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# Principal Data Analyst

- **Company:** University of Pennsylvania
- **Location:** Philadelphia, PA, United States
- **Experience:** Experienced
- **Salary:** $83,500.0 - $104,792.0
- **Contract:** Permanent contract
- **Skills:** Big Data, Databases, Information Engineering, Data Infrastructure, Data Integrity, Machine Learning, Data Strategy, Data Analytics, Data Management, Epic Clarity, Machine Learning Operations
- **Published:** October 16, 2026
- **Apply:** https://dejobs.org/x/x/D695305F82E9424DA81B91690993EBE8/job/

## About the Role

* Bachelor's degree and 4 to 6 years of experience or equivalent combination of education and experience is required.
Job Location - City, State

## Description

This role integrates biostatistics, data science, and data engineering to support and advance the Department of Neurosurgery's research and data infrastructure. The position serves as a core methodological collaborator in neurosurgical research while leading the development and stewardship of a centralized research database built upon Epic Clarity data. This role will play a key part in advancing the department's research strategy through modern data science and robust research infrastructure., Biostatistics and Data Science Collaboration

 * Collaborate with faculty investigators, residents, and fellows on research projects across the full study lifecycle, from study conception through dissemination.
 * Provide consultation on study design, cohort definition, feasibility assessments, and analytic strategy.
 * Serve as statistical lead and analytic strategist across research projects, including development of analysis plans, selection of appropriate methodology, and communication of findings through written reports and presentations.
 * Apply advanced statistical methods, machine learning, and data science techniques to address complex clinical and translational research questions.
 * Identify research opportunities aligned with departmental priorities and translate clinical questions into rigorous research designs.
 * Conduct and oversee data management and statistical analyses supporting departmental research initiatives.
 * Provide methodological leadership and substantive intellectual contribution to manuscript development.
 * Contribute to grant proposals and clinical trial design, including statistical sections, study design consultation, and power/sample size calculations.

Research Data Infrastructure and Engineering

 * Lead the design, evaluation, and evolution of the department's centralized research data infrastructure supporting neurosurgical research, scalable analytics, and machine learning workflows.
 * Assess existing datasets and workflows to identify inconsistencies, redundancies, and opportunities for improved data organization and accessibility.
 * Architect and maintain data pipelines integrating Epic Clarity and other internal or external data sources.
 * Govern data integrity, platform lifecycle, and scientific data stewardship for departmental research data assets.
 * Develop curated analytic datasets and standardized variable definitions to support reproducible research.
 * Enable investigators to access well-structured data resources for research and analytic projects.
 * Collaborate with institutional data partners (e.g. Penn DnA) to align departmental data infrastructure with enterprise data strategy.