> Markdown version of [/jobs/ext/4322055-principal-automation-integration-engineer](https://www.wearedevelopers.com/jobs/ext/4322055-principal-automation-integration-engineer). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Principal Automation Integration Engineer - **Company:** Regeneron - **Location:** Menands, NY, United States - **Experience:** Expert - **Salary:** $103,300.0 - $168,500.0 - **Contract:** Permanent contract - **Skills:** Cyber Security, Health Information Management, Systems Analysis, Software Engineering, Systems Integration, Information Technology, Real Time Data, GXP - **Published:** October 12, 2026 - **Apply:** https://www.indeed.com/viewjob?jk=6082dd7ef7e76768 ## About the Role * Bachelor's degree in Computer Science, Chemical, Mechanical, or Electrical Engineering, ideally, along with 8+ years of relevant experience * Experience with OT applications, including SCADAs, HMIs, Historians, etc. * Core knowledge related to ISA S95 and S88 principles and IT/Automation integration * Familiarity with standing up large systems at the enterprise level * Familiarity with PLC communication, HMIs, computerized system design, and maintenance of automation process control infrastructure * Gowning and Physical Requirements: * Full cleanroom attire (Examples may include: including laundered undergarments, gown, facemask, hairnet, safety glasses, safety shoes and booties, latex gloves and the use of sanitizing agents during gowning process including IPA) * Ability to remove jewelry, make-up and nail adornments when wearing cleanroom attire ## Description At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly skilled, experienced Senior Automation Systems Integration Engineer with experience in real-time data collection and analysis to join a diverse team of engineers, developers, analysts, and administrators to design, implement, and support Data Acquisition and Analysis Systems. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide., * Design, develop, and implement software/hardware improvements to existing automated equipment and new equipment according to change control procedures * Perform troubleshooting and investigations relating to manufacturing deviations and anomalies associated with automated control systems * Develop and edit engineering design documents, technical evaluations, and test plans for cGMP process equipment while following GAMP 5 guidelines * Support small manufacturing, engineering, and validation projects * Provide support to process control and process monitoring equipment software design, commissioning, testing, and corrective action * Author or update system specifications and user and functional requirements specifications, and generate and execute Factory Acceptance Tests (FAT) and Site Acceptance Testing (SAT) protocols * Review cyber security vulnerabilities and risk pertaining to automation systems, software, and infrastructure * Create, modify, and maintain automation system documentation * Participate in rotational on-call schedule