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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Senior MES Platform Engineer (Manufacturing Execution System) - **Company:** GSK - **Location:** Ware, United Kingdom - **Experience:** Expert - **Contract:** Permanent contract - **Skills:** Agile Methodology, Artificial Intelligence, Microsoft Azure, Cloud Computing, Configuration Management, Cyber Security, Computer Programming, Databases, Continuous Integration, Network Security, Windows Servers, Release Management, Cloud Services, Software Engineering, System Testing, Virtual Machines, Technical Debt, Infrastructure as Code (IaC), Build Management, Containerization, Information Technology, Syncade, Enterprise Integration, Data Management, Industrial Software, Software Version Control, Api Management, GXP, Microservices - **Published:** November 12, 2026 - **Apply:** https://gsk.wd5.myworkdayjobs.com/GSKCareers/job/UK---Hertfordshire---Ware/Senior-MES-Platform-Engineer--Manufacturing-Execution-System-_451058-1 ## About the Role This role would suit a highly motivated person who has strong experience of designing, developing, and validating AI-enabled digital solutions and Smart Manufacturing capabilities within complex manufacturing and business environments. You will have strong technical knowledge obtained from working in a highly-regulated industry. You will have demonstrably strong people skills, be resilient and calm under pressure, have a strong continuous improvement mindset, and a proven ability to drive performance while managing multiple stakeholders., * Relevant Degree (eg; Computer Science, Software Engineering, Data Science, Artificial Intelligence, Engineering, Information Technology, Manufacturing Systems, or related technical discipline). * Strong experience in manufacturing technology, Manufacturing Execution System (MES), industrial software, platform engineering, infrastructure and / or a related discipline. * Experience with MES, historian or manufacturing data technologies (eg; Siemens Opcenter, AspenTech manufacturing solutions, Emerson Syncade, Aspen IP.21 or comparable platforms). * Experience operating within regulated manufacturing environments and applying GxP, GAMP, computer system validation and change-control expectations. * Experience working directly with business stakeholders to identify, shape, and deliver technology solutions (including directing technical work performed by contractors, system integrators or specialist suppliers. * Practical experience using approved AI tools to improve productivity and ways of working, with sound judgement in validating outputs and compliance with Responsible AI, privacy and security requirements. We welcome people who bring curiosity, humility and a practical approach. We are committed to inclusion and to creating a supportive environment where everyone can grow. If you enjoy solving real problems, delivering measurable results, and helping teams succeed, we encourage you to apply. If you would like to learn more about our company wide benefits and life at GSK we would suggest looking at our webpage Life at GSK | GSK. #AGTech Skills Agile Methodology, API Management, CI/CD, Cloud Based Services, Computer Programming, Configuration Management (CM), Containerization, Database Management, Infrastructure As Code (IaC), Microservices Architecture, Network Security, Operating Systems (OS), System Monitors, Version Control System ## Description We are looking for a Technical Specialist (Senior MES Platform Engineer) to join our Global Supply Chain (GSC) Digital and Technology function. The GSC Digital and Technology function spearheads the implementation of integrated digital solutions and AI into the supply chain (including Smart Manufacturing, Enterprise Resource Planning - ERP - Evolution and broader supply chain technology and data capabilities)., The Senior MES Platform Engineer provides technical expertise for the lifecycle, reliability, compliance and continuous evolution of global Manufacturing Execution System (MES) platforms and associated manufacturing data technologies. The role turns the technical roadmap and platform backlog into robust designs and executable delivery plans for upgrades, vendor releases, infrastructure changes, remediation and standardisation. It assesses technical options, defines reusable engineering patterns, reviews contractor designs and ensures that solutions are secure, scalable, validated, supportable and aligned with enterprise architecture and manufacturing technology standards. The position works across several platforms, including Siemens Opcenter, AspenTech manufacturing solutions, Emerson Syncade, and Aspen IP.21. Working closely with the Global MES Platform Manager, MES Platform Manager, Product Owners, Architects, Infrastructure and Cloud teams, Computer System Validation, Quality, Cyber Security, Service Management, vendors and delivery partners, the role provides hands-on technical leadership to coordinates complex engineering activities and lead technical troubleshooting. This includes ensuring effective documentation and knowledge transfer from external contractors to the internal organisation. Key Responsibilities (include..,): * Translate the MES technical roadmap and platform backlog into solution designs, engineering work packages, implementation plans and technical acceptance criteria. Manage technical assessment of vendor releases, patches, support requirements, infrastructure dependencies and obsolescence risks. * Design and review platform upgrades and major changes across application, database, operating system, integration and hosting layers. Define and maintain reusable platform configurations, engineering standards, reference patterns, installation approaches and technical documentation. * Provide senior engineering expertise across Azure, virtual machines, on-premises hosting, Windows Server, databases, networks, backup, recovery, monitoring and platform integrations. * Partner with Solution and Enterprise Architects to ensure designs are integrated, scalable, resilient, secure, supportable and aligned with enterprise standards. Work with Computer System Validation and Quality teams to assess validation impact and ensure that design, build, test and release evidence supports GxP, Good Automated Manufacturing Practice (GAMP) and applicable quality requirements. * Ensure platform changes follow required controls for cyber security, data protection, change management, service readiness, operational resilience and records management. * Manage technical delivery performed by contractors, system integrators and specialist suppliers, including design reviews, quality checks, issue resolution, documentation and knowledge transfer. Act as a technical interface with software vendors and delivery partners, challenge proposed solutions and clarify product behaviour, defects, limitations and upgrade requirements. * Manage complex troubleshooting across application and infrastructure layers, identify root causes and drive sustainable remediation. Support release planning, environment readiness, installation, configuration, testing, cutover, hypercare and transition into support. * Maintain visibility of technical risks, dependencies, technical debt, supportability and lifecycle status, and escalate material issues to the MES Platform Manager. * Coach the MES Platform Engineer and contractor resources, sharing knowledge and promoting consistent engineering practices. Identify opportunities for standardisation, automation, simplification and reuse across MES, historian and manufacturing data platforms. * Use approved AI tools in day-to-day work to improve personal productivity and the team's ways of working, sharing effective practices and applying sound judgement, including validating outputs and following GSK's Responsible AI, privacy and security requirements. Automate and version-control installation, configuration and environment builds, and test upgrades and patches before release. * Protect site operations through platform availability, upgrade success and inspection readiness, measured by uptime and reduced obsolescence risk.