> Markdown version of [/jobs/ext/2270425-principal-data-manager](https://www.wearedevelopers.com/jobs/ext/2270425-principal-data-manager). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Principal Data Manager - **Company:** Travere Therapeutics, Inc. - **Location:** New York, NY, United States (Remote available) - **Salary:** $116,000.0 - $151,000.0 - **Contract:** Permanent contract - **Skills:** Artificial Intelligence, Clinical Data Management, Clinical Data Repository, Databases, Data Transmissions, Data Management - **Published:** August 27, 2026 - **Apply:** https://diversityjobs.com/main/sendform/8/8/28176/1/18082686?backUrl=%2Fcareer%2F18082686%2FPrincipal-Data-Manager-New-York-New-York ## About the Role * Demonstrated knowledge of drug development and Clinical Data Management processes and capable of providing guidance to peers. * Experienced in designing clinical trials utilizing CDASH and SDTM standard terminology. * Understanding of ICH Guidelines and GCP Requirements. * Excellent communication skills and interpersonal skills. * Well-versed in different EDC Systems; preferred proficiency in Medidata RAVE. * Experience in managing outsourced studies and/or leading CRO data management teams * Experience in leading data integrations using EDC, IRT, ePRO and external laboratory processing and vendor reconciliation. * Experience in solving complex and increasingly difficult problems by taking appropriate corrective action and implementing improvements. * Ability to leverage AI Models to support evolving data efficiencies is preferred. * Ability to develop and maintain timelines. * Understanding of dictionary coding (i.e. MedDRA and WHODrug) * Self-motivated and can independently manage responsibilities with minimal supervision. * Demonstrates project management skills (i.e. plan, organize, and manage activities to deliver specific study goals and objectives to measurable targets). * Demonstrate initiative, sound judgement, and flexibility; possess effective time management and organizational skills; and capable of working on multiple projects simultaneously under tight timelines or heavy stress. * Demonstrates ability to interact professionally with personnel at all levels within and external to the company, be dependable and provide support as a team player. * Accountability - Even in ambiguous circumstances, always demonstrate ownership for decisions and actions. * Ability to travel as necessary (approximately 10%). * All positions have an essential job function to be able to perform face to face work with colleagues and/or onsite in San Diego. No role is expected to be 100% remote. ## Description We are seeking a Principal Data Manager with exceptional attention to detail who will be responsible for overseeing the start-up and execution of clinical trials when partnering with a CRO or in-house to ensure data quality and integrity. The individual will perform a variety of complex tasks to ensure complete, accurate, high quality, and regulatory compliant data in support of publications and regulatory submissions., * Act as the single point of accountability for data management deliverables at an assigned level within a given clinical development program. * Serve as Lead CDM to manage and provide daily oversight of CROs and third-party vendors in relation to DM to ensure successful clinical trial implementation and execution to completion. * Serve as a Lead CDM to manage and complete all data management deliverables when sourced internally. * Manage system integrations across data platforms. * Ensure CRO and third-party data review outputs are reviewed according to agreed plans and filed in the Trial Master Plan as appropriate. * Perform ongoing data review of clinical data to identify data discrepancies, general data trends, and corresponding resolutions. * Review data for protocol deviation identification, dictionary coding, and perform user acceptance testing of database. * Review documents produced by vendors and other departments. * Create data management process documents such as data management plans, data review specifications, data transfer agreements, diagram workflows, timelines and communication plans. * Work cross-functionally with other departments within the company assessing and understanding their needs and attend clinical trial project team meetings as lead CDM. * Strategize and plan for database locks and multiple deliverables across numerous studies within a program ensuring consistency in process. * Provide input on the development of standard operating procedures (SOPs) and study protocols from a data management perspective. * Use Artificial Intelligence (AI) models to increase productivity. * Provide guidance to clinical data management personnel on assigned projects. * Set-up, maintain and archive data management related project documentation (i.e., Data Management Plan, CRF Completion Guidelines, etc.). * Independently monitor own activities and project status for successful project deliverables according to timelines. * Adhere to budgets and timelines. * Ensure project is in reasonable state of inspection readiness and compliance. * Additional duties assigned as needed. ## Related Videos - [Kubernetes and Microservices with Multi-Model Databases](https://www.wearedevelopers.com/videos/382-kubernetes-and-microservices-with-multi-model-databases) - [It's all about the Data](https://www.wearedevelopers.com/videos/425-it-s-all-about-the-data) - [Why make use of an integration platform in today's software developments and infrastructure?](https://www.wearedevelopers.com/videos/758-why-make-use-of-an-integration-platform-in-today-s-software-developments-and-infrastructure) - [Data Science, ML & AI in the Oil and Gas Industry at NDT Global - Dr. Katja Träumner](https://www.wearedevelopers.com/videos/1308-data-science-ml-ai-in-the-oil-and-gas-industry-at-ndt-global-dr-katja-traumner) - [Fault Tolerance and Consistency at Scale: Harnessing the Power of Distributed SQL Databases](https://www.wearedevelopers.com/videos/1146-fault-tolerance-and-consistency-at-scale-harnessing-the-power-of-distributed-sql-databases) - [A Hitchhiker's Guide to Resource Efficient Software](https://www.wearedevelopers.com/videos/1414-a-hitchhiker-s-guide-to-resource-efficient-software) ## Related Articles - [The Biggest German Tech Companies](https://www.wearedevelopers.com/magazine/424-the-biggest-german-tech-companies) - [Coffee with Developers - Maria Apazoglou - Making AI understandable for all in production](https://www.wearedevelopers.com/magazine/475-coffee-with-developers-maria-apazoglou-making-ai-understandable-for-all-in-production) - [Résumé-Driven Development: How IT trends affect the job market for software developers](https://www.wearedevelopers.com/magazine/59-resume-driven-development-how-it-trends-affect-the-job-market-for-software-developers) - [Fully Remote Software Engineer Jobs](https://www.wearedevelopers.com/magazine/447-fully-remote-software-engineer-jobs) - [Highest Paying Tech Companies for Developers](https://www.wearedevelopers.com/magazine/220-highest-paying-tech-companies-for-developers) - [Navigating the AI Shift](https://www.wearedevelopers.com/magazine/629-navigating-the-ai-shift)