> Markdown version of [/jobs/ext/3457576-senior-full-stack-engineer](https://www.wearedevelopers.com/jobs/ext/3457576-senior-full-stack-engineer). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Senior Full-Stack Engineer - **Company:** Simulations Plus - **Location:** United States (Remote available) - **Experience:** Expert - **Salary:** $90,000.0 - $110,000.0 - **Contract:** Permanent contract - **Skills:** JavaScript (Programming Language), Application Programming Interfaces (APIs), Artificial Intelligence, Amazon Web Services, Software as a Service, Cloud Computing, Code Review, Cursor, JSON, MongoDB, Node.Js, NoSQL, OAuth, OpenID, Software Engineering, Data Streaming, TypeScript, Tailwind, ReactJS, Large Language Models, Multi-Agent Systems, Backend, Information Technology, Front End Software Development, Restful APIs, GXP - **Published:** September 2, 2026 - **Apply:** https://www.indeed.com/viewjob?jk=bb4d1ade33ae3b32 ## About the Role * 3+ years of professional software engineering experience, with shipped full-stack work in production * Proficiency in JavaScript or TypeScript across Node.js backend and React frontend * Practical experience with document or NoSQL databases such as MongoDB * Comfort building and consuming REST APIs and JSON contracts * Genuine interest in agents, MCP, and applied AI, and the drive to build real expertise in those areas * Fluency using AI coding tools (Claude, Cursor, Copilot) in daily workflow, * Familiarity with Anthropic, OpenAI, or other LLM provider SDKs * Exposure to MCP, agent frameworks, or LLM-integrated product features * Experience with cloud infrastructure (AWS preferred) and CI/CD pipelines * Experience in regulated-software environments (SOC 2, HIPAA, GxP, 21 CFR Part 11) or life-sciences SaaS * Familiarity with Passport, OAuth, OIDC, or comparable auth patterns Education: * Bachelor's degree in computer science, engineering, or related field preferred * Relevant technical certifications welcomed ## Description * Feature Delivery Across the Stack + Own features end-to-end across Node.js and Express backends and React/Tailwind frontends + Build the APIs, UI, and data flows behind real customer-facing functionality + Contribute to the data, auth, and service patterns the platform builds on * AI Feature Integration + Integrate LLM-powered functionality into product surfaces, working alongside the team's AI lead + Wire frontends to LLM and MCP endpoints; handle streaming, errors, and degraded states gracefully + Contribute to evals, fixtures, and tooling that support the AI side of the team * Team Impact + Bring full-stack range to a team that values flexibility across backend, frontend, and AI + Contribute to code reviews, documentation, and the team's shared engineering practices + Apply AI coding tools effectively as part of daily engineering workflow * Other Duties as Assigned