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# Statistical Programmer II (PK)

- **Company:** ICON plc
- **Location:** Reading, UK
- **Experience:** Expert
- **Contract:** Permanent contract
- **Skills:** Clinical Data Repository, Data Cleansing, R (Programming Language), Information Technology, Data Management
- **Published:** October 10, 2026
- **Apply:** https://dejobs.org/x/x/7FE7521D878846798E9AB4CAB075BCEB/job/

## About the Role

We are seeking an experienced Pharmacometrics Support Programmer to join a global FSP team. This is an opportunity for a highly analytical programmer with strong R programming expertise and experience in PK/PD data preparation to contribute to critical drug development programmes., * Bachelor's degree in a Life Science, Health Science, Statistics, Computer Science, IT, or related discipline.

 * Minimum of 6 years' experience within the pharmaceutical, biotechnology, or CRO industry.
 * Strong programming expertise in R.
 * Experience developing and quality controlling NONMEM PK/PD datasets.
 * Working knowledge of PK/PD principles and pharmacometric workflows.
 * Strong understanding of SDTM, ADaM, and CDISC standards, including controlled terminology.
 * Experience supporting NONMEM file creation, quality control, submissions, and standardisation activities.
 * Strong attention to detail and commitment to data quality.
 * Excellent written and verbal communication skills in English.

Desired Skills

 * Experience reviewing and managing outsourced programming deliverables.
 * Experience validating or quality controlling customised R packages.
 * Demonstrated ability to identify process improvements and drive standardisation initiatives.
 * Ability to work effectively across global, cross-functional teams.

## Description

In this role, you will be responsible for the creation, quality control, and standardisation of NONMEM PK/PD datasets, supporting pharmacometric modelling activities across a diverse clinical portfolio. Working closely with Data Management, Statistical Programming, Statistics, Bioanalytical teams, and external partners, you will play a key role in ensuring high-quality pharmacometric data is delivered on time and to the highest regulatory standards., * Develop and quality control NONMEM PK/PD datasets using SDTM and ADaM data sources.

 * Support pharmacometric modelling activities by delivering accurate, complete, and submission-ready datasets.
 * Perform quality review of internally and externally produced NONMEM datasets.
 * Collaborate with Data Management, Statistical Programming, Statistics, Clinical Pharmacology, and Bioanalytical teams to resolve data issues and ensure project timelines are met.
 * Contribute to the preparation of regulatory submission projects in accordance with internal pharmacometrics guidelines.
 * Conduct quality control testing of customised R packages used to standardise pharmacometric workflows.
 * Develop and maintain testing frameworks and validation processes for departmental R tools and packages.
 * Identify data discrepancies, process improvements, and opportunities for greater automation and efficiency.
 * Actively contribute to the development and implementation of new pharmacometric standardisation initiatives.
 * Ensure all deliverables comply with applicable SOPs, working instructions, regulatory requirements, and ICH-GCP guidelines.
 * Maintain inspection readiness through ongoing training and adherence to quality standards., * Opportunity to work within a globally recognised Clinical Pharmacology & Pharmacometrics function.
 * Contribute directly to innovative drug development programmes.
 * Work in a highly collaborative and scientifically driven environment.
 * Be part of ongoing innovation and standardisation initiatives within pharmacometrics and clinical data science.
 * Use your expertise to influence best practices and improve the efficiency and quality of pharmacometric deliverables.

If you are passionate about leveraging R programming, pharmacometrics, and data quality excellence to support drug development, we'd love to hear from you.