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# Principal Programmer Analyst

- **Company:** Glaxosmithkline PLC
- **Location:** United States
- **Experience:** Experienced
- **Contract:** Permanent contract
- **Skills:** Clean Code Principles, Agile Methodology, Artificial Intelligence, Computer Programming, Information Engineering, Machine Learning, Information Technology, Programming Languages
- **Published:** October 15, 2026
- **Apply:** https://diversityjobs.com/career/18633147/Principal-Programmer-Analyst-Pennsylvania-Upper-Providence

## About the Role

We are looking for professionals with these required skills to achieve our goals:

 * Bachelor's degree in Mathematics, Computer Science, or a related discipline

 * Five or more years if experience with at least one programming language and ability to evaluate and select appropriate tools or languages for specific tasks
 * Three or more years of experience working in the pharmaceutical/biotech industry with advanced understanding of clinical trials and therapeutic areas, applied to enhance programming outputs and decision-making
 * Experience leading discussions on programming strategies, displays, and custom programs
 * Experience implementing principles of governance, quality control, and compliance with regulatory requirements and programming standards

Preferred Qualifications:

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

 * Experience guiding others in the use of Artificial Intelligence/Machine Learning (AI/ML) tools or applying these tools to improve efficiency
 * Experience contributing to internal technical discussions, forums, or external technical organizations

 * Application of critical thinking to implement standards and collaborate with stakeholders where deviations are required

 * Ability to articulate complex technical information effectively to both technical and non-technical stakeholders
 * Experience contributing to department strategies and key technical initiatives through working groups or sub-teams
 * Demonstrated networking and collaboration across departments, divisions, and external partners
 * Experience facilitating integration across matrix teams and contributing to planning and execution of programming activities
 * Experience guiding teams and individuals, fostering continuous improvement, collaboration, and innovation
 * Demonstrated proficiency in R., Agile Leadership, Agile Methodology, Clinical Development, Data Engineering, Data Science, Influencing Without Authority, Learning Agility, Problem Solving, Statistical Programming

## Description

We are seeking a Principal Programmer Analyst to join our Clinical Programming team, contributing to pipeline delivery across complex and pivotal studies. This role operates within an agile, squad-based environment, where you will lead study delivery, collaborate with cross-functional teams, and act as a technical mentor to ensure high-quality and timely outputs. Working closely with stakeholders across clinical, statistical, and operational functions, you will play a key role in bridging scientific requirements with technical solutions, supporting the successful execution of clinical development programmes within a global setting., * Independently lead programming activities for one or more studies, ensuring development, maintenance, and validation of complex analysis packages

 * Foster quality assurance by ensuring programming activities adhere to standards such as Good Programming Practices and CDISC
 * Mentor junior programmers by providing guidance and support in technical programming tasks and industry best practices
 * Lead programming support for regulatory interactions (e.g., EMA, FDA)
 * Identify gaps and inefficiencies and recommend and implement innovative solutions aligned with standards and best practices
 * Establish and uphold governance frameworks, identify risks early and devise mitigation plans, ensuring timely escalation