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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Head of Global Manufacturing Science & Technology - **Company:** Legend Biotech - **Location:** Bridgewater, NJ, United States - **Experience:** Expert - **Salary:** $271,800 - **Contract:** Permanent contract - **Skills:** Data Analysis, Data Processing, Data Analytics - **Published:** November 7, 2026 - **Apply:** https://www.careerbuilder.com/job-details/head-of-global-manufacturing-science-technology-bridgewater-nj--b36d2122-c23d-4210-9144-42b4724faa74 ## About the Role * Advanced degree, preferably PhD in Chemical Engineering, Biological Sciences, Pharmaceutical Sciences, or related discipline. * 20+ years of progressive experience in MSAT, process development, manufacturing science, technical operations, or related biopharmaceutical functions, including significant global leadership experience. * Proven global experience leading MSAT for commercial biopharmaceutical products, preferably including cell therapy, gene therapy, or other advanced modalities. * Strong expertise in process characterization, validation, technology transfer, CPV, process optimization, manufacturing technology, and lifecycle management. * Proven ability to lead complex technical decisions across R&D, CMC, Manufacturing, Quality, Regulatory, Engineering, and Supply Chain. * Enterprise technical leadership with strong business judgment. * Strong strategic thinking combined with technical depth. * Executive presence and ability to influence across functions and organizational boundaries. * Data-driven, scientifically rigorous, and highly pragmatic. * Strong innovation and continuous improvement mindset. * Develops people, builds capabilities, and creates a culture of technical excellence, accountability, and innovation. #Li-BZ1 ## Description Global MSAT Strategy & Technical Leadership * Define and execute the global MSAT strategy and operating model aligned with business, portfolio, and manufacturing priorities. * Establish global technical standards, capabilities, and governance for manufacturing processes across internal and external sites. * Serve as the senior technical authority for process capability, robustness, scalability, and manufacturing performance. Process Technology & Manufacturing Performance * Own the technical strategy for process characterization, validation, process capability, continued process verification, and process monitoring. * Drive consistency and systematic improvement of manufacturing processes to increase yield, reliability, capacity, throughput, consistency, and cost efficiency. * Provide technical leadership for manufacturing investigations, process deviations, and recurring performance issues. * Establish science- and data-based approaches to identify process risks and proactively improve manufacturing performance. Technology Transfer & Commercialization * Provide MSAT leadership for technology transfer and manufacturing readiness from development into commercial operations. * Ensure effective transfer of process knowledge, control strategies, technical standards, and manufacturing capabilities into internal and external manufacturing networks. * Partner with CMC and R&D to ensure development programs are designed for commercial scalability, manufacturability, and process robustness. * Provide technical input to major manufacturing network, capacity, and commercialization decisions. Lifecycle Management & Continuous Improvement * Own the MSAT strategy for the technical lifecycle of commercial products, including process improvements, scale-up/scale-out, site transfers, capacity expansion, and manufacturing optimization. * Identify and prioritize opportunities to improve quality, yield, throughput, cost, cycle time, and supply resilience. * Lead implementation of advanced process technologies, automation, modeling, analytics, and digital manufacturing capabilities. * Ensure manufacturing knowledge and process data are systematically leveraged to drive continuous improvement. Manufacturing & Global Network * Provide technical leadership, support and governance for MSAT activities at internal sites, CMOs/CDMOs and other external manufacturing partners. * Ensure consistent technical standards, process understanding, technology transfer, and lifecycle management across the global manufacturing network. * Partner with Manufacturing leadership to resolve technical, process, and performance issues. Innovation, Digital & Advanced Manufacturing * Establish the strategic roadmap for advanced manufacturing technologies, automation, digital manufacturing, process analytics, and data science. * Accelerate adoption of emerging technologies that improve manufacturing control, predictability, flexibility, and efficiency. * Promote the use of data-driven and predictive approaches to enhance process understanding and manufacturing performance. Executive Leadership & Organization * Build and lead a high-performing global MSAT organization with the technical depth and capabilities required to support a growing pipeline and commercial portfolio. * Develop organizational capabilities, talent, succession, and technical leadership across the global manufacturing network. * Serve as a senior member of the Global Manufacturing & Supply Leadership Team, contributing to manufacturing strategy, investment decisions, portfolio priorities, and supply resilience. * Act as a trusted technical advisor to senior leadership on major manufacturing, technology, process, and investment decisions. * Represent the company with strategic partners, regulators, industry organizations, and external technical forums., Applicants must be authorized to work in the United States. As part of our commitment to maintaining a lawful workforce and ensuring compliance with federal employment regulations, we participate in the E-Verify program. If you are selected for employment, you will be required to complete the Form I-9 process, and your employment eligibility will be verified through E-Verify in accordance with applicable federal law. We are committed to providing a fair, transparent, and welcoming hiring experience for all candidates.