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# Sr. Manager, Bioinformatics

- **Company:** Illumina, Inc
- **Location:** San Diego, CA, United States (Remote available)
- **Experience:** Expert
- **Salary:** $170,600.0 - $255,800.0
- **Contract:** Permanent contract
- **Skills:** Data Analysis, Bioinformatics, Computational Biology, R (Programming Language), Python (Programming Language), Linux System Administration, Software Engineering, Information Technology
- **Published:** October 22, 2026
- **Apply:** https://illumina.wd1.myworkdayjobs.com/illumina-careers/job/US---California---San-Diego/Sr-Manager--Bioinformatics_43592-JOB-1

## About the Role

* Typically requires a Bachelor's degree and a minimum of 12 years of related experience, with 3-6 years of Management experience.
 * PhD in Bioinformatics, Computational Biology, Computer Science, Statistics, Genomics, or related scientific discipline, with 8+ years of relevant experience preferred
 * Demonstrated leadership experience managing bioinformatics teams and complex cross-functional programs.
 * Experience supporting regulated products, including IVD, CDx, FDA, IVDR, or similar regulatory frameworks.
 * Strong understanding of next-generation sequencing, genomics data analysis, and bioinformatics pipeline development.
 * Experience supporting customers, commercial teams, or external collaborators in the deployment and adoption of genomics products and bioinformatics solutions.
 * Proficiency with bioinformatics software development and analysis tools, including Python, R, and Linux-based environments.
 * Excellent communication, stakeholder management, and organizational leadership skills.

## Description

The Sr. Manager, Bioinformatics will lead a team of bioinformatics scientists supporting Illumina's Clinical Genomics portfolio, including oncology, reproductive health, and regulated clinical sequencing products. This leader will oversee bioinformatics activities supporting assay development, software releases, regulatory submissions, and product commercialization. The role will partner closely with cross-functional teams to deliver high-quality bioinformatics solutions that support product development and customer success., * Lead, mentor, and develop a team of bioinformatics scientists while fostering a culture of collaboration, innovation, and technical excellence.

 * Manage bioinformatics activities supporting Clinical Genomics product development, commercialization, and lifecycle management, including portfolio prioritization, resource allocation, and risk management across multiple programs.
 * Oversee development, validation, and deployment of analytical methods and bioinformatics workflows that support customer-facing software, assays, and regulated products.
 * Collaborate across R&D, Software Engineering, Biostatistics, Regulatory, Quality, Product Management, and Commercial teams to achieve program objectives and business goals.
 * Partner with customers, commercial teams, and external collaborators to support product adoption, provide bioinformatics expertise, troubleshoot complex technical challenges, and gather feedback to improve products and workflows.
 * Drive evaluation and adoption of new analytical approaches, technologies, and scalable bioinformatics solutions that advance product capabilities, operational efficiency, and customer value.
 * Listed responsibilities are an essential, but not exhaustive, list of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.