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# Senior Principal Data Scientist

- **Company:** Novartis
- **Location:** London, UK
- **Experience:** Expert
- **Salary:** £57,050.0 - £105,950.0
- **Contract:** Permanent contract
- **Skills:** Artificial Intelligence, Data Analysis, Bash Shell, Computer Programming, Data Cleansing, Data Transformation, Data Visualization, R (Programming Language), Python (Programming Language), Machine Learning, SQL Databases, Unstructured Data, Random Forest, Deep Learning, Pandas, Data Pipelines
- **Published:** August 27, 2026
- **Apply:** https://uk.indeed.com/viewjob?jk=322e1bb1df458bd2

## About the Role

* Master's degree or Ph.D. in data science, biostatistics, or other quantitative field (or equivalent).
 * Experience in clinical drug development with extensive exposure to clinical trials.
 * Strong knowledge and understanding of statistical methods such as time to event analysis, machine learning, meta-analysis, mixed effect modeling, longitudinal modeling, Bayesian methods, variable selection methods (e.g., lasso, elastic net, random forest), design of clinical trials.
 * Strong programming skills in R and Python. Demonstrated knowledge of data visualization, exploratory analysis, and predictive modeling.
 * Excellent interpersonal and communication skills (verbal and writing)
 * Ability to develop and deliver clear and concise presentations for both internal and external meetings in key decision-making situations.

## Description

As a Senior Principal Data Scientist in the Medical Affairs Advanced Quantitative Sciences group, you will be responsible for the discussion and implementation of data science methodologies applied to patient-level data (including various clinical, real-world, and biomarker data) across clinical development. You will combine your data science and AI skills and your scientific knowledge in biology or medicine or statistics to enrich drug development decisions in close collaboration with internal and external partners., * You will contribute to planning, execution, interpretation, validation and communication of innovative exploratory analyses and algorithms, to facilitate internal decision making

 * You will provide technical expertise in data science and (predictive) machine learning/AI to identify opportunities for influencing internal decision making as well as discussions on white papers/regulatory policy.
 * You will perform hands-on analysis of integrated data from clinical trials and the real world to generate fit-for-purpose evidence that is applied to decision making in drug development programs.
 * Translate business questions into analytical problems and build solutions using visualization techniques, dashboards, machine and deep learning, and statistical modelling.
 * Search and develop new algorithms, methods, statistical models and business models, providing insight into structured and unstructured data.
 * Apply R-based analytical and statistical techniques to solve business problems
 * Applying data cleaning, wrangling, and analysis techniques using tools like AI, R, Python and Pandas.
 * Developing and managing data pipelines using tools like AI, R, Python, Bash, and SQL.


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