> Markdown version of [/jobs/ext/2708692-ai-applications-engineer](https://www.wearedevelopers.com/jobs/ext/2708692-ai-applications-engineer). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # AI Applications Engineer - **Company:** Twin Health - **Location:** United States (Remote available) - **Experience:** Expert - **Salary:** $195,000.0 - $210,000.0 - **Contract:** Permanent contract - **Skills:** Java (Programming Language), Artificial Intelligence, Software Applications, Python (Programming Language), PostgreSQL, MySQL, Query Optimization, Software Engineering, SQL Databases, Systems Integration, Large Language Models, Multi-Agent Systems, Prompt Engineering, Spring-boot, Generative AI, Backend, Information Technology, Api Design, GPT, Microservices - **Published:** September 4, 2026 - **Apply:** https://startup.jobs/senior-ai-applications-engineer-twin-health-8735799 ## About the Role * Bachelor's degree in Computer Science or a STEM-related field (Master's preferred). * 5+ years of software engineering experience, with a strong foundation in building backend services. * Demonstrated experience in developing and deploying AI-powered applications using Large Language Models (LLMs) like GPT, Claude, or Gemini. * Strong practical knowledge of prompt engineering, vector databases, Retrieval-Augmented Generation (RAG), and other techniques for building reliable LLM-based systems. * Proficiency in Java and/or Python and experience developing microservices. * Hands-on experience with SQL databases (PostgreSQL, MySQL) and query optimization. * Proven ability to work across disciplines, collaborating effectively with product, design, and non-technical stakeholders to build user-centric solutions. * Excellent communication skills and a demonstrated ability to navigate ambiguity and drive projects from concept to completion. * Experience in healthcare, biosensors, or related fields is a plus but not required. * This remote opportunity based out of the U.S. Applicants must be authorized to work for any employer in the U.S. ## Description * Lead the design, development, and deployment of sophisticated AI agents and tools that streamline clinical decision-making, automate complex administrative tasks, and enhance clinical workflows. * Explore and implement the full-stack architecture required for AI-agentic systems, from context engineering, MCP servers, to API design and deployment. * Architect and build robust, scalable backend services and integrations (using Python, Java Spring Boot, SQL) that serve as the foundation for our AI applications. * Collaborate with cross-functional teams to shape the user experience of AI systems, translating clinical and operational needs into concrete technical specifications and prototypes. * Champion best practices for developing reliable, secure, and scalable AI applications, ensuring all solutions meet compliance standards such as HIPAA. * Mentor and coach other engineers, modeling cross-functional thinking and helping to elevate the team's capabilities in building AI-driven products. * Monitor and optimize the performance of AI systems in production to handle rapid growth and ensure a seamless user experience. * Take on additional responsibilities as needed, including on-call rotations. * Regular travel to our Menlo Park headquarters for planning workshops and team collaboration sessions. * Other duties as assigned. ## Related Videos - [Coffee with Developers - Maria Apazoglou](https://www.wearedevelopers.com/videos/1209-coffee-with-developers-maria-apazoglou) - [ Evaluating AI models for code comprehension](https://www.wearedevelopers.com/videos/1462-evaluating-ai-models-for-code-comprehension) - [MySQL Protocol Features You Should Be Aware Of](https://www.wearedevelopers.com/videos/100267-mysql-protocol-features-you-should-be-aware-of) - [Developing the Backend with Stefan Lingler, CTO at Shpock](https://www.wearedevelopers.com/videos/100360-developing-the-backend-with-stefan-lingler-cto-at-shpock) - [Streaming AI Responses in Real-Time with SSE in Next.js & NestJS](https://www.wearedevelopers.com/videos/1630-streaming-ai-responses-in-real-time-with-sse-in-next-js-nestjs) - [Coding for Good: Achieving social change with an app](https://www.wearedevelopers.com/videos/1645-coding-for-good-achieving-social-change-with-an-app) ## Related Articles - [How to Become an AI Engineer](https://www.wearedevelopers.com/magazine/331-how-to-become-an-ai-engineer) - [What Are Large Language Models?](https://www.wearedevelopers.com/magazine/304-what-are-large-language-models) - [MLOps And AI Driven Development](https://www.wearedevelopers.com/magazine/82-mlops-and-ai-driven-development) - [Fully Remote Software Engineer Jobs](https://www.wearedevelopers.com/magazine/447-fully-remote-software-engineer-jobs) - [Navigating the AI Shift](https://www.wearedevelopers.com/magazine/629-navigating-the-ai-shift) - [Got AI ideas but no money? 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