> Markdown version of [/jobs/ext/3027879-senior-it-applications-administrator](https://www.wearedevelopers.com/jobs/ext/3027879-senior-it-applications-administrator). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Senior IT Applications Administrator - **Company:** Life Technologies - **Location:** Florence, KY, United States - **Experience:** Expert - **Contract:** Permanent contract - **Skills:** Software Applications, Configuration Management, Data Integrity, Middleware, Laboratory Information Management Systems, Serial Communications, Software Deployment, System Testing, Systems Integration, TCP/IP, Iq/oq/pq, Test Scripts, Information Technology, Health Level Seven International, GXP - **Published:** September 22, 2026 - **Apply:** https://www.jobmonkeyjobs.com/career/28039566/Senior-It-Applications-Administrator-Ohio-Cincinnati-7377 ## About the Role *Must be able to pass a comprehensive background check, which includes a drug screening(where applicable), * Bachelor's degree in IT, Computer Science, Engineering, Clinical Laboratory Science, Medical Technology, or a related field; equivalent experience may be considered. * 5+ years of experience supporting regulated laboratory, healthcare, clinical, or manufacturing applications. * 3+ years of experience with laboratory instruments, middleware, LIS, or medical device integrations. * Experience with GxP environments, CSV, IQ/OQ/PQ, change control, validation documentation, and audit support. * Knowledge of TCP/IP, serial communications, interface troubleshooting, and configuration management., * Experience with Instrument Manager or comparable laboratory middleware. * Knowledge of HL7, ASTM, GAMP 5, laboratory workflows, and quality control systems. * Experience with audit trails, data integrity assessments, assay validation, and reportable ranges. * Experience in clinical laboratories, pharmaceutical, biotechnology, CRO, or medical device environments. Regulatory Knowledge: 21 CFR Part 11 * GxP * GCP * GLP * GDP * CSV * ALCOA+ * Change Control * CAPA * Deviation Management, * Frequently stationary for 6-8 hours per day. * Repetitive hand movement of both hands. * Frequent mobility required. * Occasional crouching, stooping, bending and twisting. * Light to moderate lifting and carrying up to 15-20 lbs. * Ability to use a variety of computer software. * Ability to communicate information and ideas effectively, with the ability to listen to, and understand, information and ideas presented through spoken words and sentences. * Frequently interacts with others to obtain or relate information to diverse groups. * Ability to multitask and perform under stress. * Regular and consistent attendance. ## Description The Senior Application Administrator is responsible for administering, configuring, validating, and supporting laboratory middleware, LIS applications, and instrument interfaces within a regulated GxP environment. This role ensures reliable instrument-to-LIS integrations, data integrity, regulatory compliance, and appropriate system lifecycle documentation. The position works closely with Laboratory Operations, Quality Assurance, Validation, and IT teams., * Administer and support laboratory middleware, LIS applications, and instrument interfaces. * Configure instrument connections, test/code mappings, routing rules, communication parameters, and application settings. * Support onboarding and implementation of new instruments, analyzers, assays, and laboratory interfaces. * Manage configurations across Development, Test, Validation, and Production environments. * Troubleshoot interface, connectivity, mapping, transmission, and data integrity issues. * Execute Computer System Validation (CSV) activities, including IQ, OQ, and PQ. * Develop and execute validation protocols, test scripts, traceability documentation, and validation evidence. * Perform end-to-end testing from instrument processing through middleware and LIS reporting. * Review logs, audit trails, interface transactions, and reports to verify data integrity. * Support change controls, risk assessments, system upgrades, configuration changes, and production deployments. * Maintain compliance with 21 CFR Part 11, GxP, GDP, ALCOA+, and company quality procedures. * Maintain audit-ready documentation and support internal and regulatory inspections. * Collaborate with Laboratory Operations, QA, Validation, and IT teams and provide technical guidance to junior administrators. ## Related Videos - [More efficient software for more efficient microchips](https://www.wearedevelopers.com/videos/1164-more-efficient-software-for-more-efficient-microchips) - [An Applied Introduction to eBPF with Go](https://www.wearedevelopers.com/videos/1075-an-applied-introduction-to-ebpf-with-go) - [Blueprints for Success: Steering a Global Data & AI Architecture](https://www.wearedevelopers.com/videos/1577-blueprints-for-success-steering-a-global-data-ai-architecture) - [SMART Test Automation - the experience of legacy transformation](https://www.wearedevelopers.com/videos/100215-smart-test-automation-the-experience-of-legacy-transformation) - [Turning Container security up to 11 with Capabilities](https://www.wearedevelopers.com/videos/718-turning-container-security-up-to-11-with-capabilities) - [Debunking the Top 10 Myths about Web 3](https://www.wearedevelopers.com/videos/634-debunking-the-top-10-myths-about-web-3) ## Related Articles - [The Most Popular IT Jobs on the Market](https://www.wearedevelopers.com/magazine/376-the-most-popular-it-jobs-on-the-market) - [How We Built a Worry-Free System That Runs for 10+ Years – And What We’d Do Again](https://www.wearedevelopers.com/magazine/751-how-we-built-a-worry-free-system-that-runs-for-10-years-and-what-we-d-do-again) - [System change: restart as developer?](https://www.wearedevelopers.com/magazine/39-system-change-restart-as-developer) - [IT Salaries in UK](https://www.wearedevelopers.com/magazine/288-it-salaries-in-uk) - [Top-Paying Tech Jobs (with Salaries)](https://www.wearedevelopers.com/magazine/372-top-paying-tech-jobs-with-salaries) - [The 8 Best Code Testing Tools](https://www.wearedevelopers.com/magazine/402-the-8-best-code-testing-tools)