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# MST Senior Scientist

- **Company:** Cytovance Biologics, Inc.
- **Location:** Oklahoma City, OK, United States
- **Experience:** Expert
- **Contract:** Permanent contract
- **Skills:** Analysis of Variance (ANOVA), Failure Mode Effects Analysis, Statistical Hypothesis Testing, Statistical Process Control (SPC), Ishikawa
- **Published:** October 17, 2026
- **Apply:** https://www.careerbuilder.com/job-details/mst-senior-scientist-oklahoma-city-ok--4e1693e2-a974-4b03-bc2c-d58ad4635a70

## About the Role

Cross-Functional, Technical Leadership, Regulatory Compliance, Identify Issues, GMP (Good Manufacturing Practices), Continuous Improvement, Manufacturing, Manufacturing/Industrial Processes, Process Development, Writing Skills, * Strong knowledge of upstream cell culture and/or microbial fermentation and downstream purification; downstream expertise preferred.

 * Deep understanding of process scale-up principles including mixing, oxygen transfer, chromatography, filtration (terminal, viral, depth), UF/DF, and centrifugation.
 * Experience supporting GMP manufacturing and MSAT workflows.
 * Knowledge of process validation, process characterization, statistical analysis, and risk management.
 * Experience preparing technical reports, protocols, investigations, and client-facing documentation.

Experience with Some of Root Cause Analysis & Investigation Tools

 * 5 Whys
 * Fishbone (Ishikawa/5M or 6M) Diagram
 * Fault Tree Analysis (FTA)
 * Failure Modes and Effects Analysis (FMEA)
 * Pareto Analysis
 * Control Charts (SPC)
 * Trend Analysis
 * Process Capability Analysis
 * Hypothesis Testing (t-test, ANOVA, chi-square as appropriate), * BS, MS, or PhD in Chemical Engineering, Biochemical Engineering, Bioengineering, Biochemistry, Biology, Microbiology, or related discipline.
 * Minimum 10 years of biopharmaceutical industry experience with 5 years in MSAT
 * Demonstrated experience in MSAT, technology transfer, scale-up, and manufacturing support.
 * Ability to independently lead technical investigations and make sound scientific decisions.
 * Excellent technical writing skills for protocols, reports, and investigations.
 * Strong project management and organizational skills.

Leadership & Interpersonal Competencies

 * Excellent communication and presentation skills.
 * Build trust across cross-functional teams.
 * Professional, collaborative, and customer-focused.
 * Able to influence without direct authority.
 * Comfortable interacting with clients and senior management.
 * Strong analytical thinking and sound technical judgment.

## Description

This role serves as an independent technical leader responsible for technology transfer, process scale-up, manufacturing support, process troubleshooting, and continuous improvement for commercial and clinical biopharmaceutical manufacturing. The individual will lead cross-functional activities from process transfer through GMP manufacturing while ensuring technical rigor, regulatory compliance, and successful execution.

Essential Responsibilities

 * Lead technology transfer from clients and internal Process Development into GMP manufacturing.
 * Author comprehensive Technology Transfer Protocols that provide sufficient technical detail for manufacturing batch record development.
 * Develop process descriptions, manufacturing instructions, engineering calculations, and scale-up strategies.
 * Perform process scale-up calculations for upstream and downstream operations and select scientifically justified scale-up parameters.
 * Identify technical risks associated with scale-up and develop mitigation strategies.
 * Generate, review, and approve Bills of Materials (BOMs); ensure technical accuracy because BOMs are provided to clients for approval and drive project cost.
 * Support batch record development and manufacturing execution.
 * Provide on-floor manufacturing support during engineering, clinical, PPQ, and commercial campaigns.
 * Lead deviation, OOS, and OOT investigations to scientifically determine root causes and implement effective CAPAs.
 * Support change controls, process validation, process characterization, comparability studies, and continuous improvement.
 * Serve as technical interface with Process Development, Manufacturing, QC, QA, Facilities, Supply Chain, Project Management, and clients.
 * Mentor junior engineers/scientists and provide technical leadership.