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# Bioprocess Applications Engineer 3

- **Company:** Merck KGaA
- **Location:** Bedford, MA, United States
- **Experience:** Experienced
- **Salary:** $84,900.0 - $127,300.0
- **Contract:** Permanent contract
- **Skills:** Business Analytics Applications, Application Notes, Software Documentation, Data Integrity, Software Engineering
- **Published:** August 3, 2026
- **Apply:** https://www.indeed.com/viewjob?jk=f246f6062953fea7

## About the Role

* Ph.D. in Chemical Engineering, Mechanical Engineering, Biochemical Engineering or other engineering discipline, * Master's degree in Chemical Engineering, Mechanical Engineering, Biochemical Engineering or other engineering discipline AND 4+ years of industry experience, * Bachelor's degree in a Chemical Engineering, Mechanical Engineering, Biochemical Engineering or other engineering discipline AND 5+ years of industry experience, * Experience in biopharmaceutical process development, PAT implementation, or analytical method development in a biomanufacturing context, with a demonstrated track record of leading technical projects to completion
 * Technical expertise and hands-on experience with PAT sensors, inline spectroscopy (e.g., Raman), chemometric model development, process automation, and downstream biomanufacturing unit operations
 * Experience leading projects of moderate to extended complexity, driving results and meeting milestones with excellent problem-solving skills, a collaborative mindset, and strong adherence to data integrity and cGMP documentation standards
 * Ability to communicate effectively with peers, customers, vendors, and stakeholders through written technical reports, oral presentations, timely discussions and experience mentoring junior engineers
 * Ability to apply engineering and scientific principles to resolve technical challenges of extended scope and complexity, with the ability to translate analytical insights into actionable process improvements and strategic recommendations

## Description

* Integrate PAT sensors and inline spectroscopy into downstream unit operations, including Protein A chromatography, UF/DF, and other mAb purification steps
 * Lead development, optimization, and lifecycle management of Raman chemometric models for mAb streams, buffers, and excipients
 * Oversee qualification, deployment, and lifecycle support of Raman instruments and inline sensing units, including model transfer and qualification activities
 * Identify and address customer PAT performance gaps, competitive technology landscapes, and process design targets through data-driven solutions and strategic recommendations
 * Drive technical strategy in inline spectroscopy, advanced process control, and digitalization of process and analytical tools
 * Lead cross-functional contributions spanning R&D, Manufacturing, Quality, Sales, and Product Management to commercialize PAT and digital solutions
 * Produce customer-facing technical content, including application notes, technical guides, and webinars
 * Support customer trials and investigations; capture actionable feedback to inform product and application development


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