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# Staff Systems Support Engineer

- **Company:** Illumina, Inc
- **Location:** Great Abington, UK
- **Salary:** £69,500.0 - £104,300.0
- **Contract:** Permanent contract
- **Skills:** Data Analysis, Confluence, JIRA, Bioinformatics, Computer Programming, Linux, Firmware, Laboratory Information Management Systems, Software Engineering, Software Systems, Systems Integration, Jama (Software), Information Technology
- **Published:** October 11, 2026
- **Apply:** https://www.adzuna.co.uk/jobs/details/5923017774

## About the Role

* Bachelor's or Master's degree in Computer Science, Engineering, Bioinformatics, Physical Sciences, or a related discipline.
 * Significant experience supporting complex opto-electronic systems in a commercial or R&D environment.
 * Strong troubleshooting capability across integrated hardware, firmware, and software systems.
 * Coding experience and hands-on experience working with Linux operating systems.
 * Experience troubleshooting and diagnosing PCB-level issues.
 * Strong communication skills with the ability to convey technical concepts to both technical and non-technical audiences.
 * Ability to thrive in a dynamic, fast-paced environment and manage competing priorities.

Preferred Experience

 * Experience working with sequencing instrumentation or related life science technologies.
 * Knowledge of enterprise processes and tools such as Jira, Jama, and Confluence.
 * Experience working within cross-functional and geographically distributed teams.

## Description

As a Staff Systems Support Engineer, you will join our Global Lab Management team and play a critical role in supporting the development of next-generation sequencing technologies. Working at the intersection of hardware, software, engineering, and science, you will help ensure our sequencing instrument fleet operates at the highest standards, empowering R&D teams to deliver the innovations that shape the future of genomics.

At Illumina, you'll work alongside experts across disciplines, contribute to meaningful and innovative projects, and continuously grow through new challenges and experiences. Our culture is built on collaboration, curiosity, and a shared commitment to making an impact.

This is an opportunity to:

 * Support cutting-edge sequencing technologies at the forefront of genomics innovation.
 * Partner with world-class Chemistry, Software, Consumables, Engineering, and Integration teams.
 * Solve complex technical challenges that directly enable scientific breakthroughs.
 * Work in a collaborative, international environment where every contribution matters.
 * Build your expertise while helping advance technologies that improve human health.

As a Staff Systems Support Engineer, you will work closely with Illumina's R&D teams to ensure the sequencing instrument fleet is operational, reliable, and capable of supporting critical development activities. You will leverage your technical expertise across hardware, software, firmware, and systems troubleshooting to maximize instrument performance and enable innovation.

 * Troubleshoot and resolve issues on sequencing instruments to support research and development activities.
 * Collaborate with multidisciplinary teams to ensure instruments are fit for purpose, including implementing hardware and software modifications where required.
 * Monitor instrument performance through sequencing data analysis and execute preventative maintenance and upgrade activities.
 * Partner with EERD and Systems Integration teams to maintain fleet availability and operational excellence.
 * Support, mentor, and provide technical guidance to junior team members.
 * Develop and communicate key performance metrics, including failure analysis and Pareto reporting.
 * Provide timely, clear communication to users regarding investigations, corrective actions, and repair timelines.
 * Collaborate with global instrument and software development teams, including colleagues in the United States, to support software, firmware, and hardware upgrades.
 * Represent the engineering support function on project teams requiring sequencing instrument expertise.