achieve maximum impact., Are you ready to inspire change and make a significant impact? At AstraZeneca, we are committed to delivering life-changing medicines while embedding sustainability into every aspect of our work. As a Principal Enterprise Architect in Sustainability, you will play a pivotal role in ensuring our architecture decisions align with both business ambitions and IT strategy. This position is focused on strategic planning over a 1-5 year horizon, as well as immediate solution design projects. You will be instrumental in developing architecture standards, technology strategies, and roadmaps that support our mission to tackle the biggest sustainability challenges of our time. Accountabilities:As a Principal Enterprise Architect, you will:- Provide enterprise design thinking and support across various domains of architecture including Business, Application, Integration, Cloud, Data & Analytics, and AI/ML.- Lead efforts to ensure architecture decisions support business and IT strategy, ensuring compliance with AZ standards, blueprints, and roadmaps.- Participate in architecture assessments and reviews, contributing as a lead reviewing architect or domain expert.- Document and share knowledge and standard methodologies to develop the architecture capability and practice.- Be accountable for developing architecture standards, technology domain strategies, roadmaps, and blueprints.- Define and update 'Transition' and 'To-Be' architectures applying AZ guiding principles.- Support solution development efforts from portfolios, participate in IT initiatives, and provide guidance for better planning and decision-making.- Maintain a view of current and future state architecture within defined focus areas.- Develop architecture building blocks to support enterprise architecture implementation.- Lead or actively participate in enterprise domain teams and working groups., Your wellbeing means a lot to us, and we're here to support you through all of life's ups and downs. That's why we offer an unpaid leave policy, annual leave, reduced-hours timetables and a host of benefits, including a retirement plan, long service award, and health and travel insurance. ## Related Videos - [PySpark - Combining Machine Learning & Big Data](https://www.wearedevelopers.com/videos/44-pyspark-combining-machine-learning-big-data) - [Guiding Agentic AI with Vue](https://www.wearedevelopers.com/videos/2033-guiding-agentic-ai-with-vue) - [Green Cloud Computing](https://www.wearedevelopers.com/videos/592-green-cloud-computing) - [Blueprints for Success: Steering a Global Data & AI Architecture](https://www.wearedevelopers.com/videos/1577-blueprints-for-success-steering-a-global-data-ai-architecture) - [AI in Leadership: How Technology is Reshaping Executive Roles](https://www.wearedevelopers.com/videos/1705-ai-in-leadership-how-technology-is-reshaping-executive-roles) - [How Data is Shaping our Games](https://www.wearedevelopers.com/videos/176-how-data-is-shaping-our-games) ## Related Articles - [Coffee with Developers - Maria Apazoglou - Making AI understandable for all in production](https://www.wearedevelopers.com/magazine/475-coffee-with-developers-maria-apazoglou-making-ai-understandable-for-all-in-production) - [Navigating the AI Shift](https://www.wearedevelopers.com/magazine/629-navigating-the-ai-shift) - [Spanish Business Culture and Etiquette](https://www.wearedevelopers.com/magazine/353-spanish-business-culture-and-etiquette) - [How to Become an AI Engineer](https://www.wearedevelopers.com/magazine/331-how-to-become-an-ai-engineer) - [What Industries Outside of AI Are Hiring The Most AI Experts?](https://www.wearedevelopers.com/magazine/98-what-industries-outside-of-ai-are-hiring-the-most-ai-experts) - [The 12 Best Jobs for Software Engineers](https://www.wearedevelopers.com/magazine/401-the-12-best-jobs-for-software-engineers)