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# Principal Software Engineer (.NET / Azure

- **Company:** Centific Technologies, Inc.
- **Location:** United States (Remote available)
- **Experience:** Expert
- **Salary:** $115,000.0 - $194,000.0
- **Contract:** Permanent contract
- **Skills:** ASP.NET, .NET Framework, Application Programming Interfaces (APIs), Agile Methodology, Artificial Intelligence, Application Performance Management, Microsoft Azure, C Sharp (Programming Language), Clinical Data Repository, Cloud Computing, Code Review, Continuous Integration, DevOps, Distributed Systems, Entity Framework, Microsoft SQL Server, SQL Azure, Performance Tuning, Software Engineering, Software Technical Review, Cloud Platform System, ReactJS, Fast Healthcare Interoperability Resources, Retrieval-Augmented Generation, Large Language Models, Electronic Medical Records, Backend, Gitlab, Git, Event Driven Architecture, Information Technology, Atlassian Tools, Health Level Seven International, Bicep, Cosmos DB, Terraform, Serverless Computing, Docker, Key Vault, Web Api, Microservices
- **Published:** October 22, 2026
- **Apply:** https://www.builtincolorado.com/auth/login?destination=/job/principal-software-engineer-net-azure/11158301

## About the Role

* 10+ years of professional software engineering experience

 * Strong proficiency in C# and .NET (including .NET 6+ / ASP.NET Core)

 * Deep experience with Microsoft Azure (App Services, Azure Functions, Service Bus, Azure SQL, Cosmos DB, Storage, Key Vault, Entra ID)

 * Demonstrated ability to operate independently in ambiguous, complex environments with large codebases and distributed systems

 * Strong track record of shipping and maintaining production backend systems at scale

 * Experience in regulated or domain-heavy industries (healthcare, life sciences, finance, or similar)

 * Excellent communication skills with a proven ability to build relationships with non-technical stakeholders and translate between business and engineering contexts

 * Comfort with end-to-end ownership: from requirements gathering through deployment and operational support

Preferred Qualifications

 * Prior experience in Health & Life Sciences technology (EHR/EMR systems, clinical data, regulatory compliance, HIPAA, HL7/FHIR, etc.)

 * Experience with Azure DevOps, CI/CD pipelines, and Infrastructure as Code (Bicep/Terraform)

 * Familiarity with event-driven architectures, microservices patterns, and distributed messaging

 * Experience with data-intensive systems, pipelines, or ML/AI integrations in a healthcare context

 * History of leading cross-team initiatives or serving as a technical anchor on high-impact projects

Tech Stack

 * Languages: C#, .NET 8+

 * Backend: ASP.NET Core Web APIs, Azure Functions, Worker Services

 * Cloud: Microsoft Azure (App Services, AKS/Containers, Service Bus, Event Grid, Azure SQL, Cosmos DB, Blob Storage, Key Vault, Entra ID/MSAL)

 * Data: SQL Server, Cosmos DB, Entity Framework Core

 * DevOps: Azure DevOps, Git, CI/CD pipelines, Docker

## Description

Be an Early Applicant
In-Office or Remote
Hiring Remotely in United States
Expert/Leader
In-Office or Remote
Hiring Remotely in United States
Expert/Leader
Designs and maintains large-scale distributed systems on Azure using C# and .NET. Owns backend services, APIs, data access, cloud infrastructure, CI/CD, and operational support. Drives architecture and technical strategy, resolves systemic production issues, collaborates with business stakeholders, and mentors engineers. The role requires extensive experience with Azure, production backend systems, complex codebases, distributed systems, and regulated or domain-heavy industries, with preferred healthcare and life sciences expertise.
The summary above was generated by AI, * Design, build, and maintain large-scale distributed systems on Azure using .NET/C#

 * Navigate and contribute to complex, legacy and modern codebases with minimal ramp-up time

 * Engage directly with business stakeholders to rapidly build domain expertise and translate requirements into technical solutions

 * Drive architectural decisions, trade-off analyses, and technical strategy for your area

 * Own backend services end-to-end: APIs, data access, cloud infrastructure, CI/CD pipelines

 * Mentor and unblock other engineers; raise the bar on engineering quality and practices

 * Collaborate across organizational boundaries to align technical work with business outcomes

 * Identify and resolve systemic issues in production environments, tooling, and development workflows, Remote
United States
Easy Apply
115K-194K Annually
Mid level
115K-194K Annually
Mid level
Cloud * Security * Software * Cybersecurity * Automation
Designs, operates, and improves production Kubernetes platforms across cloud environments. Manages ArgoCD GitOps workflows, Terraform infrastructure, CI/CD integrations, platform reliability, observability, security controls, and developer enablement. Collaborates with application teams to onboard services, create self-service tooling and documentation, respond to incidents, and improve platform availability and performance.
Top Skills: ArgocdAWSAzureBashCiliumCrossplaneDnsExternal Secrets OperatorGCPGithub ActionsGitlab CiGitopsGoGrafanaHelmIngressIstioKubernetesKyvernoLinkerdLoad BalancingLokiOpa/GatekeeperOpentelemetryPrometheusPythonSealed SecretsService MeshTektonTerraformVault, Atlassian