> Markdown version of [/jobs/ext/543111-telecommute-net-project-manager-mes-medical-devices-life-sciences](https://www.wearedevelopers.com/jobs/ext/543111-telecommute-net-project-manager-mes-medical-devices-life-sciences). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # TELECOMMUTE .NET Project Manager - MES (Medical Devices / Life Sciences) - **Company:** Usg Inc. - **Location:** Pittsburgh, PA, United States (Remote available) - **Experience:** Expert - **Contract:** Permanent contract - **Skills:** ASP.NET, .NET Framework, Agile Methodology, C Sharp (Programming Language), Data Integrity, Supervisory Control and Data Acquisition (SCADA), Scrum Methodology, Systems Development Life Cycle, System Testing, Systems Integration, Iq/oq/pq, Blazor - **Published:** June 10, 2026 - **Apply:** https://www.dice.com/job-detail/60015f2e-6de1-4bad-b0f9-a006c1b90141 ## About the Role Technical Expertise * 10+ years of strong proficiency in: * C#, ASP.NET, .NET CoreSQL ServerWPF or Blazor (for HMI/Dashboard development) * 5+ years of experience with MES architecture and shop floor system integration (PLCs, SCADA). Domain Experience * Proven experience managing MES implementations in: * Life SciencesMedical Devices (Class II/III preferred) Certifications * PMP (Project Management Professional) OR Certified Scrum Master (CSM)Strong understanding of Quality Management Systems (QMS) * Regulatory Knowledge * Familiarity with: + FDA 21 CFR Part 11GAMP standardsISO 13485FDA Design Controls Validation Expertise * Hands-on experience with Computer System Validation (CSV)Strong documentation and audit readiness experience Key Skills * Strong leadership and stakeholder managementExcellent communication and reporting skillsRisk assessment and mitigation expertiseAnalytical and problem-solving mindsetAbility to manage complex, regulated projects Preferred Qualifications * Experience with eDHR implementationsExposure to digital transformation initiatives in manufacturingKnowledge of cybersecurity frameworks in regulated environments * Initiatives in manufacturingKnowledge of cybersecurity frameworks in regulated environments ## Description We are seeking an experienced Project Manager (PM) to lead the implementation and delivery of Manufacturing Execution Systems (MES) within a highly regulated medical devices/life sciences environment. This role requires strong technical expertise, regulatory knowledge, and leadership capabilities to manage cross-functional teams and ensure compliance with FDA and industry standards. Key Responsibilities Project Planning & Execution * * Define project scope, objectives, and deliverables in collaboration with senior management and key stakeholders.Develop comprehensive project plans including timelines, milestones, and resource allocation.Drive end-to-end execution of MES implementation projects, ensuring alignment with organizational goals. * Budget & Resource Management * Forecast project requirements and manage budgets effectively.Track project expenses and identify/mitigate variances proactively.Optimize resource utilization across teams and project phases. Team Leadership & Delivery * Lead cross-functional teams including software engineers, automation specialists, and QA teams.Delegate tasks effectively, ensuring accountability and high performance.Drive delivery using Agile or hybrid SDLC methodologies. * Risk Management & Compliance * Identify and mitigate project risks, issues, and bottlenecks.Ensure adherence to cybersecurity, data integrity, and validation requirements.Maintain audit trails and ensure compliance with Device History Records (DHR) requirements. Stakeholder Communication * Act as the primary point of contact for stakeholders.Provide regular status updates, performance metrics, and executive reports.Facilitate communication between business, IT, and manufacturing teams. Quality Assurance & Project Closeout * Ensure project deliverables meet quality, regulatory, and organizational standards.Oversee post-implementation validation and documentation.Conduct post-project reviews to identify continuous improvement opportunities. Compliance & Validation * Lead Computer System Validation (CSV) processes ensuring all MES applications meet regulatory standards.Ensure compliance with FDA 21 CFR Part 11 and GAMP guidelines.Manage validation documentation including IQ/OQ/PQ protocols. Shop Floor Integration * Oversee integration of .NET-based MES systems with plant floor systems (PLCs, SCADA).Enable connectivity between manufacturing operations and enterprise systems (ERP).Ensure traceability for production metrics and genealogy tracking. eDHR Implementation * Lead transition from paper-based systems to Electronic Device History Records (eDHR).Collaborate closely with IT, Quality, and Manufacturing teams to ensure seamless adoption. ## Related Videos - [Blazor Unleashed: The Future of .NET Web Development](https://www.wearedevelopers.com/videos/1564-blazor-unleashed-the-future-of-net-web-development) - [Remote Driving on Plant Grounds with State-of-the-Art Cloud Technologies](https://www.wearedevelopers.com/videos/251-remote-driving-on-plant-grounds-with-state-of-the-art-cloud-technologies) - [Building Multi-Tenant ASP.NET Core Applications: Best Practices and Real-World Solutions](https://www.wearedevelopers.com/videos/1552-building-multi-tenant-asp-net-core-applications-best-practices-and-real-world-solutions) - [Blazor – the new SPA Framework for everyone who hates JavaScript](https://www.wearedevelopers.com/videos/699-blazor-the-new-spa-framework-for-everyone-who-hates-javascript) - [Developing ASP.NET Core Microservices with Dapr: A practical guide](https://www.wearedevelopers.com/videos/1528-developing-asp-net-core-microservices-with-dapr-a-practical-guide) - [ZEISS & Microsoft - Building the Next Generation Medical Ecosystem in the Cloud](https://www.wearedevelopers.com/videos/424-zeiss-microsoft-building-the-next-generation-medical-ecosystem-in-the-cloud) ## Related Articles - [How We Built a Worry-Free System That Runs for 10+ Years – And What We’d Do Again](https://www.wearedevelopers.com/magazine/751-how-we-built-a-worry-free-system-that-runs-for-10-years-and-what-we-d-do-again) - [Fully Remote Software Engineer Jobs](https://www.wearedevelopers.com/magazine/447-fully-remote-software-engineer-jobs) - [Best Coding Boot Camps in Germany](https://www.wearedevelopers.com/magazine/237-best-coding-boot-camps-in-germany) - [Dev Digest 121 - AI goes offline](https://www.wearedevelopers.com/magazine/456-dev-digest-121-ai-goes-offline) - [Is Software Engineering Over-Saturated?](https://www.wearedevelopers.com/magazine/418-is-software-engineering-over-saturated) - [Mastering Remote Work: Tips for Developers](https://www.wearedevelopers.com/magazine/558-mastering-remote-work-tips-for-developers)