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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # MES Engineer - **Company:** The Lilly Company - **Location:** Houston, TX, United States - **Experience:** Experienced - **Salary:** $66,000.0 - $158,400.0 - **Contract:** Permanent contract - **Skills:** Application Programming Interfaces (APIs), Software Documentation, System Testing, Systems Integration, Iq/oq/pq, Syncade, Low-code, GXP - **Published:** September 10, 2026 - **Apply:** https://www.houstonjobsite.com/job.asp?id=3385148403&tx=KL7777FFQ&pt=1&aff=0B19D771-A501-4A5E-8338-2A822B784D54&utm_source=Job%20Feed&utm_medium=textkernel&utm_campaign=DE&utm_term=0B19D771-A501-4A5E-8338-2A822B784D54 ## About the Role * Pharmaceutical Manufacturing Regulatory compliance knowledge and experience (cGMP) * Experience with DeltaV MES (Previously known as Syncade) Recipe Authoring and validating Master Batch Records (MBRs) in a regulated environment. * Strong analytical and problem-solving skills across applications, configurations, and integrations. * Excellent communication skills, with the ability to articulate complex technical concepts to non-technical audiences. * Ability to work closely with Operations, Quality, Engineering, and IT teams to translate operational needs into executable MES solutions. * Experience with tier-one MES platforms, in particular Emerson Syncade/DeltaV. Your Basic Qualifications * Bachelor's Degree in IT, Engineering, or related technical field, * 5+ years experience with MES system design, implementation, and validation. * 3+ years of experience in regulated pharmaceutical or medical device manufacturing environments. * Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1. Additional Preferences * Prior experience with no-code/low-code frontline platforms, in particular Tulip, and with distributed control systems such as Emerson DeltaV, including recipe and batch interfaces to MES. * Strong documentation skills and attention to detail, with experience in generating validation deliverables and training materials. * Professional experience working in a GxP regulated environment. * Experience commissioning and qualifying systems at a new site, and supporting API, small molecule, oligonucleotide, or synthetic chemistry operations. ## Description The MES Engineer is part of the new API facility's MES team, supporting the design, development, delivery, and computer system validation of DeltaV MES solution. You will implement, configure, and support the MES solution to meet the site's operational, quality, and compliance needs - working closely with Operations, Tech Services, Engineering, Quality, and the broader Tech at Lilly team to ensure successful deployment and long-term support of MES capabilities. Your Primary Responsibilities * Partner with site teams to gather requirements, define digital workflows, and author/validate electronic batch records aligned with operational processes. * Support MES startup activities, including configuration of MES recipes, workflows, electronic work instructions, and electronic batch records (EBRs). * Configuration of electronic logbooks (Equipment Tracking) and Weigh & Dispense * Configuration of MES interfaces with other manufacturing systems (ERP system, Historian, DCS, Manufacturing Equipment via Edge technology, etc) * Implement and support site-level testing and validation efforts (e.g., Installation Qualification, Performance Qualification) to ensure system readiness. * Generation of associated CSV (Computer System Validation) documentation * Troubleshoot MES issues and collaborate with multi-functional teams to resolve system or process gaps. * Support site readiness and go-live efforts, including hypercare support and frontline troubleshooting. * Ensure compliance with Lilly Global Standard Operating Procedures (GSOPs) and Computer System Validation (CSV) standards, including 21 CFR Part 11 and GAMP 5. * Develop and maintain system documentation, SOPs, training materials, and support guides * Collaborate with global/site MES architects and platform teams to align on standards, design, and configuration best practices. ## Related Videos - [Blueprints for Success: Steering a Global Data & AI Architecture](https://www.wearedevelopers.com/videos/1577-blueprints-for-success-steering-a-global-data-ai-architecture) - [Why make use of an integration platform in today's software developments and infrastructure?](https://www.wearedevelopers.com/videos/758-why-make-use-of-an-integration-platform-in-today-s-software-developments-and-infrastructure) - [The Intent Engineer: Closing the Gap Between Business & Engineering - Manuel Klein](https://www.wearedevelopers.com/videos/1855-the-intent-engineer-closing-the-gap-between-business-engineering-manuel-klein) ## Related Articles - [How We Built a Worry-Free System That Runs for 10+ Years – And What We’d Do Again](https://www.wearedevelopers.com/magazine/751-how-we-built-a-worry-free-system-that-runs-for-10-years-and-what-we-d-do-again) - [Is Software Engineering Over-Saturated?](https://www.wearedevelopers.com/magazine/418-is-software-engineering-over-saturated) - [Now is the time for industrialized software development](https://www.wearedevelopers.com/magazine/601-now-is-the-time-for-industrialized-software-development) - [Why Upskilling And Reskilling is Important For Developers](https://www.wearedevelopers.com/magazine/428-why-upskilling-and-reskilling-is-important-for-developers) - [Fully Remote Software Engineer Jobs](https://www.wearedevelopers.com/magazine/447-fully-remote-software-engineer-jobs) - [The Most Popular IT Jobs on the Market](https://www.wearedevelopers.com/magazine/376-the-most-popular-it-jobs-on-the-market)