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# Preclinical Safety Profiling Expert, Principal Scientist

- **Company:** Novartis Corporation
- **Location:** Cambridge, MA, United States
- **Experience:** Expert
- **Salary:** $114,100.0 - $222,300.0
- **Contract:** Permanent contract
- **Skills:** Profiling, Data Transmissions, Data Integrity, Data Visualization, Data Generation
- **Published:** June 19, 2026
- **Apply:** https://www.indeed.com/viewjob?jk=c4d0372b2e0927c1

## About the Role

Do you have experience in Toxicology research projects?, * Degree/Advanced Degree in Pharmacology, Toxicology or a Related Field

 * 5+ years of relevant experience in pharmacology / toxicology
 * Understands the basic concepts of hazard identification and risk assessment associated with drug ADME, off-target mitigation and cardiovascular safety.
 * Familiar with early drug discovery processes
 * Experience with data integrity and quality assurance practices.
 * Articulates solutions / recommendations to business users. Presents analytical content concisely and effectively and influences the outcome of predictive safety profiling contributions.
 * Collaborates with internal stakeholders, external partners, and cross-functional teams to solve critical business problems, propose operational efficiencies and innovative approaches.
 * Familiar with visualization tools to increase efficiency and quality of data communication and interpretation.

## Description

* Design and execute the early safety screening & profiling strategies associated with secondary pharmacology and cardiovascular safety, in collaboration with internal and external stakeholders.
 * Primary interface between PCS and our CRO partners.
 * Manage internal relationships with PSP subject matter experts and the outsourcing resource group. Further develop data internalization processes and manage outsourcing budget.
 * Effectively communicate with stakeholders, including experimental design, data quality, timeline requirements and flowchart planning.
 * Understand and execute agreed business strategy defined by local and global Preclinical Safety Profiling requirements, ensuring appropriate coordination of projects.
 * Participate in cross-functional early safety screening & profiling collaborations with Novartis Biomedical Research partners to support the early derisking of compounds, drug targets, and therapeutic modalities
 * Deliver clear and concise presentations for audiences with different expertise
 * In collaboration with cross-functional partners, provide scientific and strategic input to support the early derisking of compounds, drug targets, and therapeutic modalities
 * Ensure quality and compliance of data generation, analyses and resultant reports


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