> Markdown version of [/jobs/ext/4484117-senior-ai-full-stack-software-engineer](https://www.wearedevelopers.com/jobs/ext/4484117-senior-ai-full-stack-software-engineer). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Senior AI Full stack Software Engineer - **Company:** McKesson - **Location:** Columbus, OH, United States - **Experience:** Expert - **Contract:** Permanent contract - **Skills:** Artificial Intelligence, Amazon Web Services, Computer Vision, Microsoft Azure, Cloud Computing Security, DevOps, Python (Programming Language), Machine Learning, Node.Js, Performance Tuning, OpenAI, Tensorflow, Microsoft Copilot, Software Engineering, Web Application Frameworks, IBM Watson Health, Pytorch, LangChain, Fast Healthcare Interoperability Resources, Retrieval-Augmented Generation, Large Language Models, Prompt Engineering, Model Validation, Llamaindex, Caching, Backend, Agentic-AI, Containerization, Kubernetes, Information Technology, HuggingFace, Health Level Seven International, PydanticAI Framework, Claude, Semantic Kernel, Data Pipelines, Docker - **Published:** October 31, 2026 - **Apply:** https://www.juju.com/job/1_49F1EF3AB7D1442A8E6A5D213D9BE510-OH293500074 ## About the Role We are seeking a highly skilled and experienced Senior AI Full Stack Software Engineer to join our innovative team at CMM. This role involves designing, developing, and deploying end-to-end AI-powered solutions, from robust backend services to intuitive user interfaces, to enhance our healthcare and decision-making platforms. **Key Responsibilities** - Lead AI-Driven Healthcare Solutions: Design and deploy AI applications that support decision-making, patient engagement, and operational efficiency. - Integrate AI into EHRs and Clinical Systems: Build scalable systems that incorporate LLMs, voice/image recognition, and document parsing into existing healthcare ITinfrastructure. - Develop and Optimize Data Pipelines: Ensure secure, HIPAA-compliant data pipelines for training and deploying AI models using structured and unstructured healthcare data (e.g., clinical notes, imaging, lab results). - Model Evaluation and Compliance: Apply rigorous evaluation metrics (e.g., sensitivity, specificity, AUC-ROC) and ensure models meet regulatory and ethical standards. - Mentor and Lead: Guide junior engineers and contribute to the strategic direction of AI initiatives within the organization. - Rapid AI prototyping and iteration with product representatives to vet multiple concepts **We are unable to provide sponsorship for this role presently or in the future.** **Priority will be given to candidates who reside in the Columbus, OH and Atlanta, GA metropolitan area.** **Minimum Qualifications** - 10+ years of software engineering experience, with 4+ years in AI/ML development preferred. - B.S. degree in Computer Science or related engineering discipline, or equivalent experience **Critical Skills** - 2+ years of experience building AI solutions in healthcare or lifesciences. - Deep understanding of healthcare data standards (e.g., HL7, FHIR) and compliance frameworks (e.g., HIPAA, GDPR). - Healthcare AI Expertise: Proven ability to build AI models for clinical NLP, medical imaging, patient risk stratification, and carepersonalization. - LLM & RAG Systems: Skilled in building retrieval-augmented generation systems using tools likePydantic, Semantic Kernel,LangChain,LlamaIndex, and vector databases. - Experienced in creating custom AI agents or spec-driven tools. - Experience writing skills for Claude, Copilot, Codex etc. - Prompt Engineering & Optimization: Advanced techniques for prompt tuning, caching, and benchmarking. - Full Stack Development: Proficiency in Python, Node.js, and modern web frameworks. **Preferred Skills** Cloud & DevOps: Experience with secure cloud environments (AWS/GCP/Azure), containerization (Docker, Kubernetes), and CI/CD pipelines. AI Tooling: Familiarity with OpenAI, Hugging Face,PyDanticAI, TensorFlow,PyTorch, and healthcare-specific AI libraries. Communication & Leadership: Ability to communicate complex AI concepts to clinical and executive stakeholders and lead cross-functional teams. Experience mentoring and developing juniors in development an AI concepts/best practices.