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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Senior Backend Engineer (Python / FastAPI) - **Company:** Roche - **Location:** Barcelona, Spain - **Contract:** Permanent contract - **Skills:** Application Programming Interfaces (APIs), Artificial Intelligence, Amazon Web Services, Amazon S3, Automation of Tests, Bioinformatics, Cloud Computing, Cloud Computing Security, Software Quality, Collaborative Software, Data Structures, Relational Databases, EHealth, Python (Programming Language), PostgreSQL, Machine Learning, NumPy, Query Optimization, Software Engineering, SQLAlchemy, Cloud Platform System, Infrastructure as Code (IaC), Backend, Fastapi, Pytest, AWS Fargate, Machine Learning Operations, Front End Software Development, Api Design, Restful APIs, Meditech, Data Pipelines, Api Management - **Published:** June 4, 2026 - **Apply:** https://opcionempleo.com/jobad/es973fc67a0e91b886fa167883a10629ae ## About the Role You are a proactive, collaborative software engineer who thrives on solving complex backend challenges. You possess a strong analytical mindset, are passionate about clean API boundaries, and excel at transforming data infrastructure to drive meaningful progress., The Must-Haves: 5+ years of software engineering experience, with Python as your primary language. Strong software engineering fundamentals, including robust API design and experience building and scaling RESTful systems. Solid understanding of relational databases, data modeling, schema migrations, and query optimization. Proven experience building, deploying, and managing scalable infrastructure in cloud environments, ideally utilizing Infrastructure as Code (IaC). A strong focus on code quality, automated testing, and maintainability within CI/CD pipelines. Demonstrated ability to make progress in ambiguous environments, taking ownership of problems end-to-end-from understanding user needs to shipping production-ready solutions. Tech Stack Alignment: Hands-on experience with, or a strong foundation to quickly adapt to, our core stack: FastAPI, PostgreSQL, SQLAlchemy, Alembic, AWS (S3, Aurora, Fargate, Lambda, CDK), pytest, and NumPy. The Nice-to-Haves: Domain knowledge or a strong interest in the life sciences sector, specifically Sequencing, PCR, Bioinformatics, or digital healthcare. Direct experience working with AWS HealthOmics or building data pipelines for genomic/biological data. Background in data-heavy or AI-integrated product architectures, including an interest in how AI/ML systems behave in production. Previous experience working within large, globally distributed enterprise environments (e.g., Pharma, MedTech). At Roche, we embrace emerging innovations, like cloud-native infrastructure and AI, to enhance the patient journey. If you are ready to make a meaningful impact on patients and healthcare systems worldwide through cutting-edge technology, this is the place for you. Let's create a healthier, brighter future for all. * This is an on-site position and no relocation assistance is provided. ## Description We are looking for an experienced Backend Python Engineer to build robust, scalable APIs and services that power our digital products in the life sciences sector. Working closely with our Frontend/UX team and Data Scientists, you will design the backend infrastructure required to process, manage, and serve complex bioinformatics and machine learning data. In this highly collaborative role, you will tackle challenges ranging from optimizing database queries for massive datasets to architecting cloud-native solutions on AWS. We value engineers who are comfortable exploring complex data structures, establishing clean API boundaries, and ensuring high reliability as we scale our platforms to support critical scientific innovation., Design, build, and maintain high-performance, asynchronous backend services and robust RESTful APIs. Architect, deploy, and manage scalable and secure cloud infrastructure, utilizing Infrastructure as Code (IaC) principles. Design efficient database schemas, manage complex data relationships, execute seamless migrations, and ensure performant query optimization for massive datasets. Build and maintain data pipelines to ingest, normalize, and process large volumes of structured and unstructured scientific and bioinformatics data. Champion engineering excellence by writing clean, testable code, implementing comprehensive automated testing, and maintaining reliable CI/CD pipelines. Partner directly with the UX/Frontend team to establish seamless API integrations, and collaborate with Data Scientists to bring machine learning models into production workflows. ## Related Videos - [Intro to FastAPI](https://www.wearedevelopers.com/videos/462-intro-to-fastapi) - [Geometric deep learning for drug discovery](https://www.wearedevelopers.com/videos/264-geometric-deep-learning-for-drug-discovery) - [pytest: Simple, rapid and fun testing with Python](https://www.wearedevelopers.com/videos/213-pytest-simple-rapid-and-fun-testing-with-python) - [Vectorize all the things! Using linear algebra and NumPy to make your Python code lightning fast.](https://www.wearedevelopers.com/videos/562-vectorize-all-the-things-using-linear-algebra-and-numpy-to-make-your-python-code-lightning-fast) - [Shipping Faster with Less: Render on Cloud Hosting, AI Workloads, and the Future of DevOps](https://www.wearedevelopers.com/videos/1894-shipping-faster-with-less-render-on-cloud-hosting-ai-workloads-and-the-future-of-devops) - [Building and Deploying Multi-Agent Systems with ADK and Vertex AI](https://www.wearedevelopers.com/videos/1918-building-and-deploying-multi-agent-systems-with-adk-and-vertex-ai) ## Related Articles - [The 7 Most Popular Backend Frameworks for Developers](https://www.wearedevelopers.com/magazine/403-the-7-most-popular-backend-frameworks-for-developers) - [Fully Remote Software Engineer Jobs](https://www.wearedevelopers.com/magazine/447-fully-remote-software-engineer-jobs) - [Find a Developer Job: 12 Best Job Sites For Developers](https://www.wearedevelopers.com/magazine/165-find-a-developer-job-12-best-job-sites-for-developers) - [The Biggest German Tech Companies](https://www.wearedevelopers.com/magazine/424-the-biggest-german-tech-companies) - [Welcome to Switzerland](https://www.wearedevelopers.com/magazine/4-welcome-to-switzerland) - [Software Developer Salary in Switzerland [2023]](https://www.wearedevelopers.com/magazine/215-software-developer-salary-in-switzerland-2023)