> Markdown version of [/jobs/ext/2994620-senior-principal-scientist-data-science-rwe](https://www.wearedevelopers.com/jobs/ext/2994620-senior-principal-scientist-data-science-rwe). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Senior Principal Scientist, Data Science RWE - **Company:** Johnson & Johnson - **Location:** Hopewell Township, NJ, United States - **Experience:** Expert - **Salary:** $137,000.0 - $235,750.0 - **Contract:** Permanent contract - **Skills:** Computer Programming, Databases, Data Mining, Python (Programming Language), SAS (Software) - **Published:** September 19, 2026 - **Apply:** https://www.techcareers.com/job.asp?id=3397033157&tx=FR9794FFR&pt=1&aff=0B19D771-A501-4A5E-8338-2A822B784D54&utm_source=Job%20Feed&utm_medium=textkernel&utm_campaign=DE&utm_term=0B19D771-A501-4A5E-8338-2A822B784D54 ## About the Role * A Ph.D. degree in epidemiology or biostatistics * Expert coding skills using R, Python, or SAS * At least 5 years of relevant experience within biopharma companies, RWE consulting firms, or other relevant healthcare industries * Extensive hands-on experience with data extraction, cleaning, and analysis, as well as statistical methods to mitigate confounding and selection biases * Expertise with multiple real-world data sources (EHR, insurance claims, registry data). Familiarity with clinical trial data structure * Excellent interpersonal, communication and presentation skills, * Familiarity with drug discovery and the clinical development process * Subject matter knowledge in oncology, Immunology or Neuroscience * Experience in regulatory-grade evidence, communicating and responding to agency reviews and comments. ## Description * Provide thought leadership and hands-on programming expertise for developing and applying Real-World Data ("RWD") methodologies to mitigate observed and unobserved biases in the execution of external control arm studies, hybrid control studies, comparative effectiveness analyses, etc. * Provide thought leadership and hands-on programming expertise to generate actionable insights from post-hoc RCT analyses, observational databases, and literature reviews to support regulatory agency interactions. * Independently create study protocols, statistical analysis plans, and statistical programming deliverables including analysis-ready data, tables and figures * Partner with the Data Science Therapeutic Area scientists to conceptualize, lead, shape and deliver Real World Evidence ## Related Videos - [Data Science on Software Data](https://www.wearedevelopers.com/videos/162-data-science-on-software-data) - [Geometric deep learning for drug discovery](https://www.wearedevelopers.com/videos/264-geometric-deep-learning-for-drug-discovery) - [Times of (climate) crisis - How and why sustainable software is a must!](https://www.wearedevelopers.com/videos/988-times-of-climate-crisis-how-and-why-sustainable-software-is-a-must) - [Kubernetes and Microservices with Multi-Model Databases](https://www.wearedevelopers.com/videos/382-kubernetes-and-microservices-with-multi-model-databases) - [May I interest you in ... R?](https://www.wearedevelopers.com/videos/445-may-i-interest-you-in-r) - [Beyond Gut Feelings: The Rise of Data-Driven HR](https://www.wearedevelopers.com/videos/1326-beyond-gut-feelings-the-rise-of-data-driven-hr) ## Related Articles - [Résumé-Driven Development: How IT trends affect the job market for software developers](https://www.wearedevelopers.com/magazine/59-resume-driven-development-how-it-trends-affect-the-job-market-for-software-developers) - [How We Built a Worry-Free System That Runs for 10+ Years – And What We’d Do Again](https://www.wearedevelopers.com/magazine/751-how-we-built-a-worry-free-system-that-runs-for-10-years-and-what-we-d-do-again) - [Coffee with Developers - Maria Apazoglou - Making AI understandable for all in production](https://www.wearedevelopers.com/magazine/475-coffee-with-developers-maria-apazoglou-making-ai-understandable-for-all-in-production) - [Data Analyst Salary in the UK](https://www.wearedevelopers.com/magazine/278-data-analyst-salary-in-the-uk) - [What’s the Difference between a Junior, Mid, and Senior Developer?](https://www.wearedevelopers.com/magazine/238-what-s-the-difference-between-a-junior-mid-and-senior-developer) - [Data Analyst Salary in Switzerland](https://www.wearedevelopers.com/magazine/276-data-analyst-salary-in-switzerland)