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# Principal Programmer

- **Company:** GSK LLP
- **Location:** Waltham, MA, United States
- **Experience:** Expert
- **Salary:** $126,225.0 - $210,375.0
- **Contract:** Permanent contract
- **Skills:** Clean Code Principles, Agile Methodology, Artificial Intelligence, Data Analysis, Computer Programming, Information Engineering, R (Programming Language), Python (Programming Language), Machine Learning, SAS (Software), Programming Languages
- **Published:** October 27, 2026
- **Apply:** http://hbcu.com/cgi-bin/jobs/searchJobs.cgi?job_id=35292486

## About the Role

We are looking for professionals with these required skills to achieve our goals:

 * 5+ years of programming experience within the pharmaceutical, biotechnology, healthcare, or other regulated industry.
 * Experience programming in one or more languages such as SAS, R, Python, or a comparable programming language.
 * Experience supporting clinical trials, clinical development programs, or analysis of clinical research data.
 * Experience developing, validating, and maintaining custom programs, analyses, tables, figures, or listings.
 * Experience applying programming standards, quality control procedures, and regulatory requirements within a regulated environment.
 * Expertise in Oncology therapeutic area specific requirements like RECIST1.1.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

 * Experience collaborating with cross-functional stakeholders to deliver programming or data analysis solutions.
 * Experience guiding others in the use of Artificial Intelligence/Machine Learning (AI/ML) tools or applying these tools to improve efficiency
 * Experience contributing to internal technical discussions, forums, or external technical organizations
 * Experience contributing to department strategies and key technical initiatives through working groups or sub-teams
 * Demonstrated networking and collaboration across departments, divisions, and external partners
 * Experience facilitating integration across matrix teams and contributing to planning and execution of programming activities
 * Experience guiding teams and individuals, fostering continuous improvement, collaboration, and innovation
 * Expertise in Oncology therapeutic area specific requirements like RECIST1.1.
 * Strong expertise in CDISC standards and its application
 * Demonstrated proficiency in R.

#LI-GSK #AGTech

Skills
Agile Leadership, Agile Methodology, Clinical Development, Data Engineering, Data Science, Influencing Without Authority, Learning Agility, Problem Solving, Statistical Programming

## Description

We are seeking a Principal Programmer to join our Clinical Programming team, contributing to pipeline delivery across complex and pivotal studies. This role operates within an agile, squad-based environment, where you will lead study delivery, collaborate with cross-functional teams, and act as a technical mentor to ensure high-quality and timely outputs. Working closely with stakeholders across clinical, statistical, and operational functions, you will play a key role in bridging scientific requirements with technical solutions, supporting the successful execution of clinical development programmes within a global setting., * Independently lead programming activities for one or more studies, ensuring development, maintenance, and validation of complex analysis packages

 * Foster quality assurance by ensuring programming activities adhere to standards such as Good Programming Practices and CDISC standards.
 * Mentor junior programmers by providing guidance and support in technical programming tasks and industry best practices
 * Lead programming support for regulatory interactions (e.g., EMA, FDA)
 * Identify gaps and inefficiencies and recommend and implement innovative solutions aligned with standards and best practices
 * Establish and uphold governance frameworks, identify risks early and devise mitigation plans, ensuring timely escalation