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Agent guide: [/agents.md](https://www.wearedevelopers.com/agents.md). --- # Senior Director, Real World Evidence (Center of Excellence Lead) - **Company:** Crinetics Pharmaceuticals, Inc. - **Location:** United States (Remote available) - **Experience:** Expert - **Salary:** $280,000.0 - $308,000.0 - **Contract:** Franchise - **Skills:** Artificial Intelligence, Biometrics, Databases, Data Governance, Data Infrastructure, Electronic Medical Records - **Published:** June 12, 2026 - **Apply:** https://www.indeed.com/viewjob?jk=19bcecb2f3a86ea3 ## About the Role Do you have experience in Vendor relationship management?, Required: * Advanced degree in epidemiology, biostatistics, health services research, health economics, or related discipline (PhD, MD, PharmD, MPH, MSc). * Minimum of 13 years of relevant pharmaceutical, biotechnology, or HEOR consulting experience. * Minimum of 10 years supervisory years of experience. * Demonstrated expertise in designing and executing observational studies using large real-world datasets across the product lifecycle. * Experience leading center-of-excellence or function-level real-world evidence programs across multiple assets. * Experience building and managing external real-world data vendor partnerships. * Working knowledge of regulatory and HTA evidence requirements. * Experience delivering real-world evidence into value dossiers and HTA submissions. * Strong analytical, quantitative, and methodological expertise. * Excellent communication and interpersonal skills with the ability to influence senior leaders. * Ability to lead, collaborate, and influence cross-functional teams. * Flexible, adaptable, and effective in ambiguous environments. Preferred: * Experience in commercial-stage biotechnology or pharmaceutical organizations. * Experience integrating advanced analytics or AI-enabled platforms into real-world evidence workflows. * Familiarity with ex-U.S. real-world evidence requirements. Physical Demands and Work Environment: Physical Activities: On a continuous basis, sit at desk for a long period of time; intermittently answer telephone and write or use a keyboard to communicate through written means. Some walking and lifting up to 25 lbs. may be required. The noise level in the work environment is typically low to moderate. The physical demands described above are representative of those that must be met by an employee to successfully perform the essential functions and responsibilities of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions and responsibilities. ## Description The Senior Director, Real-World Evidence leads the Real-World Evidence Center of Excellence (RWE COE) within HEOR/RWE, serving as the technical execution engine that designs, conducts, and delivers real-world studies across the Crinetics portfolio. Working from evidence priorities defined by HEOR Therapeutic Area Leads and the Vice President, HEOR/RWE, the role directs a team of RWE Scientists to execute observational studies, claims and EHR analyses, registry analytics, external control arms, comparative effectiveness studies, drug utilization studies, and burden-of-illness research. The role sets technical and methodological standards for the function, builds enterprise real-world data infrastructure in partnership with IT and Commercial, and leads the RWE module of CrinRADAR. Reporting to the Vice President, HEOR/RWE, the Senior Director partners closely with HEOR Therapeutic Area Leads, Medical Affairs, Clinical Development, Biometrics, Patient Advocacy, Market Access, and external academic and data partners. Essential Job Functions and Responsibilities: These may include but are not limited to: * Lead the delivery of the real-world evidence program across the portfolio, translating evidence priorities into rigorous, well-designed real-world studies. * Provide leadership, career management, coaching, and mentoring to a team of RWE Scientists; recruit and develop talent and align team capacity to portfolio demand. * Drive team objectives, prioritization, and resource allocation across competing therapeutic area needs. * Operate across long-range lifecycle planning and near-term execution horizons. * Design and oversee burden-of-illness, natural history, patient journey, drug utilization, external control arm, comparative effectiveness, and HTA-supportive real-world studies. * Contribute to the design and operationalization of Crinetics-sponsored registries and lead registry-related analytics and evidence generation. * Lead analyses using large healthcare databases and primary real-world data collection methods. * Establish methodological standards, protocol templates, statistical analysis frameworks, and quality benchmarks. * Conduct and supervise feasibility assessments, database selection, and study-design innovation. * Partner with IT and Commercial to shape enterprise real-world data sourcing and analytics infrastructure. * Lead the RWE module of CrinRADAR, supporting scalable and automated evidence generation. * Establish data governance, contracting, and vendor management standards for real-world data assets. * Partner with HEOR Therapeutic Area Leads to translate franchise-level evidence questions into executable plans. * Contribute evidence to integrated evidence plans, value dossiers, and HTA submissions. * Collaborate cross-functionally with Clinical Development, Biometrics, Regulatory, and Patient Advocacy. * Build and steward external partnerships with academic investigators, data providers, and analytics vendors. * Lead publication strategy and external scientific communication for the real-world evidence program. * Represent Crinetics at scientific congresses and remain current with evolving real-world evidence methodologies and guidance. * Ensure compliance with corporate policies and applicable healthcare laws and regulations. * Other duties as assigned. ## Related Videos - [Kubernetes and Microservices with Multi-Model Databases](https://www.wearedevelopers.com/videos/382-kubernetes-and-microservices-with-multi-model-databases) - [Biometric Phone Chargers, $40m Domain Names & AI Movies Winning Awards - Peter Kröner](https://www.wearedevelopers.com/videos/1810-biometric-phone-chargers-40m-domain-names-ai-movies-winning-awards-peter-kroner) - [Data Governance in the Era of AI](https://www.wearedevelopers.com/videos/1622-data-governance-in-the-era-of-ai) - [Beyond Gut Feelings: The Rise of Data-Driven HR](https://www.wearedevelopers.com/videos/1326-beyond-gut-feelings-the-rise-of-data-driven-hr) - [Fault Tolerance and Consistency at Scale: Harnessing the Power of Distributed SQL Databases](https://www.wearedevelopers.com/videos/1146-fault-tolerance-and-consistency-at-scale-harnessing-the-power-of-distributed-sql-databases) - [Designing How Work Feels: The Science Behind Sanofi’s Workplace Experience](https://www.wearedevelopers.com/videos/1848-designing-how-work-feels-the-science-behind-sanofi-s-workplace-experience) ## Related Articles - [Fully Remote Software Engineer Jobs](https://www.wearedevelopers.com/magazine/447-fully-remote-software-engineer-jobs) - [Coffee with Developers - Maria Apazoglou - Making AI understandable for all in production](https://www.wearedevelopers.com/magazine/475-coffee-with-developers-maria-apazoglou-making-ai-understandable-for-all-in-production) - [Data Analyst Salary in the UK](https://www.wearedevelopers.com/magazine/278-data-analyst-salary-in-the-uk) - [How to Ensure a Reasonable Salary Before an Interview](https://www.wearedevelopers.com/magazine/322-how-to-ensure-a-reasonable-salary-before-an-interview) - [Best Paying Remote Jobs](https://www.wearedevelopers.com/magazine/255-best-paying-remote-jobs) - [Résumé-Driven Development: How IT trends affect the job market for software developers](https://www.wearedevelopers.com/magazine/59-resume-driven-development-how-it-trends-affect-the-job-market-for-software-developers)