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# Principal Engineer, Algorithm - ECG

- **Company:** Danaher Corporation
- **Location:** Irvine, CA, United States
- **Salary:** $170,000.0 - $215,000.0
- **Contract:** Permanent contract
- **Skills:** Algorithm Design, C++ (Programming Language), Cloud Computing, Computer Programming, Computer Engineering, Python (Programming Language), MATLAB, Machine Learning, Signal Processing, Feature Extraction
- **Published:** October 2, 2026
- **Apply:** https://dejobs.org/x/x/B274D04450D54844986BA1676D1839F4/job/

## About the Role

* B.S. Degree in Electrical Engineering, Biomedical Engineering, Computer Engineering, or a related field.
 * 12+ years of relevant experience in ECG algorithm development, signal processing, or related domain.
 * Deep expertise in ECG signal processing, digital signal processing, and statistical modeling.
 * Proven experience developing ECG algorithms, including waveform detection and cardiac feature extraction.
 * Strong programming skills in C/C++, MATLAB, Python, or similar.
 * Experience working with large-scale physiological or clinical datasets.
It would be a plus if you also possess previous experience in:

 * Master's or Ph.D. in Electrical Engineering, Biomedical Engineering, Computer Engineering, or a related field.
 * Experience with arrhythmia detection/classification algorithms or cardiac monitoring systems.
 * Knowledge of cardiac physiology and electrophysiology principles.
 * Experience applying machine learning techniques to ECG or time-series physiological data.
 * Familiarity with wearable or ambulatory ECG systems and associated signal challenges.

## Description

The Principal Engineer, Algorithm - ECG is responsible for the architecture, development, and advancement of ECG signal processing algorithms that support accurate and reliable cardiac monitoring across Masimo's non-invasive platforms. This role provides technical and project leadership for the innovation in ECG-based measurements, including heart rate, rhythm analysis, and advanced cardiac insights, translating complex physiological signals into clinically meaningful outputs.

This role collaborates closely with cross-functional teams spanning hardware, software, systems, and clinical disciplines to develop high-performance, regulatory-compliant solutions from concept through commercialization.

The position reports to the Manager, Algorithm - ECG and is part of the R&D Algorithm Engineering department located in Irvine, CA and will be an on-site role.

In This Role, You Will Have The Opportunity To:

 * Lead the design and development of advanced ECG signal processing algorithms, including filtering, feature extraction, waveform delineation, and rhythm classification.
 * Architect scalable algorithm frameworks for ECG analysis, supporting real-time embedded implementation and cloud-based analytics where applicable.
 * Develop and optimize algorithms for heart rate detection, arrhythmia identification, and ECG morphology analysis.
 * Design and conduct validation strategies using clinical datasets to ensure algorithm accuracy, robustness, and generalizability across diverse patient populations.
 * Translate clinical and regulatory requirements into algorithm design inputs, ensuring compliance with applicable standards (e.g., FDA, IEC).