> Markdown version of [/jobs/ext/48227-sr-engineer-dsp](https://www.wearedevelopers.com/jobs/ext/48227-sr-engineer-dsp). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Sr. Engineer - DSP - **Company:** DMC Inc - **Location:** Boulder, CO, United States - **Experience:** Expert - **Salary:** $125,000.0 - $155,000.0 - **Contract:** Permanent contract - **Skills:** Microsoft Excel, Data Analysis, Data Integrity, Failure Mode Effects Analysis, R (Programming Language), Python (Programming Language), Enterprise Software Applications - **Published:** May 22, 2026 - **Apply:** https://www.indeed.com/viewjob?jk=50ee9148d5612b8d ## About the Role Do you have experience in Technical writing within manufacturing?, Do you have a Bachelor's degree?, * B.S. or higher in Chemical Engineering, Biochemical Engineering, Bioengineering, or a related discipline. * 5+ years (B.S.) or 0-2 years (M.S./Ph.D.) of relevant experience in small molecule purifications, bioprocessing, or process development (industry or strong graduate/lab experience). * Hands-on experience with one or more of the following: + Chromatography (resin screening, column packing, scale-down models) + TFF/UFDF systems (membrane selection, flux optimization, shear sensitivity, fouling mitigation) + Crystallization (solubility studies, process design, solid-liquid-separation methods) + Continuous process modeling (using advanced software packages or manually) * Proficiency in experimental design and data analysis (Python, R, Excel, etc.) * Strong technical writing skills, * Experience with scale-up/tech transfer and/or supporting manufacturing campaigns. * Knowledge of process characterization, risk assessment (FMEA), and concepts such as QbD. * Availability to travel * Experience developing cost-of-goods (COGs) awareness and capacity/throughput assessments. * Comfort with lab safety practices, equipment maintenance, and methodical troubleshooting. ## Description We are seeking a Chemical Engineer to join our Downstream Processing (DSP) Development team, focused on bench-scale process development for biologics/bioproducts and the translation of those processes to pilot and commercial manufacturing. You will design and execute experiments at bench scale (e.g., mL-L), develop robust purification steps (chromatography, filtration, precipitation, etc.), and work cross-functionally to transfer your process to industrial scale. This role is ideal for an engineer who enjoys hands-on lab work, rigorous data analysis, and solving scale-up challenges with the end goal of commercializing processes at industrial scale. Traveling to partner sites for troubleshooting and overseeing tech-transfer is likely., * Bench-scale process development and optimization. * Design, execute, and analyze experiments using purification unit operations (e.g., depth filtration, centrifugation, TFF/UFDF, chromatography, precipitation, etc.). * Build methods and strategies to define scalable operating ranges, identify critical process parameters, and improve yield, purity, and throughput for purification unit operations. * Support tech transfer to internal or external manufacturing sites, including documentation, protocols, and general transfer of process knowledge. * Translate bench-scale findings into continuous models to predict process flow rates, unit sizes, and overall process costs. * Author and review development reports, batch records, protocols, and technical assessments to enable stage gates * Maintain high standards for data integrity, traceability, and reproducibility; ensure experiments and documentation align with internal quality systems and regulatory expectations. * Collaborate with Upstream, Analytical, Quality, Regulatory, and Business teams to ensure end-to-end process performance and timeline execution. * Communicate results clearly in team meetings and technical reviews; present recommendations backed by data and risk-based reasoning. ## Related Videos - [In-depth .NET Azure Functions: Isolated mode, performance and durable AI agents](https://www.wearedevelopers.com/videos/100207-in-depth-net-azure-functions-isolated-mode-performance-and-durable-ai-agents) - [Exploring 5 Key Applications of AI Abundance with Blockchain Assurance](https://www.wearedevelopers.com/videos/971-exploring-5-key-applications-of-ai-abundance-with-blockchain-assurance) - [Data Science in Retail](https://www.wearedevelopers.com/videos/586-data-science-in-retail) - [The ABC of DX](https://www.wearedevelopers.com/videos/727-the-abc-of-dx) - [From Syntax to Singularity: AI’s Impact on Developer Roles](https://www.wearedevelopers.com/videos/900-from-syntax-to-singularity-ai-s-impact-on-developer-roles) - [Startup Presentation: StorX - Future of Cloud Storage](https://www.wearedevelopers.com/videos/1176-startup-presentation-storx-future-of-cloud-storage) ## Related Articles - [Why developer experience matters](https://www.wearedevelopers.com/magazine/514-why-developer-experience-matters) - [Data Engineer Salary UK](https://www.wearedevelopers.com/magazine/253-data-engineer-salary-uk) - [From developer to manager – what does it take to become an engineering manager?](https://www.wearedevelopers.com/magazine/42-from-developer-to-manager-what-does-it-take-to-become-an-engineering-manager) - [Dev Digest 212: WebMCP or MCP, What is DevRel, AI's 10% Productivity Boost, and a 49MB Web Page…](https://www.wearedevelopers.com/magazine/717-dev-digest-212-webmcp-or-mcp-what-is-devrel-ai-s-10-productivity-boost-and-a-49mb-web-page) - [Fully Remote Software Engineer Jobs](https://www.wearedevelopers.com/magazine/447-fully-remote-software-engineer-jobs) - [Where To Find Software Engineering Jobs](https://www.wearedevelopers.com/magazine/396-where-to-find-software-engineering-jobs)