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# Senior Data Scientist, Biologics Discovery

- **Company:** Johnson & Johnson
- **Location:** Spring House, PA, United States
- **Experience:** Expert
- **Salary:** $109,000.0 - $174,800.0
- **Contract:** Permanent contract
- **Skills:** Artificial Intelligence, Data Analysis, Bioinformatics, Computational Biology, Data Infrastructure, Experimental Data, Monitoring of Systems, Python (Programming Language), Machine Learning, Language Modeling, Molecular Modeling, SQL Databases, Pytorch, Scikit Learn, Information Technology, Machine Learning Operations
- **Published:** October 26, 2026
- **Apply:** https://www.businessworkforce.com/job.asp?id=3467622888&tx=YT1818THD&pt=1&aff=0B19D771-A501-4A5E-8338-2A822B784D54&utm_source=Job%20Feed&utm_medium=textkernel&utm_campaign=DE&utm_term=0B19D771-A501-4A5E-8338-2A822B784D54

## About the Role

* Master's or Ph.D. in Computer Science, Machine Learning, Computational Biology, Bioinformatics, Statistics, or a related field.
 * At least 2 years of applied ML experience, including model development, evaluation, and dataset curation on complex scientific or biomedical data.
 * Strong proficiency with Python and the modern ML stack (e.g., PyTorch, scikit-learn) and SQL.
 * Experience turning complex, heterogeneous experimental data into robust features and training sets, with exposure to cloud training and data infrastructure.
 * Sound understanding of evaluation, validation, and the risks of leakage and distribution shift.
 * Ability to collaborate effectively with experimental scientists and modeling partners in a matrixed R&D environment.

Preferred

 * Experience with biologics, antibody/protein sequence models, or protein language models.
 * Experience with active learning, Bayesian optimization, or sequence-based generative models for molecular design.
 * Familiarity with biophysical/assay data and developability endpoints.
 * Experience with MLOps, experiment tracking, and model monitoring.
 * Familiarity with how ontologies or knowledge graphs support data reuse and AI-ready datasets.

This position will be based at one of our office locations in either Spring House, PA (strongly preferred), Titusville, NJ, or Raritan, NJ, USA; or Madrid, Spain. (No remote option.)

## Description

You will design robust featurization approaches and curate standardized, traceable, model-ready datasets from biologics assay, biophysical, sequence, and construct data. You operate at the interface between our data-generating and data-infrastructure partners and In Silico Discovery (ISD), ensuring the datasets and features you create strengthen ISD's molecular property models. This is an opportunity to shape how AI learns from every biologics experiment., Scientific Data Analysis & Enablement

 * Apply modern data science tools to explore, integrate, and characterize heterogeneous biologics discovery data (e.g., antibody/protein sequence, construct, assay, and biophysical data).
 * Work with discovery scientists to translate scientific questions and DMTL (design-make-test-learn) decision points into clear data and analytical requirements.
 * Identify data quality issues, biases, gaps, and risks such as leakage or distribution shift that could affect downstream modeling or scientific interpretation.
 * Support the effective use of data for molecule prioritization, risk identification, and hypothesis generation.

Featurization & Model-Ready Data

 * Develop featurization and model-ready datasets from biologics discovery data.
 * Work with data engineers to specify the features, labels, and levels of aggregation that models need, preserving raw representations where information matters.
 * Curate, document, and version datasets so modeling is reproducible and traceable.

Partnership, Rigor & Growth

 * Collaborate with ISD to hand off standardized, traceable training datasets and align on where Data Science enables versus where ISD owns modeling.
 * Partner with Discovery scientists to frame ML problems around real decision points in the design-make-test-learn (DMTL) cycle.
 * Work closely with ontology and MLOps colleagues so datasets carry consistent semantics and models move reliably from development into use.
 * Champion reproducibility, documentation, and responsible AI.

Why This Role Is Unique

This is an opportunity to apply ML where it truly moves the needle in biologics discovery - grounded in real assay and sequence data, tightly partnered with world-class molecular modeling, and with real room to grow your scope, technical leadership, and impact as you build a track record of delivery.