> Markdown version of [/jobs/ext/4582921-system-engineer](https://www.wearedevelopers.com/jobs/ext/4582921-system-engineer). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md).

---

# System Engineer

- **Company:** System One
- **Location:** Cambridge, MA, United States
- **Experience:** Expert
- **Contract:** Temporary to permanent
- **Skills:** Systems Engineering, SolidWorks (CAD), Data Systems, Network Interface Controllers, Failure Mode Effects Analysis, Requirements Traceability, Systems Integration
- **Published:** November 5, 2026
- **Apply:** https://www.thejobnetwork.com/job/8793704b-00b8-4fed-9222-0ae934ec8d55/system-engineer

## About the Role

* BS or MS in Mechanical, Electrical, Mechatronic, Chemical, Biomedical Engineering, or a related engineering discipline.
 * 5+ years of systems engineering experience supporting multidisciplinary electromechanical products, ideally complex instrument or automated platform development.
 * Experience supporting at least one program through integration and successful demonstration, beyond the design-review stage.
 * Strong experience with:
 + Requirements capture and management
 + Interface definition and control
 + Verification planning and execution
 + Requirements traceability and associated tools
 + FMEA and technical risk management
 * Experience within a regulated hardware environment, such as medical devices, pharmaceutical process equipment, in-vitro diagnostics, or a comparable industry.
 * Working knowledge of SolidWorks, control-system design, PLC programming, and P&IDs.
 * Ability to maintain detailed requirements, interfaces, and traceability throughout a rapidly evolving development program.
 * Comfortable operating as the second Systems Engineer while independently owning a defined technical scope.
 * Excellent written and verbal communication skills.
 * Ability to work effectively across international, multidisciplinary, and multi-organizational teams while meeting aggressive project deadlines.

Preferred Qualifications

 * INCOSE training or certification.
 * Experience with single-use or cartridge-based instruments.
 * Experience with model-based systems engineering (MBSE).
 * Previous experience supporting federally funded development programs.
 * Biotechnology, biomanufacturing, or complex instrumentation experience involving the integration of hardware, controls, engineering, and biological processes.

## Description

Title: System Engineer Location: Onsite, Boston, MA Type: Contract to Hire Hours: Standard business hours Overview: Join a growing U.S. biotechnology organization supporting a federal initiative in next-generation RNA medicine manufacturing. Working alongside the Lead Systems Engineer, this role will own defined subsystems with a focus on requirements, interfaces, verification, traceability, risk management, and integration readiness across complex electromechanical and biotechnology platforms., * Own requirements capture, development, and management for an assigned group of subsystems.

 * Develop and maintain Interface Control Documents (ICDs), ensuring they remain current as system designs and requirements evolve.
 * Develop verification plans and maintain requirements-to-evidence traceability throughout the development lifecycle.
 * Facilitate FMEA activities and maintain an assigned portion of the program's risk, assumption, and tradeoff register.
 * Support development of the interface specification between the manufacturing and analytics systems.
 * Contribute to system-level size, weight, and power assessments.
 * Own an assigned portion of the integration readiness record and execute verification activities for assigned subsystems during the build and integration phases.
 * Support subsystem and system-level integration, troubleshooting, testing, and demonstration activities.
 * Apply engineering design skills within a SolidWorks environment and collaborate with design engineering teams.
 * Support control-system design and PLC programming as required for assigned subsystems.
 * Develop, review, and maintain Process & Instrumentation Diagrams (P&IDs).
 * Work closely with the Lead Systems Engineer and multidisciplinary technical teams to identify and resolve interface, integration, and verification issues.
 * Maintain accurate requirements and traceability documentation throughout the program rather than recreating documentation ahead of formal design reviews.