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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Platform Engineer - **Company:** ORCHESTRA BIO, INC. - **Location:** San Francisco, CA, United States - **Experience:** Expert - **Contract:** Permanent contract - **Skills:** Artificial Intelligence, Amazon Web Services, Microsoft Azure, Big Data, Cloud Computing, Continuous Integration, Data Security, Database Applications, Monitoring of Systems, Operational Data Store, Performance Tuning, Unstructured Data, Cloudformation, Infrastructure Automation Frameworks, Build Tools, Terraform - **Published:** September 4, 2026 - **Apply:** https://startup.jobs/senior-platform-engineer-orchestra-bio-8117947 ## About the Role * 5+ years of platform/infrastructure engineering or SRE experience * Strong expertise in cloud infrastructure (AWS/GCP/Azure) including IaC tools (Terraform, CloudFormation) * Hands-on experience with monitoring and observability, implementing and running alerting systems and incident response * Hands-on experience with CI/CD pipeline design, implementation and maintenance * Collaborative mindset with proven track record of working effectively in small, fast-moving engineering teams Preferred * SOC 2 compliance implementation experience: security controls, monitoring, audit preparation * Performance optimization experience for data intensive applications * AI-assisted development proficiency; leveraging tools to accelerate infrastructure work ## Description We're seeking a Senior Platform Engineer to join our growing team in San Francisco. You'll build and maintain the foundational infrastructure that powers Orchestra's intelligent R&D management platform, ensuring our systems can scale reliably as we help more companies bring breakthrough innovations to market. Challenges You'll Tackle Mission Critical Infrastructure: Design and maintain the cloud infrastructure that biotech companies depend on for managing billion dollar R&D programs. Build systems that handle sensitive scientific data, complex financial modeling, and AI workloads with the reliability and security these high stakes operations demand. Scalable AI Operations: Create the platform infrastructure that powers our AI driven signals extraction from meeting transcripts, documents, and operational data. Design systems that can process unstructured data at scale while maintaining performance and cost efficiency as our customer base grows. Developer Experience: Create tooling and infrastructure that enables our engineering team to ship features rapidly and reliably. Design CI/CD pipelines, monitoring systems, and development environments that help us maintain quality while moving at startup speed. Security & Compliance: Implement infrastructure that meets the stringent requirements of biotech and pharmaceutical companies. Build towards SOC 2 compliance while maintaining the development velocity needed in a fast-growing startup environment. What Sets You Apart Complexity: You understand how to build platform infrastructure for complex, data-intensive applications where reliability directly impacts scientific outcomes. You're excited about the technical challenges of supporting AI workloads, financial modeling, and secure data processing at scale. Curiosity: You're genuinely curious about how breakthrough products are developed and excited about building infrastructure that helps scientific organizations operate more effectively. You want your platform work to contribute to bringing medicines and other innovations to market. Agency: You're drawn to environments where you can shape both the technical infrastructure and operational practices. You enjoy the responsibility of building foundational systems that will scale, balancing the speed needed at an early stage company with the reliability required for mission critical software. ## Related Videos - [Alibaba Big Data and Machine Learning Technology](https://www.wearedevelopers.com/videos/37-alibaba-big-data-and-machine-learning-technology) - [Infrastructure as Code: The Developer's Secret Weapon](https://www.wearedevelopers.com/videos/1221-infrastructure-as-code-the-developer-s-secret-weapon) - [Modern Data Architectures need Software Engineering](https://www.wearedevelopers.com/videos/1030-modern-data-architectures-need-software-engineering) - [From Pipelines to Platforms: How DevOps Automation Becomes a Force Multiplier at Scale](https://www.wearedevelopers.com/videos/1946-from-pipelines-to-platforms-how-devops-automation-becomes-a-force-multiplier-at-scale) - [PySpark - Combining Machine Learning & Big Data](https://www.wearedevelopers.com/videos/44-pyspark-combining-machine-learning-big-data) - [Platform Engineering vs. DevOps Why not both?](https://www.wearedevelopers.com/videos/885-platform-engineering-vs-devops-why-not-both) ## Related Articles - [How We Built a Worry-Free System That Runs for 10+ Years – And What We’d Do Again](https://www.wearedevelopers.com/magazine/751-how-we-built-a-worry-free-system-that-runs-for-10-years-and-what-we-d-do-again) - [Highest Paying Tech Companies for Developers](https://www.wearedevelopers.com/magazine/220-highest-paying-tech-companies-for-developers) - [The Best X (Twitter) Accounts for Developers](https://www.wearedevelopers.com/magazine/294-the-best-x-twitter-accounts-for-developers) - [What Are The Top Skills Required For Azure Developers?](https://www.wearedevelopers.com/magazine/77-what-are-the-top-skills-required-for-azure-developers) - [DevOps Engineer Salary [2023]](https://www.wearedevelopers.com/magazine/203-devops-engineer-salary-2023) - [Navigating the AI Shift](https://www.wearedevelopers.com/magazine/629-navigating-the-ai-shift)