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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Software Engineer - **Company:** SOPHiA GENETICS - **Location:** United States (Remote available) - **Experience:** Expert - **Salary:** $131,000 - $198,000 - **Contract:** Permanent contract - **Skills:** Application Programming Interfaces (APIs), Agile Methodology, Artificial Intelligence, Amazon Web Services, Computer Vision, Microsoft Azure, Cloud Computing, Data Files, Database Queries, Desktop Computing, Distributed Systems, Key Management, OpenAI, Standard Sql, Software Engineering, AI Infrastructure, Data Logging, Large Language Models, Google Vertex AI, Backend, AI Platforms, Kubernetes, Information Technology, Dynatrace - **Published:** October 19, 2026 - **Apply:** https://www.builtincolorado.com/job/senior-software-engineer-ii-ai-platform/11771971?handler=ApplyRedirect ## About the Role * BS/BTech (or higher) in Computer Science, Engineering or a related field. * 6+ years experience as an engineer building full-stack web applications as part of a cross-functional team. * 3+ years of experience working with SQL or other database querying language on large multi-table data sets. * 3+ years of experience acting as a trusted technical decision-maker in a team setting, solving for short-term and long-term business value. * 3+ years of experience coaching other engineers., * Experience building or operating production platform infrastructure, distributed systems, developer platforms, or other high-availability shared services. * Experience with LLM infrastructure, model gateways, foundation model APIs, or managed AI platforms such as AWS Bedrock, Azure OpenAI, Google Vertex AI, or similar technologies. * Strong experience with cloud infrastructure, preferably AWS, and technologies such as Kubernetes, containers, and infrastructure as a code * Experience designing observability and operational practices for production systems, including metrics, distributed tracing, logging, alerting, SLOs, dashboards and failure handling. * Experience designing APIs and self-service platform capabilities used by other engineering teams. * Experience with Identity, access control, secrets management, security and governance for shared infrastructure. * Experience with cost management, usage attribution, quotas, budgets, or capacity management for shared platforms. * Experience operating systems that handle sensitive or regulated data. * Ability to evaluate architectural tradeoffs across reliability, performance, security, cost, scalability and developer experience. Physical Requirements: Sitting for prolonged periods of time. Extensive use of computers and keyboard. Occasional walking and lifting may be required. ## Description As a Senior Software Engineer II on Aledade's AI Core Platform team, you will help build and operate the shared infrastructure that enables applications and AI agents across Aledade to securely and reliably access foundation models. You will work on the platform capabilities behind model access, including model gateways, cloud AI services, provider integrations, routing and fallback, usage controls, observability, reliability, and model governance. We're looking for engineers who think beyond implementing individual features and consider the full lifecycle of production platform systems: architecture, scalability, failure modes, security, observability, operational readiness, cost, and developer experience. You will help evolve the platform as AI adoption grows across Aledade, building reusable and self-service capabilities rather than one-off solutions. You will work closely with engineers, product partners, security, infrastructure teams, and teams building AI applications and agents. Successful engineers in this role are comfortable operating in ambiguous problem spaces, making pragmatic technical decisions, and building secure, maintainable, observable, and resilient systems. Primary Duties: * Develop and implement scalable and performant solutions. * Partner, as a peer, with Engineering Managers, Product Managers, and stakeholders throughout Aledade to develop and execute technical roadmaps using Agile processes. * Mentor and coach more junior engineers including thorough pull request reviews for other developers and be receptive to critical feedback on your own work., Lead biopharma business development across the US West Coast and Central States, acquiring pharmaceutical and biotechnology customers and expanding strategic accounts. Build and manage Salesforce pipeline, develop proposals, negotiate agreements, and close projects involving genomic assays, biomarker discovery, clinical trial assays, precision medicine, and companion diagnostics. Collaborate with scientific, commercial, and operational teams to shape customer solutions. Travel domestically and internationally approximately 30% of the time. Top Skills: Companion Diagnostics (Cdx)Next-Generation Sequencing (Ngs)SalesforceSophia Ddm What you need to know about the Colorado Tech Scene With a business-friendly climate and research universities like CU Boulder and Colorado State, Colorado has made a name for itself as a startup ecosystem. The state boasts a skilled workforce and high quality of life thanks to its affordable housing, vibrant cultural scene and unparalleled opportunities for outdoor recreation. Colorado is also home to the National Renewable Energy Laboratory, helping cement its status as a hub for renewable energy innovation. Key Facts About Colorado Tech * Number of Tech Workers: 260,000; 8.5% of overall workforce (2024 CompTIA survey) * Major Tech Employers: Lockheed Martin, Century Link, Comcast, BAE Systems, Level 3 * Key Industries: Software, artificial intelligence, aerospace, e-commerce, fintech, healthtech * Funding Landscape: $4.9 billion in VC funding in 2024 (Pitchbook) * Notable Investors: Access Venture Partners, Ridgeline Ventures, Techstars, Blackhorn Ventures * Research Centers and Universities: Colorado School of Mines, University of Colorado Boulder, University of Denver, Colorado State University, Mesa Laboratory, Space Science Institute, National Center for Atmospheric Research, National Renewable Energy Laboratory, Gottlieb Institute