> Markdown version of [/jobs/ext/559237-principal-statistical-programmer-global-studies-remote](https://www.wearedevelopers.com/jobs/ext/559237-principal-statistical-programmer-global-studies-remote). Every page supports `.md` or `Accept: text/markdown`. Links point to the HTML versions so they work for humans too. Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md).

---

# Principal Statistical Programmer - Global Studies- REMOTE

- **Company:** Penfield Search Partners
- **Location:** Fairfield, CT, United States (Remote available)
- **Experience:** Expert
- **Contract:** Permanent contract
- **Skills:** Clean Code Principles, Computer Programming, R (Programming Language), SAS (Software), Information Technology
- **Published:** June 14, 2026
- **Apply:** https://www.indeed.com/viewjob?jk=d585e3f1ab20b421

## About the Role

Do you have experience in SAS language?, Do you have a Master's degree?, * Strong expertise in CDISC standards, including ADaM and SDTM

 * Demonstrated experience reviewing specs and ensuring high-quality, submission-ready deliverables
 * Working experience in LSAF environment
 * Experience validating CRO programming deliverables
 * Ability to operate with increased performance accountability and ownership
 * Strong CRO-facing communication and collaboration skills
 * Proven ability to manage multiple global studies simultaneously

Additional Requirements

 * Practical experience with multiple imputation (MI), particularly under Missing at Random (MAR) assumptions
 * Familiarity with the estimands framework (ICH E9 R1) and managing intercurrent events (ICEs) within ADaM domains using various strategies, * Bachelor's or Master's degree in Statistics, Mathematics, Computer Science, or related field
 * 5+ years of SAS programming experience within pharmaceutical/biotech
 * Strong understanding of statistical methods used in clinical trial analysis
 * Knowledge of Good Programming Practices and GCP
 * Preferred: Experience with R programming

## Description

We are seeking a highly experienced Statistical Programmer to lead programming activities across global clinical studies. This role operates beyond executional programming, with responsibility for oversight of CRO deliverables, validation of outputs, and end-to-end accountability for statistical programming packages., * Lead statistical programming activities across global studies

 * Serve as primary programming lead in collaboration with Biostatistics
 * Develop, review, and validate SDTM and ADaM datasets in accordance with CDISC standards
 * Review specifications and proactively challenge inconsistencies in protocols, SAPs, and dataset definitions
 * Validate program outputs and ensure accuracy, quality, and regulatory compliance
 * Provide oversight and guidance to CRO partners, consolidating and communicating feedback effectively
 * Manage timelines, delivery packages, and milestone commitments
Contribute to continuous improvement of programming processes and standards


## Related Videos

- [Times of (climate) crisis - How and why sustainable software is a must!](https://www.wearedevelopers.com/videos/988-times-of-climate-crisis-how-and-why-sustainable-software-is-a-must)
- [Photonic Computing: Programming a New Class of AI Accelerators (incl. Live Coding)](https://www.wearedevelopers.com/videos/100196-photonic-computing-programming-a-new-class-of-ai-accelerators-incl-live-coding)
- [Building software that scales with Typescript](https://www.wearedevelopers.com/videos/415-building-software-that-scales-with-typescript)
- [Why Your Next Best Talent Might Not Be in Your Neighborhood](https://www.wearedevelopers.com/videos/1861-why-your-next-best-talent-might-not-be-in-your-neighborhood)
- [Kettle and Pot or Peas in a Pod? A Debate on Open-Source and Proprietary Software](https://www.wearedevelopers.com/videos/1585-kettle-and-pot-or-peas-in-a-pod-a-debate-on-open-source-and-proprietary-software)
- [Geometric deep learning for drug discovery](https://www.wearedevelopers.com/videos/264-geometric-deep-learning-for-drug-discovery)

## Related Articles

- [Fully Remote Software Engineer Jobs](https://www.wearedevelopers.com/magazine/447-fully-remote-software-engineer-jobs)
- [Best Job Boards for Remote Work for Developers](https://www.wearedevelopers.com/magazine/290-best-job-boards-for-remote-work-for-developers)
- [Résumé-Driven Development: How IT trends affect the job market for software developers](https://www.wearedevelopers.com/magazine/59-resume-driven-development-how-it-trends-affect-the-job-market-for-software-developers)
- [Data Analyst Salary in the UK](https://www.wearedevelopers.com/magazine/278-data-analyst-salary-in-the-uk)
- [Find a Developer Job: 12 Best Job Sites For Developers](https://www.wearedevelopers.com/magazine/165-find-a-developer-job-12-best-job-sites-for-developers)
- [10 Highest Paying Programming Languages 2025](https://www.wearedevelopers.com/magazine/150-10-highest-paying-programming-languages-2025)