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# Smt Technician

- **Company:** CareerCircle
- **Location:** San Francisco, CA, United States
- **Experience:** Expert
- **Salary:** $142,400.0 - $224,100.0
- **Contract:** Permanent contract
- **Skills:** Microsoft Excel, Artificial Intelligence, Business Analytics Applications, Data Analysis, Microsoft Outlook, SAP (Applications), Statistical Process Control (SPC)
- **Published:** September 13, 2026
- **Apply:** https://www.careercircle.com/jobs/all/all/usa/ca/san-diego/fe3dc502-46c6-43f8-9c96-a45967b475a4

## About the Role

* Bachelor's (with 13+ years), Master's (with 9+ years) or Ph.D. (with 5+ years) in immunology, cell biology, molecular biology, translational science, biomedical sciences or related discipline and relevant experience., * Strong foundation in immunology, inflammation, autoimmunity, or related immune-mediated disease biology.
 * Demonstrated ability to independently design, troubleshoot, and interpret complex biological experiments.
 * Hands-on experience with primary cell culture, immune-cell assays, co-culture systems, tissue models, or ex vivo human sample platforms.
 * Ability to analyze biological, biochemical, immunological, and translational assay data and design follow-up studies.
 * Clear communication of complex science to multidisciplinary audiences.
 * Effective collaboration across functions and ability to contribute to multiple projects in a matrixed environment.

Preferred Experience and Skills:

 * Experience developing translational models of inflammatory or autoimmune disease, immune-cell activation, tissue inflammation, or immune-mediated pathology.
 * Expertise with flow cytometry, cytokine profiling, imaging, multiplex tissue analysis, spatial biology, transcriptomics, or related platforms.
 * Experience integrating human datasets with experimental models to define mechanism of action, pharmacodynamic biomarkers, responder hypotheses, or combination strategies.
 * Experience supporting drug discovery from target validation through candidate nomination or early clinical translation.
 * Familiarity with immune-mediated diseases such as IBD, rheumatoid arthritis, hidradenitis suppurativa, psoriatic disease, lupus, asthma, or atopic dermatitis.
 * Experience leading external collaborations or coordinating CRO work.

#EligibleforERP, Autoimmune Diseases, Cell Biology, Cell Cultures, Immunology, Immunology Research, Immunotherapy, Inflammatory Diseases, Molecular Cell Biology, Translational Research, San Diego, CA*On-Site

Visionary
Leadership
Innovation
Electronics
Prototyping
Cleanliness
Calibration
Communication
Data Analysis
Investigation
Test Equipment
Failure Causes
Detail Oriented
Microsoft Excel
Problem Solving
SAP Applications
Microsoft Outlook
Technical Support
Lean Manufacturing
Process Improvement
Experimental Design
Technical Assistance
Six Sigma Methodology
Electronic Components
Printed Circuit Board
Manufacturing Processes
Artificial Intelligence
Manufacturing Engineering
Electronics Manufacturing
Engineering Design Process
Statistical Process Controls
Continuous Improvement Process
Troubleshooting (Problem Solving)
Failure Mode And Effects Analysis
International Traffic In Arms Regulations, Leadership
Data Entry
Hand Tools
Electronics
Cleanliness
Test Equipment
Detail Oriented
Quality Control
Health Advocacy
Lean Manufacturing
Business Solutions
Product Flow Diagram
Printed Circuit Board

## Description

Biology, Research
Innovation
Biomarkers
Immunology
Compassion
Coordinating
Biochemistry
Data Science
Cell Biology
Pharmacology
Communication
Cell Cultures
Immunotherapy
Prioritization
Drug Discovery
Flow Cytometry
Pathophysiology
Pharmacodynamics
Telephone Skills
Disease Modeling
Assay Development
Molecular Biology
Biochemical Assays
Biomedical Sciences
Data Interpretation
Contingent Workforce
Rheumatoid Arthritis
Translational Medicine
Pre-Clinical Development
Troubleshooting (Problem Solving), The Associate Principal Scientist will lead translational discovery activities through strong expertise in immune cell biology, human disease models, assay development, and data interpretation. The candidate will use primary immune cell systems, ex vivo patient samples, co-culture models, tissue analyses, and multi-omics datasets to build decision-enabling translational packages., * Design, execute, analyze, and interpret translational experiments to validate therapeutic targets in immunology, inflammation, and autoimmunity.

 * Develop disease-relevant in vitro, ex vivo, co-culture, and patient-derived tissue models.
 * Integrate mechanistic, pharmacology, transcriptomic, spatial, and biomarker data to connect target biology with disease pathophysiology and mechanism of action.
 * Generate decision-enabling data packages to support target prioritization, candidate progression, biomarker hypotheses, and patient selection.
 * Apply deep immunology expertise to design fit-for-purpose experiments and address key scientific questions.
 * Introduce innovative translational models, technologies, and analytical platforms.
 * Represent the function on project teams and communicate plans, progress, risks, and recommendations clearly.
 * Collaborate with discovery biology, translational medicine, biomarker sciences, data science, pharmacology, clinical development, academia, and CRO partners.
 * Mentor junior scientists through scientific guidance, experimental oversight, and data interpretation support.
 * Promote scientific rigor, high-quality documentation, inclusion, and a one-team mindset.


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