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# DMPK Scientist

- **Company:** Schrodinger, Inc.
- **Location:** New York, NY, United States
- **Experience:** Expert
- **Salary:** $170,000.0 - $290,000.0
- **Contract:** Permanent contract
- **Skills:** Data Integration, MATLAB, Molecular Modeling, WinNonlin Software
- **Published:** October 14, 2026
- **Apply:** https://startup.jobs/dmpk-scientist-schrodinger-10444942

## About the Role

* A DMPK analysis expert, who understands ADME principles and applications throughout drug development applications throughout drug discovery and development
 * A scientist with a robust background in DMPK who has specialized in the use and application of any of the following:

o In vitro/in vivo drug metabolism or transporter approaches to identify potential ADME liabilities and aid in compound optimization

o PK/PD and PBPK modeling approaches to optimize compound selection, dose optimization, and study design (this includes experience with commonly-used PK/PD software, such as Phoenix/WinNonlin, SimCYP, Monolix, MATLAB SimBiology, or other equivalent software)

 * A proven Principal Investigator and scientific strategist who's self-driven and results-oriented
 * A highly motivated, self-driven, and results-oriented data-analyzer
 * An excellent communicator and presenter who can work both as a team player and a project driver
 * A flexible, curious scientist who's excited about networking and building internal and external relationships, * PhD in life sciences, chemical engineering, pharmacokinetics, pharmaceutical sciences, or a related discipline with at least five years of experience working with DMPK in the pharmaceutical industry or Master's degree in life sciences, chemical engineering, pharmacokinetics, pharmaceutical sciences, or a related discipline with at least ten years of experience working with DMPK in the pharmaceutical industry
 * Prior experience independently representing DMPK on project teams, As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us

## Description

* Develop and drive DMPK and PK/PD strategy for drug discovery projects
 * Represent the DMPK group on internal and intercompany project teams to help turn molecular modeling design ideas into druggable novel chemical entities
 * Collaborate with internal and intercompany project team members and external CROs to generate relevant data to enable knowledge and data integration
 * Analyze and integrate in silico ADME predictive solutions, physicochemical, ADME, and DMPK data to impact multiparameter optimization
 * Author and/or review appropriate reports for regulatory submission of development drug candidates and ensure the overall quality of the studies and interpretation (this entails supporting interactions with regulatory agencies)
 * Collaborate with scientific development team on establishment of predictive computational ADME/DMPK models