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# Senior Scientist- Translational PKPD

- **Company:** Genentech
- **Location:** South San Francisco, CA, United States
- **Experience:** Expert
- **Salary:** $120,700.0 - $224,100.0
- **Contract:** Permanent contract
- **Skills:** MATLAB, WinNonlin Software
- **Published:** September 19, 2026
- **Apply:** https://dejobs.org/x/x/39845A3A15CA4974939866A5ECEEA859/job/

## About the Role

* Ph.D., or M.D., or PharmD degree or equivalent curriculum in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology or related disciplines is required (experience is specific to job level). Persons without formal degree who have comparable depth and breadth of training and experience (gained at GNE or elsewhere), and who meet job-specific criteria, are eligible for consideration; 0-2 years of industry or postdoctoral experience in PKPD of biologics and drug development.
 * Outstanding record of accomplishment in his/her field as evidenced by his/her co authored publications, patents, internal reports and/or regulatory filings. .
 * Strong knowledge of laboratory techniques and safety is required; Regular GLP and laboratory safety training is required
 * Experience in quantitative PKPD software (e.g., WinNonlin, NONMEM, ADAPT II, Matlab, Simbiology, R)
 * Demonstrated independent thought and creativity in relevant discipline; independently designs, carries out, analyzes, interprets, and documents studies and experiments;
 * Good communication skills, independently presents at department and project team meeting

## Description

We advance science so that we all have more time with the people we love.

This opening is for a Senior Scientist position in the translational Pharmacokinetics and Pharmacodynamics (tPKPD) department within the Development Sciences division in Genentech Research and Early Development (gRED) unit.

The focus of this position is to support the preclinical pharmacokinetic and pharmacodynamics (PKPD) efforts to guide the design, delivery and development of biologics in the Genentech pipeline. Core responsibilities include providing technical support for the PKPD assessment of drug candidates and marketed products and working independently or under the direct supervision of a Scientist.

The Opportunity:

The responsibilities of this Senior Scientist position will :

 * Design, conduct, analyze and interpret all in vitro and in vivo ADME and PKPD studies that are necessary to understand the pharmacology of drug candidates in animals and predict their behavior in humans
 * Prepare summary tables and reports for non-clinical studies; may prepare documents for regulatory agencies, including INDs and BLAs under the supervision of a Scientist
 * Present data at project teams and department meetings and conferences as appropriate
 * Publish innovative PKPD focused research in high quality scientific, technical or medical journals.
 * Manage an active laboratory program that supports basic research in PKPD and also supports pipeline projects
 * Collaborate with other departments such as Clinical Pharmacology, Research, Bioanalytical Sciences, Safety Assessment, PD Biomarker/OMNI, Antibody Engineering, Non-clinical Biostatistics, Regulatory Affairs, Technical Development, and others
 * Participate in compliance and safety related activities. Perform other duties, as assigned


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