> Markdown version of [/jobs/ext/3994698-mes-systems-engineer](https://www.wearedevelopers.com/jobs/ext/3994698-mes-systems-engineer). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # MES Systems Engineer - **Company:** Lilly Lebanon Advanced Therapies LLC - **Location:** Lebanon, IN, United States - **Experience:** Expert - **Salary:** $66,000.0 - $158,400.0 - **Contract:** Permanent contract - **Skills:** Application Programming Interfaces (APIs), Agile Methodology, Release Management, System Testing, Information Technology, GXP - **Published:** October 28, 2026 - **Apply:** https://www.dice.com/job-detail/492f318c-6f84-437f-a8ec-a5e8348217c5 ## About the Role Must have Strong Analytical and Problem-solving skills. Must have Excellent communication skills. What You Should Bring: Deep knowledge and experience with Manufacturing Execution Systems Understanding of regulatory requirements in GMP (Good Manufacturing Practice), such as FDA regulations for pharmaceutical manufacturing. Solid knowledge of Computer System Validation process Demonstrated ability to analyze, anticipate, and resolve complex issues (technical, operational, or business-related) through sound problem-solving skills Effectively prioritize and escalate issues Demonstrated learning agility and curiosity Demonstrated ability to understand quality control business processes and convert into IT requirements/solutions Basic Qualifications: Bachelor Degree in one of following disciplines - Science degree in IT, Chemistry, Pharmacy, Science or Engineering. At least 5 year of relevant work experience in MES and DCS integration Experience working in a GXP regulated environment. Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1. Additional Preferences: Previous Agile experience. Other Information: Role is Monday through Friday and based on-site. Must be flexible in providing support to accommodate other inputs (production schedules, shutdowns, etc.). Occasional extended hour and / or off-hour work may be required. Position will be based out of the Lebanon, IN site with ability to travel to other US and global Lilly sites as required. ## Description As an MES System Engineer your main function will be to Design, Develop, Deliver, and Qualify the MES solution for the Facility. You will also partner with the process automation, Process Operations Teams, and Global Tech at Lilly teams to determine innovative ways to implement and support MES recipes, systems, and components related to manufacturing execution and excellence. How You'll Succeed: Ensure site operational readiness from MES and Digital Execution Strategy Dynamically adapt project road map to site evolution/strategic directions, and new trends/issues. Partner cross functionally and build relationships with local and global teams to establish and implement the site IT roadmap Establish a strong site culture grounded in Lilly values, expectations, and operational excellence standards. Execute the MES design, implementation, and support strategy for Lebanon API. Proactively influence the business towards replication & standardization to drive value and implement the appropriate technical solutions. Ensure project and/or validation documentation is maintained during lifecycle & release management. Develops / assists in the creation and maintenance of the MES interfaces with other Lilly systems Coordinate with the business in gathering and understanding their requirements and translate them into an appropriate solution within the MES system Build and maintain awareness and knowledge of regulatory, legal, or quality requirements impacting the batch requirements, and ensure that solution requirements comply Ensure systems remain in a validated state and manage their lifecycle through releases, recapitalization, and retirement Ensure the incident, problem, configuration, and change/release management are all accomplished in alignment with and understanding of business needs Acts as Tech at Lilly key contact SME for MES IT systems and be prepared to participate in and support site audits Develops training materials